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Transat Tablets 500 mg is a prescription medicine used in certain conditions related to bleeding. So what is Transat Tablets 500 mg and how to use it?
1. What is Transat Tablets 500 mg?
Transat Tablets 500mg belongs to the group of drugs that act on the blood, the drug is prepared in the form of film-coated tablets with the main ingredient in each tablet is Tranexamic acid 500mg.Tranexamic acid inhibits fibrinolysis by inhibiting plasminogen plasminogen activation. Transat Tablets 500mg is indicated for the short-term treatment of bleeding conditions or bleeding risk associated with increased fibrinolysis. Increased fibrinolysis occurs in the following cases:
After surgery to remove the prostate and bladder. Menorrhagia Nosebleeds Surgery to remove the cervix. Anterior hemorrhagic trauma. Hereditary angioedema. Control bleeding during tooth extraction in patients with hemophilia. Transat Tablets 500mg is contraindicated in the following cases:
People with hypersensitivity to tranexamic acid or any other component of the drug. Severe renal failure Thromboembolism History of arterial or venous thrombosis. History of seizures
2. Dosage and how to take Transat Tablets 500mg
Transat Tablets 500mg is used orally. The dose of Transat Tablets 500mg should be according to the doctor's prescription, the reference dose is as follows:
Treatment of local fibrinolysis is recommended using a dose of 15-25mg/kg x 2-3 times/day. Specific cases are as follows: Prostatectomy: Prophylaxis and treatment of bleeding in high-risk patients should be started before or immediately after surgery with a dose of 2 tablets x 3-4 times. /day. Then continue taking the drug until no more gross hematuria. Menorrhagia : Use 2 tablets / time x 3 times / day, when necessary, can be used for up to 4 days. If heavy menstrual bleeding occurs, the dose should be increased. The total dose of Transat Tablets 500mg in 1 day should not exceed 4g (8 tablets). Transat Tablets 500mg should not be used until the patient begins to have menorrhagia. Recurrent nosebleeds: Use dose of 2 tablets/time x 3 times/day for 7 consecutive days. Cervical ablation: Use a dose of 3 tablets / time x 3 times / day. Anterior hemorrhagic trauma: Use dose of 2-3 tablets/time x 3 times/day. Dosage is based on 25 mg/kg body weight. Treatment of hereditary angioedema: For patients who are aware of the onset of the disease, use the appropriate therapeutic dose of 2 - 3 tablets/time x 2 - 3 times/day for several days. For other patients being treated continuously with the above dose. Hemophilia: To control bleeding when performing tooth extraction in patients with hemophilia, use a dose of 2-3 tablets/time every 8 hours. Renal failure Serum creatinine from 120-249 μmol/l using a dose of 15 mg/kg body weight, twice daily. Serum creatinine from 250 - 500 μmol/l using a dose of 15 mg/kg body weight, once a day. Symptoms that may appear when using an overdose of Transat Tablets 500mg include: Nausea, vomiting, orthostatic hypotension. Currently, there is no specific remedy for tranexamic acid overdose. If poisoned by taking an overdose of Transat Tablets 500mg, it is necessary to induce vomiting, gastric lavage, and use activated charcoal. At the same time, it is recommended to maintain fluid supplementation to promote renal drug excretion and use necessary symptomatic and supportive treatment measures.
3. Side effects of Transat Tablets 500mg
During the use of Transat Tablets 500mg, you may encounter some side effects of the drug. Rare side effects of Transat Tablets 500mg include:
Blood disorders. Retinal/arterial occlusion. Thromboembolism. Allergic skin reactions. Very rare side effects of Transat Tablets 500mg include:
Hypersensitivity reactions including anaphylaxis. Arterial or venous thrombosis at any site. Nausea, vomiting and diarrhea, these symptoms usually disappear when the dose is reduced. In the process of using Transat Tablets 500mg, if you notice any unusual symptoms, you should immediately notify your doctor or go to the nearest medical facility for timely support.
4. Interaction of Transat Tablets 500mg with other drugs
Do not use Transat Tablets 500mg at the same time with estrogen, because it can cause more thrombosis. Caution should be exercised when Transtat Tablets 500mg is co-administered with other hemostatic agents. The antifibrinolytic effect of Transat Tablets 500mg is antagonized by thrombolytic agents. Concomitant administration of Transat Tablets 500mg with oral tretinoin may cause thrombosis in the microvasculature. The above are the important uses when using Transat Tablets 500mg, before using, patients should consult a specialist doctor if they have any further questions, they can discuss directly with the doctor for advice. suitable question.
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