This is an automatically translated article.
Ventavis medicine contains the main ingredient Lloprost 10mcg, which is used to treat high blood pressure. The following is useful information about Ventavis to help patients use the drug most effectively and safely.
1. What is Ventavis?
Ventavis belongs to the group of drugs acting on blood, manufactured in the form of a spray solution and packaged in vials.
Ventavis medicine has the main ingredient Lloprost 10mcg and some other excipients, just enough for 1 bottle.
2. What are the uses of Ventavis?
Ventavis drug is used for patients in the following cases:
Primary and secondary pulmonary hypertension with moderate or severe disease. Pulmonary hypertension secondary to mild or severe pulmonary embolism due to chronic inoperable pulmonary embolism.
3. Dosage - How to take Ventavis
3.1. How to use Ventavis medicine Ventavis medicine is prepared in the form of a solution, used by injection directly into the mouth.
3.2. Dosage The dose of Ventavis drug depends on each subject and the course of the patient's pathology. Here is the reference dose of Ventavis as follows:
For adults: When taking Ventavis, the starting dose is 2.5mcg Lloprost/time. Then can gradually increase to 5mcg Lloprost / time. In 1 day divided into 6-9 sprays. For patients with hepatic impairment : Special caution should be exercised in patients with hepatic impairment while taking Ventavis . Because when you have liver failure, the excretion of iloprost will be reduced. Above all, people with liver failure should not arbitrarily accumulate drugs to take for a long time without a doctor's instructions and instructions. It is necessary to treat the disease with a starting dose of 2.5 μg with an interval of 3: 4 hours equivalent to a maximum dose of 6 times / day. The dose can be reduced later based on the patient's tolerability. In case of dose adjustment requiring an increase in dose to 5.0 μg, the initial dose interval should be maintained at 3-4 hours and then the dose should be reduced according to the patient's tolerability results. For patients with renal failure: Ventavis is used for patients with clearance > 30ml/min. Caution should be exercised in administering Ventavis to patients with a clearance <30 mL/min.
4. Contraindications of the drug Ventavis
Ventavis is not for use in people:
Hypersensitivity or history of allergy to Lloprost and some of the other excipients contained in the drug. Pregnant women and lactating women. Children < 18 years old. Progressive peptic ulcer, lesions, and intracranial bleeding. Have severe coronary artery disease and unstable angina . Patients with myocardial infarction within the last 6 months. Have decompensated heart failure without a doctor's supervision. Patients with valvular heart disease with clinical manifestations related to cardiac function but not related to pulmonary hypertension. Severe arrhythmia, suspected pulmonary congestion, cerebrovascular disease such as: transient ischemic attack, stroke, etc. within the last 3 months. Pulmonary hypertension due to venous occlusion.
5. Be careful when taking Ventavis
Patients should note that Ventavis is not used to treat patients with unstable pulmonary arterial pressure, advanced right heart failure, and patients with systolic blood pressure < 85 mmHg. The drug must be used with caution in patients with low systemic blood pressure, acute pneumonia, chronic pulmonary embolism and severe asthma. When using, it is necessary to avoid letting the Ventavis spray solution come into direct contact with the skin and eyes, pay attention not to drink the Ventavis solution. During Ventavis inhalation, the patient should use a fractional dose inhaler and avoid the use of a mask. In case the patient is at risk of fainting: Care should be taken to monitor vital signs when starting Ventavis. For patients with low systemic blood pressure: When using Ventavis, caution should be taken to cause a decrease in blood pressure. Note, do not use Ventavis for patients with systolic blood pressure >85mmHg. For patients with bronchospasm: When using Ventavis inhaler, there is a high risk of bronchospasm, the most dangerous in patients with increased activity in the bronchi. Patients with acute pneumonia, chronic pulmonary embolism and patients with severe asthma should be closely monitored while taking Ventavis. For patients with pulmonary venous hypertension: Ventavis should not be initially administered to patients with pulmonary hypertension due to pulmonary venous thrombosis if these patients are operable. In the event that pulmonary edema is observed, the possibility of pulmonary arterial hypertension associated with pulmonary venous obstruction should be considered. In this case, treatment with Ventavis must be discontinued. For patients with liver and kidney failure: The standard starting dose of the drug for patients with liver and kidney failure with intermittent doses of 3-4 hours has been recommended. As the elimination of Lloprost will be reduced in patients with liver dysfunction and in patients with renal failure requiring hemodialysis. For drivers and machine operators: When using Ventavis medicine to treat diseases, it is necessary to pay attention before any effect of the drug on the body is confirmed. Usually, patients with symptoms of hypotension such as dizziness, the ability to drive and use machines will be affected. Pregnant women: Currently, there is not enough information about the treatment of disease with Ventavis for pregnant women. Because of the current composition Iloprost and its metabolites have not been determined to be excreted in breast milk and have an effect on the infant. Therefore, when being prescribed to treat diseases with Ventavis medicine, breastfeeding should be stopped. For women with pulmonary hypertension, it is important to avoid pregnancy because it can make the condition worse, which can be life-threatening. Women of childbearing age must use effective methods of contraception and be sure to not become pregnant while taking Ventavis.
6. Drug interactions of the drug Ventavis
Do not use Ventavis in combination with beta-blockers, Ca antagonists, vasodilators, ACE inhibitors, anticoagulants, antiplatelet agents.
7. What side effects does Ventavis cause?
When using Ventavis for treatment, patients will experience some unwanted side effects such as:
Common:
Vasodilation; Dizziness, hypotension, fainting; Diarrhea, nausea; Headache, chest pain, jaw pain, back pain; Shortness of breath, cough, sore throat - larynx, sore throat; Jaw stiffness, mouth and tongue irritation including pain; Rash. Serious:
Hypotension; Nosebleeds, coughing up blood; Bronchospasm/wheezing; Taste disorder. If you experience these symptoms, you need to stop using Ventavis and notify your doctor for appropriate treatment.
Above is all information about Ventavis medicine, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Note, Ventavis is a drug prescribed by a specialist, patients absolutely cannot use it on their own.
