This is an automatically translated article.
Agicetam 800 is a drug that improves the functional activities of the central nervous system, so it is indicated for use in many neurological diseases. To ensure effective use, patients need to follow the instructions exactly.
1. What does agicetam do?
Agicetam has the main active ingredient piracetam, which is prepared in the form of tablets with different strengths such as agicetam 400 mg equivalent to 400mg piracetam, agicetam 800 mg equivalent to 800mg. So what does agicetam 800mg do, here are some effects of the drug:
Piracetam is considered a euphoric substance. Piracetam acts on a number of neurotransmitters such as acetylcholine, noradrenalin, dopamine... This drug can alter a neurotransmitter and contribute to improving the metabolic environment for nerve cells to function. a better way.
In experimental studies, Piracetam has been shown to protect cells against ischemic metabolic disorders by increasing the brain's resistance to hypoxia. Thanks to that, the brain cells still work well.
Piracetam increases glucose mobilization and utilization independent of pentose-mediated blood oxygen supply and helps maintain energy synthesis in the brain. Agicetam drugs also work to increase the release of the hormone dopamine, which has a good effect on memory formation, thus helping to increase memory. Piracetam also reduces the ability of platelets to agglomerate and in cases of abnormally stiff red blood cells, the drug can restore the deformability of the red blood cells and allow the red blood cells to pass through the capillaries. In addition, the drug also helps to prevent muscle tremors.
2. Indications and contraindications of Agicetam
Thanks to the above effects, the drug is indicated in the following cases:
Diseases caused by brain damage such as ischemic stroke, psychosis, brain injury, after brain surgery. The disease is caused by a disorder in the brain that causes dizziness, headache, and delirium. Sequelae due to CO poisoning. Declining cognitive function and chronic sensory neuropathy in the elderly. Learning difficulties in children, chronic alcoholics. Treatment of myoclonus of cortical origin regardless of etiology and should be used in combination with other anticonvulsant therapies. Prevention and relief of embolic episodes of sickle cell disease in both children and adults. Contraindications: Agicetam is contraindicated in the following cases:
Patients with severe renal failure when creatinine clearance is less than 20ml/min. People with Huntington's disease. The patient had a cerebral hemorrhage. Hypersensitivity to any of the ingredients of the drug. Pregnant women and lactating women.
3. How to use and dose of agicetam
How to use: Take medicine with water, take medicine with or without food. However, the patient should remember not to chew or crush the tablet.
Dosage:
The usual dose is 30 to 160 mg/kg/day, divided equally orally 2 times or 3 to 4 times/day. Long-term treatment of psychosomatic disorders in the elderly with a dose: 1.2 to 2.4 g/day divided into 3 times. The dose may be as high as 4.8 g/day during the first few weeks. Treatment of alcoholism: 12g daily for the first period of alcohol withdrawal. For maintenance treatment, take 2.4g/day, divided into 3 times. Cognitive impairment after brain injury: Initial dose is from 9 to 12g daily, maintenance dose: 2.4g daily and taken for at least 3 weeks. Sickle cell anemia: Used at a dose of 160mg/kg/day, divided equally into 4 times. Treatment of myoclonus: Use 7.2g per day, divided into 2 to 3 times. Depending on response every 3 to 4 days, the dose was increased by 4.8 g/day to a maximum dose of 20 g/day.
4. Note when using Agicetam
Some possible side effects when taking the drug are fatigue, nausea and vomiting, diarrhea, abdominal pain, bloating, irritability, headache, somnolence or insomnia. Because Piracetam can cause drowsiness and tremors, users should avoid driving and operating machinery. Piracetam is eliminated primarily by the kidneys, so caution should be exercised in cases of renal failure. Due to its antiplatelet effect, caution should be exercised when administering to patients with major bleeding, patients at risk of bleeding such as peptic ulcers, patients with coagulopathy, patients with a history of Hemorrhagic stroke... Abrupt discontinuation of Piracetam should be avoided, as it may lead to myoclonic or generalized seizures in some patients with myoclonus. Do not use the drug with alcohol and alcoholic beverages. Do not take the drug with anticoagulants because it increases the risk of bleeding, blood pressure drugs because they can reduce the effect of blood pressure drugs. Cases of overdose are rare, may be seen in patients who abuse the drug and have similar signs of an allergic reaction such as erythema on the skin, itching, digestive disturbances,... When an overdose occurs, it is necessary to take patients to the nearest medical facility for timely treatment. Above are some of the effects and things to know about Agicetam. Note that when using the drug, you should always consult with your doctor or pharmacist to avoid improper use, causing unwanted effects.
Follow Vinmec International General Hospital website to get more health, nutrition and beauty information to protect the health of yourself and your loved ones in your family.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.