This is an automatically translated article.
Vexprazole 40 is a gastrointestinal drug, the main active ingredient is pantoprazole, which reduces acid secretion in the stomach by inhibiting the proton pump. It is commonly used to treat gastroesophageal reflux disease and peptic ulcers.
1. What are the effects of Vexprazole 40?
Vexprazole 40 (Pantoprazole) is an gastrointestinal drug commonly used in cases of gastroesophageal reflux and gastrointestinal ulcers. The dosage form of the drug is enteric coated tablets, content of 40mg Pantoprazole. In this dosage form, the amount of active substance inside is protected from contact with gastric acid in the stomach, but will dissolve in the small intestine and release the drug for absorption. Pantoprazole active ingredient in the drug inhibits the proton pump (enzyme H + / K + - ATPase) present on the surface of gastric parietal cells, preventing acid secretion into the stomach lumen. Therefore, the drug has an inhibitory effect on acid secretion even when the stomach is stimulated by any agent. Thanks to that mechanism, the drug vexprazole 40mg is used to treat diseases of the gastrointestinal tract: gastroesophageal reflux disease (GERD), peptic ulcers, Zollinger-Ellison syndrome causing pathological hypersecretion, and prevention of gastritis. due to the use of non-steroidal anti-inflammatory drugs (NSAIDs).
On the other hand, Vexprazole 40 is not indicated for the following cases:
People with a history of allergy to pantoprazole or benzimidazole derivatives such as rabeprazole, omeprazole, lansoprazole, esomeprazole. Women who are breastfeeding.
2. How to use and dosage of Vexprazole 40mg
2.1. How to use Take the drug with water, whole tablet, do not chew or break the tablet. You should take the medicine 30 to 60 minutes before meals. 2.2. Dosage: Gastroesophageal reflux disease (GERD): 20-40 mg orally once a day, treatment for 4 weeks, can last up to 8 weeks, maintenance dose: 20-40 mg daily . Dose for treatment of relapse: 20mg/day. Gastrointestinal ulcers: for duodenal ulcers, the dose is 40mg x 1 time/day (from 2-4 weeks). Benign stomach ulcers 40mg once a day (from 4 to 8 weeks). Eradicating Helicobacter pylori: Using a trio of drugs: Vexprazole 40 mg x 2 times/day in combination with clarithromycin 50mg x 2 times/day and amoxicillin 1g x 2 times/day or metronidazol 400 mg x 2 times/day. treatment for 3 weeks. Prevention of ulcers caused by non-steroidal anti-inflammatory drugs: usually 20mg/day. Zollinger - Ellison syndrome: 80mg/day divided into 2 doses. Doses up to 240 mg/day may be used. Patients with hepatic impairment: maximum dose: 20 or 40 mg/day orally every other day. Patients with renal impairment: Maximum dose: 40 mg/day.
3. Side effects of Vexprazole 40
Vexprazole 40mg medicine can cause unwanted effects such as: gastrointestinal infections, fatigue, headache, urticaria, muscle pain, joint pain. In rare cases, rashes, acne, exfoliative dermatitis, alopecia, stomatitis, digestive disorders, insomnia, somnolence have been reported. Laboratory tests may show elevated liver enzymes, eosinophilia, agranulocytosis, leukopenia, and thrombocytopenia.
You need to immediately notify a qualified doctor/pharmacist when you see unusual signs during the course of taking the drug.
4. Drug interactions and notes during the use of Vexprazole 40mg
When using Vexprazole 40 in combination with drugs such as ampicillin ester, ketoconazole, iron salts, ..., when the gastric pH increases, it may increase or decrease the interaction ability and absorption level of the drug. . Concomitant use of Vexprazole 40 and warfarin increases the risk of abnormal bleeding and death due to an increase in prothrombin time. Sucralfate can slow absorption and reduce bioavailability of Vexprazole 40, so you should take Vexprazole 40 at least 30 minutes before taking sucralfate. Long-term use of the drug, especially at high doses, may increase the risk of fractures, severe hypomagnesemia. thus delaying the diagnosis. Pregnant women and children under 18 years of age need to consult a doctor before using the drug Currently you can easily buy Vexprozole 40 at many pharmacies and hospitals. However, you should not arbitrarily use the drug, you should discuss with your doctor for appropriate indications and follow the instructions properly.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
