This is an automatically translated article.
What is Virless Cream? Virless Cream 5% belongs to the group of antiparasitic, antifungal and antibacterial drugs. The drug is in the form of a cream that is applied to the skin. How to use and how to use Virless Cream 5% specifically, please refer to the article below.
1. What is the effect of Virless Cream?
The drug contains the active ingredient Acyclovir with a strength of 50mg and other excipients just enough. Virless Cream 5% is commonly used in the treatment of skin infections caused by the Herpes Simplex virus, including initial and recurrent genital herpes and herpes simplex.
Do not use the drug for patients who are allergic or sensitive to the active ingredient Acyclovir or other ingredients of the drug.
2. Pharmacokinetics and pharmacokinetics of Virless Cream 5%
Acyclovir is a synthetic purine nucleoside analogue. This active substance has potent inhibitory activity in vitro and in vivo against the human herpes virus.
Acyclovir will be partially absorbed from the intestine. Following doses of 200 mg administered every 4 hours, mean steady-state maximal plasma concentrations (Cmax) were 3.1 micromoles (i.e. 0.7 mcg/mL) and min (Cmin) were 1.8 mcg/mL. micromoles (ie 0.4mcg/ml). After doses of 400 mg and 800 mg every 4 hours, peak concentrations were 5.3 micromoles (1.2 mg/ml) and 8 micromols (1.8 mg/ml), respectively, with troughs respectively 2.7 micromol (ie 0.6mg/ml) and 4 micromol (ie 0.9 mg/ml). Topical acyclovir is rapidly absorbed through the corneal epithelium and surface tissues of the eye, resulting in concentrations that are toxic to the virus in the aqueous humor. No acyclovir was detected in the blood after topical application, but quantitative traces of the drug were found in the urine but no therapeutic effect.
When acyclovir was used for the whole body, international standard tests did not show fetal toxicity or teratogenicity in rabbits, mice, and rats. Experimental studies in two generations of rats found no effect of acyclovir when administered orally on fertility nor in humans. Tablets containing Acyclovir have shown no definite effect on sperm count, morphology and motility in humans.
3. Dosage and how to use Virless Cream 5%
Recommended dose for adults and children: Apply to the affected area 5 to 6 times daily. Each time is 4 hours apart and the treatment time is within 5 days.
In case after 5 days, the wound has not healed, continue to re-treat for the next 5 days. Treatment should be started as soon as possible, as soon as a viral infection is detected. In case of re-infection, treatment is also required as soon as the first lesion appears.
4. Note when using Virless Cream 5%
The side effects of Virless cream 5% may appear such as: rash, burning sensation, itching. The drug is for external use only, avoiding the eye area; Do not drink or put vaginally; Do not arbitrarily overdose Virless cream 5% Use only with the frequency as recommended; It is necessary to carefully consider and have a doctor's prescription when using Virless cream 5% for pregnant and lactating women.
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