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Zealargy drug works to reduce symptoms caused by allergies such as rhinitis, urticaria ... without causing side effects. The drug does not cause drowsiness, so it can be used by people who need to operate machinery.1. Uses of Zealargy
Zealargy drug has the main ingredient is Rupatadine 10mg, is made in the form of tablets.
Rupatadine is a second generation antihistamine with anti-Histamine H1 and anti-PAF effects. This combined effect makes the drug anti-inflammatory, non-sedating, non-cardiogenic, and can be used for long-term treatment of people with year-round allergies.
In the formula of the drug, there is an anti-H1 group and a group of anti-platelet activating factors (PAF), which helps bring about dual anti-histamine and anti-PAF effects.
When an allergic person's body comes into contact with an allergen, it will cause an allergic reaction. In particular, Histamine is the main chemical mediator produced, contributing to the symptoms of allergic conditions.
While PAF is a potent phospholipid, produced by inflammatory cells, PAF is a mediator that increases vascular permeability and attracts eosinophil chemotaxis, increasing inflammation. Recent studies have shown the role of PAF in allergic rhinitis, which induces a wide range of responses in these patients to reduce disease symptoms.
After a single oral dose of 10 mg Rupatadine reaches maximum plasma concentrations 45-60 minutes, faster than some other antihistamines.
A number of studies were conducted to evaluate the use of Zealargy, making some comments about the drug:
A study of the use of the drug after 4 weeks of treatment with Rupatadie, the proportion of patients with rhinitis. severe allergies has decreased from 97.5% to only 39.4%. The effects noted in these reports include improvement in allergy symptoms and in particular in the nose, reduced runny nose, less sneezing, completely reduced symptoms of nasal congestion and itchy nose, and reduced itchy and watery eyes . The drug is considered safe because it does not cause drowsiness, does not affect the ability to drive machines or vehicles, does not cause toxicity on the heart and is safe when used for 6 months. Drugs used to treat urticaria: Helps relieve symptoms of chronic urticaria such as itching and the number of skin rashes at weeks 4 and 6.
2. Indications and contraindications to the use of Zealargy
Zealargy medicine 10mg is indicated in the following cases:
Treatment of symptoms of perennial allergic rhinitis and seasonal allergic rhinitis in adults and children over 12 years old. Treatment of symptoms of allergic conjunctivitis in people over 12 years of age. Urticaria in adults and children over 12 years of age. Contraindications to use Zealargy:
Do not use if the patient has a history of hypersensitivity reactions to any ingredient of the drug. The drug should not be used by pregnant women in the first 3 months of pregnancy Do not use this dosage form in children under 12 years of age. For children 2-12 years of age, use Rupatadine as an oral solution. 3. How to use and dose Zealargy How to use: The drug is taken orally and can be taken before or after eating.
Dosage: For adults and children over 12 years old, take 10 mg (1 tablet), once daily. The duration of drug use depends on each case of different diseases, it can be used for symptomatic periods or for a long time with year-round allergies.
4. Notes when taking Zealargy To use the drug safely and effectively you need to keep a few things in mind:
When taking the drug can cause some side effects, although not common, including: Fatigue: Fatigue fatigue, headache, drowsiness, dry mouth, dizziness. If you see any side effects that affect your body, you should notify your doctor for timely treatment. In case of severe symptoms, seek medical attention immediately. The drug should be taken according to the doctor's prescription, some recommendations for Rupatadine drug suggest that regular treatment should be carried out for people with unknown allergens, should take the drug in the morning, when eating and the drug has an effect. use all day. Do not wait for symptoms to appear before taking the medicine. Possible Drug Interactions When Co-administered: Zealargy should not be combined with Ketoconazole or Erythromycin because these drugs increase the systemic absorption of Rupatadine by up to 10-fold. Zealargy should not be taken with grapefruit juice because this juice increases systemic absorption up to 3.5 times. Store the medicine in a cool, dry place. Keep out of reach of children. Hopefully through the article you know the information about the uses, dosage and precautions when using Zealargy 10mg. If you have any questions, consult your doctor or pharmacist.
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