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Tormeg 20mg drug with the main ingredient is atorvastatin, indicated in the case of preventing cardiovascular diseases and treating hyperlipidemia. So how should Tormeg 20 be used?
1. What is tormeg 20?
Atorvastatin calcium, a synthetic lipid-lowering agent and 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor. A precursor of sterols, including cholesterol. Cholesterol and triglycerides circulate in the blood as part of a lipoprotein complex that includes HDL (high-density lipoprotein), IDL (intermediate-density lipoprotein), LDL (low-density lipoprotein), and VLDL (very low-density lipoprotein). , Triglycerides (TG)High plasma concentrations of total cholesterol, LDL- cholesterol , apolipoprotein B promote atherosclerosis in humans and a risk factor for the development of cardiovascular diseases, while increasing concentrations HDL-Cholesterol reduces the risk of cardiovascular disease
Tormeg reduces Total cholesterol, LDL- cholesterol and apolipoprotein B in patients with hypercholesterolemia Tormeg also reduces VLDL - Cholesterol and Triglycerides and increases production HDL - Cholesterol and apolipoprotein A - 1 in patients with only elevated Triglycerides
Tormeg is synthesized and metabolized in the liver, rapidly absorbed after oral administration. hepatic or extrahepatic Mean half-life The average of Tormeg in human plasma is about 14 hours.
2. Indications to use Tormeg 20
Dyslipidemia:
Tormeg helps reduce the concentration of "bad" lipid components (LDL-cholesterol, triglycerides) and increase "good" lipids (HDL-Cholesterol) in the blood of patients.
Prevention of cardiovascular events:
In people with dyslipidemia, there are no obvious clinical manifestations of coronary heart disease. Tormeg 20 helps to reduce the risk of myocardial infarction, angina,... In patients with dyslipidemia who have had clinical manifestations of coronary artery disease, including myocardial infarction, and previous angina . Tormeg 20 helps reduce the risk of stroke and death. Prevention of cardiovascular events in people with diabetes
Tormeg 20 helps reduce the concentration of "bad" lipids in the blood, preventing the risk of coronary heart disease in diabetics with hypercholesterolemia.
Reduced risk of advanced coronary atherosclerosis
Tormeg 20 is indicated in hyperlipidemic patients with clinical manifestations of coronary artery disease, such as prior myocardial infarction. Helps slow the progression of cardiovascular disease.
3. Contraindications to Tormeg 20
Tormeg 20 is contraindicated in the following cases:
Progressive liver disease with unexplained persistent elevation of liver enzymes. Allergy to ingredients of the drug. Pregnant women. Women are breastfeeding. Use with caution
Do a liver enzyme test before starting treatment with Tormeg 20 . Dose reduction or discontinuation is recommended when ALT or AST increases >3 times the upper limit of normal. Consider monitoring for creatine kinase (CK), which is a muscle function test in: Impaired renal function, hypothyroidism, history of hereditary myopathy, history of myopathy due to previous statin or fibrate use . If CK test results are > 5 times the upper limit of normal, treatment with Tormeg 20 should not be initiated. There is an increased risk of muscle damage when Tormeg 20 is used concurrently with the following drugs: Gemfibrozil, other fibrate-lowering agents, high-dose niacin (> 1g/day), colchicine. May increase HbA1c and fasting serum glucose levels. Safe to use in children 10-17 years of age with familial hypercholesterolemia. Increased risk of myopathy in the elderly (>65 years), should be used with caution.
4. Dosage and usage
How to use
Oral medicine. Tormeg 20 can be taken as a single dose at any time of the day, with or without food. Dosage
Non-hereditary hyperlipidemia and mixed dyslipidemia:
Initial dose: 10mg - 20mg/time/day. Patients requiring a large reduction in LDL-C (greater than 45%) starting at 40 mg once daily. Maximum dose: 80mg/time/day. Hereditary hypercholesterolemia in pediatric patients (10-17 years old)
Initial dose: 10mg/day. Maximum dose: 20mg/day Hereditary hypercholesterolemia
Initial dose: 10-80mg/day. Combination therapy with other lipid-lowering agents.
5. Side effects of the drug Tormeg 20mg
Rare:
Myalgia. Jaundice, yellow eyes, dark urine - these can be signs of liver damage. A red rash on the skin, especially on the palms or soles of the feet. Abdominal pain in epigastrium, pain spreading to the back. Cough, feeling short of breath, and weight loss. Anaphylaxis . Other side effects:
Feeling nauseous Stomach bloating, indigestion Headache Pain in back and joints Nosebleeds Sore throat Runny, stuffy nose or sneezing. Constipation Diarrhea Above is important information about the drug Tormeg 20. Knowing the dosage, usage, and effects will help the treatment be more effective.
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