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Trimazon 480 is a broad spectrum bactericidal antibiotic. Medicines are often prescribed to treat bacterial infections.
1. What is Trimazon 480?
Trimazon 480 is an antibiotic belonging to the group of anti-parasitic, anti-infective, antifungal, and antiviral drugs. The drug contains the main ingredients including:Active ingredient Sulfamethoxazole 400mg; Trimethoprim 80mg; Other excipients are sufficient. Trimazon 480 is prepared in the form of tablets and packaged in a box of 10 blisters, each blister contains 10 tablets of 480mg.
Effects of Trimazon 480:
Trimazon 480 is a combination of 2 main active ingredients, Sulfamethoxazole and Trimethoprim in the ratio 1:5. This combination creates a synergistic effect, useful in enhancing the bactericidal effect and reducing drug resistance. Sulfamethoxazole is an antibiotic belonging to the Sulfamide group, with a chemical structure similar to para aminobenzoic acid (PABA). The drug competes with PABA and inhibits the phase 1 of bacterial folic acid synthesis, thereby having a bactericidal effect. The active ingredient Sulfamethoxazole has a broad antibacterial spectrum against Gram (-) and Gram (+) aerobic bacteria such as Staphylococcus, E. coli, Streptococcus, Salmonella, Legionella pneumophila, Enterobacter,... However, this active ingredient is resistant to some bacteria such as Enterococcus, Campylobacter and anaerobic bacteria. Trimethoprim is an antibiotic with bacteriostatic action. The mechanism of action of the drug is to inhibit the enzyme dihydrofolate - reductase of bacteria. Trimethoprim can be used alone or in combination with the active ingredient Sulfamethoxazole, depending on the specific case.
2. What diseases does Trimazon 480 treat?
The use of Trimazon 480 is to kill many types of bacteria. The spectrum of action of Trimazon is very broad, including E. coli, Enterobacter sp, Klebsiella sp. Trimazon 480 is commonly used to treat infections caused by gram-negative bacteria, especially susceptible to gonococcal disease, uncomplicated acute urinary tract infections and pneumonia caused by Pneumocystis carinii.
Drug Trimazon 480 is often indicated in cases, including:
Treatment of urinary tract infections. Treatment of respiratory tract infections: Bronchitis, pneumonia, sinusitis,... Treatment of digestive tract diseases: Bacillary dysentery. Treatment of infections caused by microorganisms sensitive to the components of the drug Trimethoprim and Sulfamethoxazole. Treatment of exacerbations in people with chronic bronchitis.
3. Usage and dosage of Trimazon 480
Dosage below is for reference only, as recommended by the manufacturer. You need to take the medicine exactly as prescribed by your doctor. The reason is that the effectiveness of the drug depends on the tolerability of the drug as well as the body of each person.
Treatment of infections related to the urinary tract: Take 1 to 2 tablets / time, 2 times a day, using the drug for a period of 10 days. Treatment of infections related to the upper and lower respiratory system: Take 1 to 2 tablets / time, 2 times a day, using the drug for a period of 10 days. Treatment of digestive tract disorders caused by bacteria: Take 1 to 2 tablets / time, 2 times a day, using the drug for a period of 5 days. How to use the drug:
The therapeutic effect of Trimazon 480 is not affected by food. You can use the drug before or after a meal, depending on the doctor's prescription. You should actively monitor your health status and inform your doctor about your health status and healing level.
4. In case of forgetting/overdose of medicine
In case of overdose: Some manifestations of overdose include digestive disturbances, loss of appetite, nausea, vomiting, headache feeling. When using an overdose, you need to immediately contact the treating doctor for timely handling measures.
In case of missed dose: You should take the missed dose as soon as you remember. However, if it is close to the time for your next dose, skip that dose and continue taking it as scheduled. You need to be absolutely careful not to take together or double the treatment dose.
5. Undesirable effects of the drug Trimazon 480
Besides the effects of the drug, when treated with Trimazon 480, there may also be some unwanted effects such as:
Digestive disorders such as nausea, vomiting, abdominal pain and bowel movements. Affects hearing or hearing ability. Hematologic disorders: leukopenia and neutrophils, macrocytic anemia due to folic acid deficiency, thrombocytopenia. Some other undesirable effects may be encountered such as skin reactions, tinnitus, erythema multiforme or Stevens - Johnson syndrome, Lyell. You should immediately consult a doctor or pharmacist if you experience any unusual symptoms that are suspected to be caused by the use of this medicine.
6. Interactions of Trimazon 480
Trimazon 480 when used with some drugs can increase effects, cause high toxicity, increase unwanted effects or reduce effects. Some groups of drugs should be noted because they cause drug interactions when used together with Trimazon 480:
Thiazide diuretics. Group of drugs to treat hypoglycemia. Some other drugs: Warfarin, Phenytoin, Methotrexate, Pyrimethamine, Cyclosporin, Indomethacin.
7. Some notes when using Trimazon 480
Contraindications of Trimazon 480:
People who are sensitive or sensitive or have a history of hypersensitivity to any of the ingredients in Trimazon 480. Contraindicated to use the drug for pregnant women due to possible effects affect the health of the fetus. Contraindicated in people with severe renal impairment because the drug excreted and accumulated can be toxic to the kidneys. Notes and cautions when using Trimazon 480:
Attention and precaution for some subjects: people with hematological disorders, lactating women, the elderly, people with G6PD enzyme deficiency, folate deficiency, people with kidney failure . Do not use Trimazon 480 drugs that have expired, the medicine shows signs of mold, bleeding,... During the treatment period with Trimazon 480, if any signs of drug reaction occur, you should immediately seek medical attention. medical facility for timely and proper examination and treatment by a doctor. Note for pregnant and lactating women:
Trimazon 480 is contraindicated for use in pregnant women because the ingredients of the drug can cross the placental barrier, so it may have adverse effects on the fetus. pediatric. Due to the composition of the drug Trimazon 480 has the ability to inhibit the metabolism of folic acid and increase the risk of anemia in pregnant women. Trimazon 480 should be used with caution in lactating women. The reason is that the drug can be excreted in milk and children are very sensitive to unwanted effects of the drug. How to store the medicine:
Store the medicine in a cool, dry place, the room temperature does not exceed 30 degrees Celsius. Avoid leaving Trimazon 480 in humid, high humidity, unsanitary places. Avoid leaving Trimazon 480 in a place exposed to direct sunlight or high intensity light. Above is information about uses, dosage and precautions when using Trimazon 480. To ensure the safety of your health and maximize the effectiveness of treatment, you need to take the medicine exactly as directed by your doctor.
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