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Tulextam has anti-inflammatory, anti-allergic and immunosuppressive effects. The drug is indicated in the treatment of rheumatoid arthritis, psoriatic arthritis and systemic dermatomyositis... Let's learn about the notes when using Tulextam through the article below.
1. What is Tulextam?
Tulextam medicine contains the active ingredient Triamcinolone Acetonide, prepared in the form of an infusion solution containing 80mg/2ml.
Active ingredient Triamcinolone Acetonide is a synthetic glucocorticoid containing Fluor with anti-inflammatory, anti-allergic and immunosuppressive effects. The effect of salt retention, water retention is weaker than that of other Glucocorticoids but lasts longer than Prednisolone. At high systemic doses, Triamcinolone inhibits the adrenocorticotropic hormone from the pituitary gland, and stops the secretion of corticosteroids by the adrenal cortex.
Tulextam is indicated in the following cases:
Symptomatic treatment in rheumatoid arthritis, rheumatoid spondylitis, epicondylitis, psoriatic arthritis and systemic dermatomyositis; Stevens-Johnson syndrome, Pemphigus, severe psoriasis, keloids, angioedema, lichen planus and Hamman-Rich syndrome; In combination with diuretics in the treatment of cirrhosis of the liver, ascites and congestive heart failure; Inflammatory response after dental surgery.
2. Dosage of Tulextam
Tulextam belongs to the group of prescription drugs, so the dose should be prescribed by the doctor based on the patient's condition.
Some recommendations on the dosage of Tulextam are as follows:
Systemic route: Intramuscularly 1 ampoule into the gluteal muscle, the dose can be repeated with an interval of 1 - 5 weeks; Local route: Inject the drug into the synovial space, directly into the tendon sheath, cyst or lesion at a dose of 20mg for small lesions and 40-80mg for large lesions. Do not inject the drug into the site of infection, do not inject intravenously or intradermally. Note: Tulextam dosage shown above is for reference only. The specific dose of medicine for each patient is prescribed by the doctor based on the medical condition.
3. Tulextam side effects
Tulextam can cause some side effects as follows:
Local route: Tendon perforation, bone necrosis, skin redness and skin atrophy at the injection site; Systemic route: Hypertension, edema, peptic ulcer, easy infection, slow wound healing, hyperglycemia causing diabetes or exacerbation of hyperglycemia in diabetic patients, muscle atrophy, myasthenia gravis, muscle fatigue, osteomalacia, osteoporosis, acute adrenal insufficiency upon abrupt discontinuation, insomnia, cataracts and psychosis. Patients should inform their doctor if they experience any unwanted effects during treatment with Tulextam.
4. Note when using
Contraindicated to use Tulextam in the following cases:
Patients with hypersensitivity to Triamcinolone or any component of the drug; Patients with tuberculosis, viral or systemic fungal infections; Patients with idiopathic thrombocytopenic purpura. Caution should be exercised when using Tulextam in the following patients:
Progressive gastric and duodenal ulcers; Hypertension; Congestive heart failure; High risk of venous thrombosis; Thrombophlebitis; Convulsions, kidney failure, diabetes mellitus, antibiotic-resistant infections; Hypothyroidism, pregnant women, lactating women.
5. Drug interactions
Tulextam can interact with drugs Rifampicin, Barbiturates, Ketoconazole, oral contraceptives, Salicylate and Digitalis.
Drug interactions occur that increase the risk of having an effect and reduce the therapeutic effect of Tulextam, so to ensure safety and effectiveness in treating patients, it is necessary to inform the doctor about drugs and foods. were using before taking Tulextam.
Above is all information about Tulextam, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Note, Tulextam is a prescription drug, you absolutely must not buy and treat it at home because you may encounter unwanted side effects.
