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Similar to Penicillin, the drug Standacillin has the active ingredient Ampicillin which acts on the multiplication of bacteria, inhibits the synthesis of the peptidoglycan layer of the bacterial cell wall. Therefore, Standacillin is often indicated for the treatment of infections caused by susceptible bacteria.
1. What is Standacillin?
Standacillin is a beta-lactam antibiotic, belonging to the Aminopenicillin subgroup. The drug has the main ingredient Ampicillin and is made in the form of hard capsules.
2. What does standacillin do? Standacillin is usually indicated for the treatment of infections caused by susceptible bacteria:
Upper respiratory tract infections (sinusitis, epiglottitis...); Gonorrhea , gonorrhea urethritis , gonococcal infection ; Meningitis ; Listeria infection ; Leptospira infection ; Sepsis in infants and young children (usually in combination with Aminoglycoside antibiotics); In addition, the drug is also used after treatment with ampicillin injection, as a prophylactic antibiotic.
Standacillin hay được chỉ định để điều trị nhiễm trùng do các vi khuẩn nhạy cảm gây ra
3. Instructions for using the drug Standacillin
Standacillin is taken orally 1-2 hours before meals. Dosage depends on the type of disease, severity, age and kidney function of the patient. Dosage should be reduced in patients with severe renal impairment.
Reference dosage for adults:
Usual dose: 0.25-1g Ampicillin/time, every 6 hours/time. For severe disease, consider taking 6-12g/day; Gonorrhea: Use a dose of 2-3,5g in combination with 1g of Probenecid, taking a single dose. For women, Standacillin can be repeated once if needed. Reference dosage for children:
Respiratory or skin infections: For children weighing ≤ 40kg: 25 - 50 mg/kg/day in equally divided doses, every 6 hours. Urinary tract infections: Take 50-100 mg/kg/day, every 6 hours, should be divided into 3-4 times to drink. The actual duration of treatment depends on the type and severity of the infection. For most infections (except gonorrhea), treatment should be continued for at least 48-72 hours after the patient has cleared of symptoms.
Reference dosage for patients with renal failure:
For patients with creatinine clearance 30ml/min or higher: Similar to the usual dose in adults. Creatinine clearance 10 ml/min or less: Take the usual dose every 8 hours. Patients on hemodialysis must receive an additional dose of ampicillin after each dialysis period. *Note: The above dosage is for reference only. The specific dose depends on the condition and the progression of the disease. To get the right dose, the patient should consult a doctor or medical professional.
4. Side effects of the drug Standacillin
During treatment with Standacillin 500mg, patients may encounter unwanted side effects such as:
Diarrhea; Urticaria, erythema multiforme, pruritus; Fever; Blood disorders (anemia, eosinophilia, thrombocytopenia, leukopenia and leukopenia...); Glossitis, stomatitis; Nausea and vomiting; Colitis and pseudomembranous colitis ; 5. Notes when using the drug Standacillin Contraindicated using the drug Standacillin in the following cases:
People at risk of hypersensitivity to any component of the drug (especially Penicillin); Infectious mononucleosis ; Lymphocytic leukemia ; Use caution when using Standacillin in the following cases:
People are sensitive to antibiotics of the Cephalosporin group; Patients with renal failure; If used for a long time (more than 2-3 weeks), it is necessary to periodically check liver and kidney function & hematopoietic system.
Thuốc Standacillin được dùng qua đường uống 1-2 giờ trước bữa ăn
6. Standacillin drug interactions
Standacillin can interact with some drugs such as:
Antacid neutralizer; High blood pressure medicine Atenolol , Gout medicines such as Allopurinol and Probenecid; The immunosuppressive drug Methotrexate ; Bacteriostatic antibiotics such as: Chloramphenicol, Erythromycin, Tetracycline; In addition, Ampicillin may falsify the results of urine glucose tests using copper sulphate (eg, Clinitest reagent, Benedict). Food also reduces the rate and extent of absorption of Standacillin.
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