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Drug Mebilax 7.5mg main ingredient meloxicam is used to treat persistent pain in osteoarthritis pain. Patients taking the drug should read the instructions carefully or consult a doctor or pharmacist.
1. What are the effects of Mebilax 7.5?
Mebilax medicine 7.5mg main ingredient meloxicam. Mebilax medicine 7.5mg is used in the treatment of diseases with chronic pain symptoms such as:
Rheumatoid arthritis Ankylosing spondylitis Osteoarthritis pain (joint damage, osteoarthritis)
2. Pharmacodynamics of Mebilax 7.5mg
Mebilax 7.5mg contains the main ingredient meloxicam. This active ingredient is a non-steroidal anti-inflammatory drug, belonging to the group of oxicam derivatives with analgesic, antipyretic and anti-inflammatory effects. Their mechanism of action is to inhibit the biosynthesis of prostaglandin mediators that cause inflammation, pain, and fever.
Mebilax 7.5mg có chứa thành phần chính là meloxicam
3. Pharmacokinetics of Mebilax 7.5mg
After entering the body, Meloxicam is well absorbed with an average bioavailability of up to 89%. This active substance is strongly bound to albumin and other components of plasma proteins. The drug is extensively metabolised in the liver and is mainly excreted in the urine and faeces. The mean half-life is about 20 hours.
4. How to use Mebilax 7.5
The drug is used orally. Dosage will vary depending on age and medical condition.
For patients with rheumatoid arthritis or ankylosing spondylitis, the usual dose of 15mg includes 2 tablets per day. Depending on the patient's response to treatment, the dose can be reduced to 7.5 mg with 1 tablet/day. In case patients present with acute pain of osteoarthritis, the dose of 7.5mg with 1 tablet per day will be used. When necessary, the dose can be increased to 15mg with 2 tablets / day. Subjects at risk of adverse events or the elderly are usually initiated with a dose of 7.5 mg. Patients on hemodialysis take no more than 7.5mg/day. In case of severe renal impairment, this drug should not be used. Note that the above dosage is for reference only and is not applicable to all cases. The doctor can base on the actual condition of the patient and the progression of the disease to determine the appropriate dose.
Thuốc Mebilax 7.5 được sử dụng với đường uống
5. Some notes when using Mebilax 7.5
5.1. Contraindications Mebilax 7.5 has some of the following contraindications:
Patients with a history of allergy to any component of the drug Patients allergic to aspirin and NSAID pain relievers Patients with symptoms urticaria, bronchial asthma, angioedema, nasal polyps, Quincke's edema after use of aspirin and other NSAIDs, gastric ulcer, progressive gastric and duodenal bleeding, cerebral bleeding. Patients with severe hepatic impairment or severe renal impairment are not on dialysis. Pregnant and lactating women. 5.2. Precautions for use Mebilax 7.5 should be used with caution in the following cases:
Patients with upper gastrointestinal diseases such as peptic ulcer or gastrointestinal bleeding and patients being treated with anticoagulants. For patients with end-stage renal failure, meloxicam should not be used in excess of 7.5 mg/day. In case of mild or moderate renal impairment, no dose reduction is required. When a significant increase in transaminase levels is detected in a patient, the drug should be discontinued and a follow-up test or other liver function parameters performed. People who operate machinery or drive should be cautious when using this medicine because of the potential for side effects such as dizziness and drowsiness. Meloxicam is recommended by experts not to be used by pregnant women, especially in the last 3 months of pregnancy. 5.3. Interactions between Meloxicam and other drugs When combining Mebilax 7.5mg and other non-steroidal anti-inflammatory drugs (NSAIDs) there is an increased risk of gastrointestinal ulceration or bleeding. On the other hand, when used together with anticoagulants, there is the potential to dissolve blood clots and increase the risk of bleeding.
Meloxicam when taken with methotrexate increases the level of lithium in the blood. Concomitant use of diuretics may increase the risk of acute renal failure in dehydrated patients. In addition, Meloxicam may reduce the effect of antihypertensive drugs.
Drug Mebilax 7.5mg main ingredient meloxicam is used to treat persistent pain in osteoarthritis pain. To ensure the effectiveness of treatment and avoid side effects, patients need to take medicine according to prescription or consult a doctor, professional pharmacist.
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