This is an automatically translated article.
Hydrocortisone Sodium Succinate is a powder for injection, content of 100mg/vial. To use the drug effectively, learn some information about the uses, dosage and precautions when using Hydrocortisone Sodium Succinate in the article below.
1. Indications for use of Hydrocortisone Sodium Succinate
Hydrocortisone Sodium Succinate is indicated in the following cases:
Hormone replacement therapy in people with adrenal insufficiency; Used for short-term treatment in bone and joint diseases; Osteoarthritis; Rheumatoid arthritis ; Bursitis; Rheumatoid arthritis; Acute and subacute bursitis; Epiglottitis ; Nonspecific acute tenosynovitis; Acute arthritis due to gout; Psoriatic arthritis ; Rheumatoid spondylitis; Diffuse systemic lupus erythematosus; Acute heart inflammation in rheumatic diseases; Systemic polymyositis; Steven-Johnson syndrome; Exfoliative dermatitis; Blisteric dermatitis due to herpes; Severe seborrheic dermatitis; Hormonal disorder . Hydrocortisone Sodium Succinate is a glucocorticoid that crosses cell membranes and binds to specific receptors in the cytoplasm. Hydrocortisone Sodium Succinate is a natural glucocorticosteroid secreted by the adrenal gland, with anti-inflammatory effects, commonly used to treat arthritis, enteritis, bronchitis, skin rashes, rhinitis, allergic eyes. The drug is rapidly absorbed from the gastrointestinal tract and reaches peak concentrations after 1 hour. Hydrocortisone Sodium Succinate reaches maximum plasma concentrations approximately 30 to 60 minutes after intramuscular injection of sterile powder. The drug is metabolized mainly in the liver and excreted in the urine within 24 hours. Therefore, if a sustained high blood concentration is required, it should be injected every 4 to 6 hours.
2. Dosage and how to use Hydrocortisone Sodium Succinate
In case of adrenal insufficiency:
Intramuscular, intravenous or intravenous infusion initially 100mg - 500mg, depending on the severity of the disease, the doctor may prescribe different doses. For children, infants need to reduce the dose accordingly, should not be less than 25mg/day and maximum 15mg/kg/day. In case of osteoarthritis:
For adults, a single dose of 5-25mg, injected in or around the joint, a dose of 125-250mg/day injected deep into the buttock muscle. For children from 7 to 14 years old, the dose is 50 - 75mg. For children from 2 to 6 years old, the dose is 25-50mg. For children from 3 months to 1 year of age, the dose is 25mg, a single dose injected around the joint. For other medical conditions, it is necessary to follow the instructions of the treating doctor when taking the drug.
3. Contraindications when taking the drug
The following cases are contraindicated to use Hydrocortisone Sodium Succinate:
Patients with hypersensitivity or irritation to any ingredient in the drug; Duodenal ulcer or gastritis; Osteoporosis; CKD; Severe hypertension; Chickenpox ; Progressive TB ; Women in the first 3 months of pregnancy; Whole body fungus.
4. Hydrocortisone Sodium Succinate drug interactions
Oral antidiabetic drugs; Anticoagulants, salicylates; Diuretic.
5. Side effects when taking the drug Hydrocortisone Sodium Succinate
Joint pain; Hypertension ; Adrenal cortex insufficiency; Osteoporosis ; Pathological fractures; Spinal fracture with spinal cord compression; Aseptic necrosis; Increased stomach acid; Gastric and duodenal ulcers; Stomach bleeding ; Pancreatitis; Esophagitis; Stomach perforation; Electrolyte disorders: sodium retention,...; Congestive heart failure; Hypokalemia; Slow wound healing; Hemorrhagic bruises; Psychosis; Epileptic; Menstrual disorders; Cushing's syndrome; Decreased pituitary gland, adrenal gland; Diabetic disorders; Cataracts ; Increased eyeball pressure, protrusion; Decreased immune system. Hydrocortisone is a natural glucocorticosteroid secreted by the adrenal gland, with anti-inflammatory effects, used to treat arthritis, enteritis, bronchitis, skin rash, rhinitis, allergic eye inflammation. To ensure safety for health and maximize the effectiveness of treatment, you need to use Hydrocortisone is a glucocorticosteroid according to the manufacturer's instructions.
