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Piracetam is a familiar active ingredient with the ability to nourish the brain. This active ingredient is in Agicetam 1200. So what is Agicetam and what are its effects?
1. What is Agicetam?
What is Agicetam? Agicetam 1200 has the main active ingredient Piracetam 1200mg. Agicetam is a product of Agimexpharm Pharmaceutical Joint Stock Company (Vietnam) and is made in the form of film-coated tablets.
Piracetam in Agicetam 1200 is a cyclic derivative of GABA and is considered an active ingredient that improves nerve cell metabolism. However, the specific effects as well as the mechanism of action of Piracetam have not been clearly defined. Piracetam can affect some neurotransmitters such as Acetylcholine, Noradrenalin, Dopamine ... Therefore, Agicetam 1200 can change the process of neurotransmitters, thereby contributing to improving the metabolic environment for these substances. nerve cells work better. Experimental studies have shown that Piracetam can protect brain cells from ischemic metabolic disorders by stimulating resistance in hypoxia. Besides, Piracetam in Agicetam 1200 also has the effect of increasing mobilization and improving the ability of cells to use glucose regardless of oxygen supply. Thereby, Agicetam 1200 facilitates the pentose pathway and maintains energy synthesis in the brain.
2. Indications of Agicetam 1200
Agicetam 1200 is indicated in the following cases:
Agicetam 1200 is used to treat symptoms of dizziness; When used for elderly patients, Agicetam 1200 helps improve memory impairment, dizziness, poor concentration or lack of alertness, mood swings, behavioral disturbances, poor attention to self, depression, and anxiety. dementia due to multiple cerebral infarction; Agicetam 1200 is used in acute ischemic stroke (also known as cerebral infarction); Agicetam 1200 is also used in the treatment of alcoholism; Treatment of sickle cell anemia; Support in the treatment of myoclonic tremor of cortical origin.
3. How to use, dosage of Agicetam 1200
How to use: The patient should take Agicetam 1200 with a glass of water, with or without food.
Dosage of Agicetam 1200 specifically prescribed by the doctor:
The usual dose for adults is 30-160 mg/kg/day, divided into several oral doses (maybe 2 times or 3-4 times); Maintenance treatment of psychosomatic syndromes in the elderly: Agicetam is recommended at a dose of 1.2-2.4g/day, depending on the case. The maximum dose can be up to 4.8g/day in the initial period of treatment; Treatment of Alcoholism: The recommended dose of Piracetam is 12g/day during the initiation of alcohol withdrawal. After that can be maintained at a dose of 2.4g/day (equivalent to 2 Agicetam 1200 tablets); Dose in the treatment of cognitive impairment after brain injury (with or without dizziness): The initial dose is 9-12 g/day, then maintained at 2.4g. The use of Agicetam 1200 in this case requires at least 3 weeks; Sickle cell anemia: The recommended dose of Agicetam is 160 mg/kg/day, divided into 4 oral doses; Treatment of myoclonic tremor: The recommended dose is 7.2 g/day, divided into 2-3 oral doses. Depending on the patient's response, it can be increased by 4.8g/day every 3-4 days to a maximum dose of 20g/day. Once the optimal dose of Piracetam has been reached, the physician should seek to reduce the dose of concomitant medications. The dose of Agicetam 1200 for patients with renal failure needs to be adjusted appropriately according to the creatinine clearance:
Creatinine clearance coefficient 50-79 ml/min: Dosage is equal to 2⁄3 normal doses, divided orally 2-3 times/ day; Creatinine clearance 30-49 ml/min: The dose is equal to 1⁄3 of the usual dose, divided into 2 oral doses per day; Creatinine clearance 20-29 ml/min: It is recommended to take 1⁄6 normal doses, 1 time per day.
4. Contraindications of Agicetam 1200
Agicetam 1200 is contraindicated in the following cases:
Patients with hypersensitivity to Piracetam or any component of Agicetam 1200; People with severe renal dysfunction (creatinine clearance < 20 ml/min); The patient has Huntington's chorea; Patients with liver failure should not take Agicetam 1200; Brain hemorrhage; Pregnancy and lactation period.
5. Be careful when using Agicetam 1200
Caution when using Agicetam 1200 in the following cases:
Because Piracetam is eliminated by the kidneys, the increased half-life of Agicetam 1200 is directly related to renal function and creatinine clearance. Therefore, extreme caution should be exercised when using Agicetam 1200 for renal failure. Also, renal function should be monitored in these patients and in elderly patients (dose adjustment is required based on creatinine clearance). Abrupt discontinuation of Agicetam 1200 in patients with myoclonus should be avoided as it may increase the risk of convulsions. Agicetam 1200 should be used with caution in patients with peptic ulcers, a history of hemorrhagic stroke, and concomitant use of other bleeding agents due to the increased risk of bleeding. Agicetam 1200 has the potential to cause some potential bleeding disorders; Use of Agicetam 1200 in pregnancy and lactation: Agicetam 1200 is not recommended during pregnancy or lactation. Women with a high chance of becoming pregnant should use contraception before using the drug. Effects of Agicetam 1200 on the ability to drive and use machines: The drug has almost no influence on the ability to drive and use machines. However, there have been few reports of the risk of dizziness, so the doctor may, on a case-by-case basis, recommend or not recommend that a patient take Agicetam 1200 when driving or operating machinery. Incompatibilities of the drug Agicetam 1200: Currently, there are no studies on the incompatibility of the drug, so to ensure safety, do not mix Agicetam 1200 with other drugs.
6. Undesirable effects of the drug Agicetam
Common side effects of Agicetam:
Body fatigue; Nausea, diarrhea, abdominal pain; Abdominal distention ; Restlessness, excitability, headache, insomnia or drowsiness. Some uncommon side effects:l of Agicetam 1200:
Dizziness, weight gain, weakness; Tremor, nervousness, hyperactivity, depression; Blood clotting disorders causing heavy bleeding; Dermatitis, itching and urticaria. Agicetam 1200 has the active ingredient Piracetam 1200mg. The drug is indicated for the treatment of a number of neurological diseases such as dizziness, memory impairment, .... To ensure effective use and avoid side effects, patients need to carefully read the instructions and at the same time. Follow the instructions given by your doctor or pharmacist.
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