Uses of Vasotrate 30

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1. What is Vasotrate 30 mg? The effect of the drug Vasotrate 30mg

Drug Vasotrate 30 OD is a drug used in the prevention of angina pectoris caused by coronary artery disease, treatment of severe heart failure and hypertension for pulmonary artery disease, with the active ingredient is Isosorbide Mononitrate. One tablet of Vasotrate 30 OD contains: Active ingredient: Isosorbide Mononitrate: 30mg. In addition, the drug also includes other excipients, just enough for 1 tablet/blister/box.
Vasotrate 30 OD also has dosage forms as Vasotrate 10 mg / 100 mg, 25 mg / 100 mg, or 12.5 mg / 50 mg capsules.
1.1. Pharmacodynamics of the drug Vasotrate 30 Pharmacodynamics of the active ingredient Isosorbide Mononitrate:
Relaxes all smooth muscles except skeletal and cardiac muscles, thereby reducing myocardial oxygen consumption and cardiac output. Peripheral vasodilation leads to decreased blood flow in the heart. Coronary vasodilation increases blood flow through the coronary arteries. Reducing peripheral resistance and blood flow in the heart during systole should lower blood pressure. Dilates vascular smooth muscle, directly acting to dilate coronary arteries, reducing the workload on the heart and improving the balance between the amount of oxygen supplied by the heart and the amount of oxygen needed by the heart muscle. Relaxes smooth muscle in parts such as bronchi, biliary tract, gastrointestinal tract, urinary tract and genital tract. Changes the distribution of blood in the heart, increasing circulation to the ischemic area (this effect is beneficial to the subendocardial region). Inhibits thrombus formation, especially in damaged endothelium. 1.2. The effect of the drug Vasotrate 30 Isosorbid dinitrate has a relaxing effect on all smooth muscles, does not affect cardiac and skeletal muscles, has a very pronounced effect on both large arteries and veins, so it reduces the amount of venous blood returning and dilation of large arteries. Therefore, the drug is effective in reducing myocardial oxygen use and reducing cardiac function. Direct and transient systemic vasodilation. Therefore, Vasotrate 30 reduces cardiac output, dilates coronary vessels, temporarily increases coronary flow, reduces peripheral resistance and systolic flow. Therefore, the drug Vasotrate 30 has the effect of lowering blood pressure. Vasotrate 30 drugs change the blood distribution to the heart, increase the auxiliary circulation to the ischemic heart area, and benefit the subendocardial area. Vasotrate 30 also has an antiplatelet effect, preventing fibrinogen from attaching to platelets to form thrombus, especially in the damaged endothelium. Vasotrate 30 relaxes tracheobronchial smooth muscle, gastrointestinal smooth muscle, biliary tract smooth muscle, urinary and genital smooth muscle, antagonizing the spasmodic effect caused by Acetylcholine and Histamine active ingredients.

2. What diseases does Vasotrate 30 mg treat?

Vasotrate 30 mg is indicated in the following cases:
Vasotrate 30 is a leading drug that works to treat angina pectoris in the extrinsic, fast pain relief and has a very good effect on pain. Prinzmetal's angina. Prophylactic treatment with angina pectoris. Treatment of myocardial infarction, caused by drugs narrowing the ischemic and extracorporeal area. Treatment for people with high blood pressure, myocardial infarction. Treatment of congestive heart failure, especially left heart failure with increased pulmonary capillary pressure and increased peripheral resistance.

3. Usage and dosage of Vasotrate 30

3.1. How to take Vasotrate 30 You should use Vasotrate 30 in the morning after waking up. The drug is in the form of a film-coated tablet with grooves, so it can be broken in half, absolutely do not chew or crush the tablet.
3.2. Dosage of Vasotrate 30 Dosage: The recommended starting dose is 30-60mg once daily. Thereafter, the single therapeutic dose may be increased to 120 mg per day.
3.3. In case of overdose/forgotten dose In case of overdose: Manifestations of an overdose of Vasotrate 30 are persistent headache, confusion, fever, dizziness, palpitations, visual disturbances, nausea and vomiting. vomiting, difficulty breathing, sweating, cardiac choking, fainting, paralysis, coma, seizures or even death. When this is the case, what should be done is to increase the central volume of the patient, raise the patient's legs, it may be necessary to give physiological saline intravenously. In case of missed dose: You should try to take the dose as soon as you remember. However, if it is too close to the time of the next dose, skip the missed dose and continue with the dosing schedule. You should never take a double dose to make up for a missed dose. In particular, do not skip doses more than 2 times in a row.

4. Undesirable effects of Vasotrate 30

Most adverse reactions are pharmacodynamically related and dose dependent.
Side effects on organ systems in the body:
Cardiovascular system: Low blood pressure, arrhythmia, heart palpitations. Central nervous system: often headaches, dizziness, dizziness, rarely fainting after using the drug. Digestive system: often nausea, rarely vomiting or diarrhea. Musculoskeletal system: Very rarely, Vasotrate 30 users experience muscle pain. Skin: may appear itchy or itchy, rash on the skin. Common side effects
Headache (usually occurs when you start treatment but will go away as you continue treatment) Uncommon side effects
Low blood pressure, dizziness, nausea, rarely fainting after using the drug. Undesirable effects will usually disappear with continued treatment.
During treatment, if you notice any abnormality that is suspected to be caused by the use of Vasotrate 30, you need to consult a qualified pharmacist or treating doctor to be able to handle it. timely and accurate.

5. Vasotrate 30 . drug interactions

During the use of Vasotrate 30 OD, if you have to use one or more other drugs, these drugs may interact with each other, for example, other vasodilators or alcohol will cause resonance. vasodilator effect.
You need to inform the treating doctor or pharmacist for advice about the medicines or health foods you are taking at this time to avoid the occurrence of interactions during the unintended use of Vasotrate 30. would like.

6. Some notes when using Vasotrate 30

6.1. Contraindications of Vasotrate 30 Do not use Vasotrate 30 for people with a history of hypersensitivity or sensitivity to any of the ingredients in the drug. Contraindicated in cases of hypertension with a maximum blood pressure of less than 100 mmHg Do not use the drug for people with glaucoma, increased pressure inside the skull. 6.2. Precautions when using Vasotrate 30 Notes and cautions when treating with Vasotrate 30 OD:
When using the drug to treat people with myocardial infarction or acute congestive heart failure, it is necessary to pay attention to monitoring. individual clinical and hemodynamic status. Use with caution in patients with hypovolemia or hypotension. Do not use Vasotrate 30 mg for pregnant and lactating women. During the use of Vasotrate 30 mg, the patient absolutely adheres to the indications on the therapeutic dose prescribed by the doctor, avoiding increasing or decreasing the therapeutic dose to speed up the treatment time. Before stopping using the drug, you need to consult the treating doctor. should use the drug again. The medicine should be stored in a dry place with moderate humidity and avoid exposure to direct sunlight. Keep away from children's play areas, to avoid the possibility that children may take the wrong medicine without knowing it. Vasotrate 30 OD medicine has the main active ingredient is Isosorbide mononitrate. The drug is indicated for the prevention of angina pectoris caused by coronary artery disease. To ensure the effectiveness of treatment and avoid unwanted side effects, patients need to strictly follow the instructions of the doctor, professional pharmacist.
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