Uses of Enalapril

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Enalapril Stada 5mg is a drug used to treat hypertension, congestive heart failure, prophylaxis in some patients with asymptomatic left ventricular dysfunction, to help slow the development of symptomatic heart failure. . The drug is also indicated for the treatment of patients with left ventricular dysfunction, reducing the incidence of coronary ischemia, myocardial infarction.

1. What are the effects of Enalapril 5mg?

Enalapril belongs to the class of angiotensin-converting enzyme inhibitors, which work by dilating blood vessels to help blood flow more easily. The drug is prepared in the following forms and strengths:
Solution for injection 1.25 mg/ml (1ml, 2ml ampoules); Tablets: Enalapril 5mg, Enalapril 10mg, 20mg and 2.5mg. Enalapril is usually indicated for the treatment of:
Mild to severe hypertension, used alone or in combination with other drugs; Prevention of heart attack, stroke and kidney problems; Prevention of kidney damage caused by diabetes; Treats heart failure and prevents the development of heart failure in people with heart problems (left ventricular dysfunction).

2. How to use Enalapril 10mg


With Enalapril 5mg, 10mg, 20mg... the patient can take it with or without food. It is recommended to keep the medication on even after you feel better, because most people with high blood pressure do not feel any symptoms.
Dosage for adults with hypertension:
Initial dose: Take Enalapril 5mg once a day; Maintenance dose: Take Enalapril 10mg - 40mg per day as a single dose or divided into 2 times a day; Maximum dose: Enalapril 40mg daily as a single dose or in 2 divided doses. In combination with diuretics:
Initial dose: Take Enalapril 2.5mg once daily. If possible, diuretics should be withheld 2 to 3 days before initiating treatment with Enalapril. If necessary, the diuretic can be slowly reintroduced. Dosage for adults with congestive heart failure:
Initial dose: Enalapril 2.5mg once daily; Maintenance dose: Oral Enalapril 2.5 - 40mg per day divided into 2 times; Maximum dose: Enalapril 40mg per day in 2 divided doses. Dosage for adults with left ventricular dysfunction:
Initial dose: Oral Enalapril 2.5mg divided 2 times a day; Maintenance dose: Enalapril 20mg orally in 2 divided doses per day, however, the dose can be doubled if needed. Dosage for children with hypertension:
Children from 20-50kg: Initial dose 2.5mg then adjusted according to response, maximum 20mg/day. Children > 50kg: Initial dose of Enalapril 5mg/day, then adjust dose according to response, maximum use 40mg/day. Enalapril is not recommended for infants and pediatric patients with a glomerular filtration rate less than 30mg/min/1.73m2 To treat high blood pressure, it may take several weeks for the drug to become fully effective. To treat heart failure, it may take weeks to months for the medication to work properly. Tell your doctor if your condition worsens (e.g. blood pressure rises).

3. Enalapril side effects


In some cases, Enalapril 10mg can cause some side effects such as:
Dry cough; Loss of appetite, loss of taste; Nausea, vomiting; Abdominal pain, diarrhea; Headache, dizziness, drowsiness; Paresthesia, dysesthesia; Difficulty sleeping (insomnia); Dry mouth; Mild skin itching or rash. Call your doctor if you have more serious side effects such as:
Want to faint; Abnormal intensity of urination (more or less than usual, or no urination); Swelling, rapid weight gain; Confusion, fatigue in the body, body aches; Loss of appetite, vomiting; thirsty; fever, chills, flu symptoms; pale skin, easy bruising or bleeding; fast, strong, or irregular heartbeat; High blood potassium (slow heart rate, weak pulse, feeling of numbness, muscle weakness) Chest pain; Yellow skin or eyes.

4. Note before taking Enalapril 10mg


Contraindicated to use Enalapril Stada 5mg for the following cases:
People with hypersensitivity to the drug or any ingredient in the drug formula; A history of angioedema caused by ACE inhibitor therapy, patients with hereditary or idiopathic angioedema; Bilateral renal artery stenosis or renal artery stenosis in a person with only one kidney; Aortic stenosis and severe myocardial obstruction; Patients with hypertrophic cardiomyopathy; There is a history of hypotension. Note:
All patients should be regularly checked for renal function before and during ACE inhibitor therapy; Patients with existing kidney disease or on high-dose Enalapril therapy should have their urine protein checked regularly; Patients with collagen disorders such as scleroderma and lupus erythematosus, or in patients receiving immunosuppressive drugs, should have their white blood cell counts regularly checked; Symptomatic hypotension has been reported during the initial phase of ACE inhibitor therapy in patients with heart failure and in patients with sodium loss or dehydration; Because Enalapril Stada 5mg contains Lactose, this drug should not be used for people who are intolerant of Galactose, total Lactase enzyme deficiency or Glucose - galactose malabsorption.

5. Enalapril 5mg . drug interactions


When used with Enalapril 5mg, some drugs are likely to cause interactions such as:
Lithium: there is a possibility of toxicity; Diuretics: excessively lower blood pressure; Potassium supplements: risk of hyperkalemia; Sympathomimetic bronchodilators and non-steroidal anti-inflammatory drugs (NSAIDs): reduce the antihypertensive effect of Enalapril, increase the adverse effects on the kidneys; Oral contraceptives: increased risk of vascular damage, difficulty controlling blood pressure. Above are the uses and special notes when using Enalapril. For details and the correct use, you need to consult your doctor, pharmacist before taking the medicine.

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