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Tolura 40mg is a drug used in the treatment of a number of cardiovascular diseases. So what is Tolura 40mg drug, how does it work and how to use it?
1. Uses of Tolura 40mg
Tolura 40mg drug belongs to the group of Angiotensin II receptor antagonists, the drug is made in the form of tablets with the main ingredient in each tablet is Telmisartan 40mg.
Telmisartan is a specific antagonist of the angiotensin II receptor (AT1), which binds selectively to this receptor. Thus, it has a blood pressure lowering effect. Telmisartan has no affinity for receptors other than AT1, neither inhibits plasma renin nor inhibits ACE.
Tolura 40mg is indicated in the following cases:
Idiopathic hypertension in adults. Prevention of cardiovascular disease and death: The drug has the effect of reducing the incidence of cardiovascular disease in the elderly, especially patients with atherosclerosis, patients with type 2 diabetes who have had damage to target organs. Tolura 40mg drug in the following cases:
People who are sensitive to any ingredient of the drug. Pregnant women in the second and third trimesters of pregnancy. Using Tolura 40mg in the second and third trimesters of pregnancy will cause fetal toxicity such as amniotic fluid deficiency, renal function decline, skull ossification delay, neonatal toxicity such as hyperkalemia, low blood pressure. , CKD. Severe liver failure. Bile duct obstruction. Are using Aliskiren in patients with diabetes or kidney failure. Use caution when using Tolura 40mg for the following cases:
Kidney failure Kidney transplant. Have other cardiovascular diseases. Increased blood potassium. Symptomatic hypotension. Liver failure. Renal artery stenosis. Diabetes. Primary aldosteronism.
2. Dosage and how to use Tolura 40mg
How to use Tolura 40mg drug as follows:
Tolura 40mg drug is used orally. The medicine can be taken with water or other non-alcoholic beverages. The time to take the drug does not depend on the meal, it can be taken before or after a meal. Only remove the pill from the blister just before taking it to prevent the tablet from getting hygroscopic. Dosage of Tolura 40mg should be according to the doctor's prescription. Dosage recommendations are given for specific cases as follows
Treatment of essential hypertension: Use 1 tablet once a day. There are some patients who can respond well to a dose of 20mg once a day. The maximum dose of Tolura 40mg is 2 tablets / time / day. Tolura 40mg can be used in combination with thiazide diuretics. The maximum antihypertensive effect is achieved after 4-8 weeks of treatment with Tolura 40mg, so special care should be taken if the dose is to be increased. Prevention of cardiovascular disease and death: Use 2 tablets/time/day. It is recommended that blood pressure be monitored at the start of treatment and, if necessary, the dose of Tolura 40 mg can be adjusted to achieve a lower blood pressure. Mild and moderate renal impairment does not require dose adjustment. For patients with severe renal impairment or on hemodialysis, experience with Tolura 40 mg is limited, and a starting dose of 20 mg once daily is recommended. For patients with mild and moderate hepatic impairment, the maximum dose is 1 tablet/time/day. Children under 18 years: The safety and effectiveness of Tolura 40mg have not been established. If you forget a dose of Tolura 40mg, take it as soon as you remember. However, if you remember it is almost time for your next dose, take your next dose as scheduled. Never take a double dose to make up for a previously forgotten dose.
Overdosage with Tolura 40mg, you may experience the following symptoms:
Lower blood pressure Tachycardia Slow heart rate Increased serum creatinine Acute kidney failure Dizziness If you overdose and appear side effects disadvantage, you need to be immediately taken to the nearest medical facility for reasonable and timely treatment.
3. Tolura 40mg . side effects
A common side effect of Tolura 40mg in patients being treated for cardiovascular disease is the possibility of low blood pressure.
Uncommon side effects of Tolura 40mg include:
Urinary tract infections Anemia Hyperkalemia. Insomnia Depression. Fainting Dizziness Slow heartbeat Low blood pressure Postural hypotension Shortness of breath, cough, upper respiratory tract infections such as pharyngitis, sinusitis, colds. Stomach upset Cramps. If you experience any side effects of Tolura 40mg, please inform your doctor immediately or go to the nearest medical facility for timely treatment.
4. Drug interaction Tolura 40mg with other drugs
Drug interactions Tolura 40mg need to be careful when taking the combination:
Using Tolura 40mg in combination with Digoxin will increase the concentration of digoxin in the blood plasma. The use of Tolura 40mg together with potassium-sparing diuretics and potassium supplements will reduce the effect of these drugs, so regular monitoring of serum potassium is required. Co-administration of Tolura 40mg with Lithium will increase the serum lithium concentration. Using Tolura 40mg together with corticosteroids will reduce the antihypertensive effect. Using Tolura 40mg with other antihypertensive agents may increase the antihypertensive effect. With all the information about Tolura 40mg medicine, hopefully, it will help you know how to use, use and store it properly, Taking the drug for the right purpose always brings the best treatment results.
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