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Zemuron belongs to the group of neuromuscular blocking drugs, non-polar, is a drug prescribed to help relax muscles before general anesthesia, routine intubation... So what is the use of Zemuron?
1. What does Zemuron do?
Zemuron injection (rocuronium bromide) is a non-polar neuromuscular blocker with a rapid to intermediate onset depending on the dose and duration of mediation. Rocuronium bromide is chemically denoted 1- [17β- (acetyloxy) -3α-hydroxy-2β- (4-morpholinyl) -5α-androstan-16β-yl] -1- (2-propenyl) pyrrolidinium bromide. Zemuron belongs to the group of non-polar neuromuscular blocking agents. This is a prescription medication that relaxes muscles before general anesthesia. Zemuron may be used alone or in combination with other drugs indicated in general anesthesia to facilitate routine intubation and to relax skeletal muscles during surgery or mechanical ventilation.
2. Usage and dosage of the drug Zemuron
Zemuron is prepared as a sterile, hypoallergenic, transparent, colorless intravenous solution for intravenous injection. Each ml contains 10mg rocuronium bromide and 2mg sodium acetate. The drug solution is adjusted to isotonic with sodium chloride to a pH of 4 with acetic acid and sodium hydroxide. Zemuron should only be used by experienced clinicians or by persons trained in anesthesiology.
The dose of the drug depends on the patient's condition as well as the weight and age. The usual recommended dose is 0.6 mg/kg. However, for each specific case, the dosage will be different such as:
For pediatric patients, the recommended initial intubation dose is 0.6mg/kg. However, a lower dose of 0.45 mg/kg may be used depending on the anesthetic technique and the age of the patient. For geriatric patients, the mean clinical time was slightly prolonged about 46, 62, 94 minutes when using opipod, nitrous, and pxxy under the respective doses and 0.6mg/kg; 0.9mg/kg; 1.2mg/kg. For obese patients, the initial dose of 0.6 mg/kg should be based on the patient's body weight.
3. Undesirable effects when using the drug Zemuron
Some unwanted effects that may occur when using Zemuron include:
Lightheadedness Headache Blurred vision Anxiety or confusion Shortness of breath Severe dizziness Muscle weakness Loss of movement in any part of the body body Before prescribing a drug, doctors always weigh the benefits and effectiveness of Zemuron more than the risk of side effects. However, in some cases when using Zemuron, unwanted effects may still occur. Therefore, when unusual symptoms appear after taking the drug, and especially when a severe allergic reaction occurs, there are some signs such as severe dizziness, difficulty breathing, face and neck area. throat and tongue swelling, rash or itching,... When suffering from one of the above symptoms, the patient or family member should immediately notify the medical staff for timely treatment.
4. Some notes when using Zemuron
Some notes when using Zemuron include:
Inform your doctor about any history of hypersensitivity, allergy to Zemuron or any other allergies. Zemuron may contain ingredients that don't work and could cause an allergic reaction or other serious problems. In addition, report any medications you are taking including: prescription drugs, over-the-counter drugs, herbs, dietary supplements or foods or preservatives or dyes. Zemuron should be used with caution in patients under 3 years of age.
5. Drug interactions Zemuron
Drug interactions can reduce the effect of Zemuron, or increase the effect of unwanted effects. Tell your doctor about all other medicines you are taking including: vitamins, prescription and over-the-counter medicines or other herbal products. Users should not stop, start or change the dosage of any medication without their doctor's approval.
Some drugs that may interact with Zemuron include:
Amphotericin Amoxicillin Azathioprine Cefazolin Dexamethasone Diazepam Erythromycin Famotidine Furosemide Insulin Intralipid Ketorolac Lorazepam Methohexital Methylprednisolone Thiopental Trimethoprim Vancomycin Hydrocortisone sodium succina
6. How to store Zemuron
Store Zemuron at room temperature, away from light and away from moisture. Do not store Zemuron in a humid place or in the freezer. Different medicines will have different storage methods, so read Zemuron's storage instructions carefully on the packaging, or ask your pharmacist.
Keep Zemuron out of reach of children and household pets. In addition, when the medicine has expired or is damaged and cannot be used anymore, it should be handled according to the correct procedure.
In summary, Zemuron belongs to the group of neuromuscular blocking drugs, non-polar, is a drug prescribed to help relax muscles before general anesthesia, routine intubation... However, Zemuron has It can cause some unwanted effects and drug interactions, so it's important to tell your doctor about the doses of medicines you have been taking to reduce the risk of unwanted effects, and make increase the effectiveness of the treatment.
