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Thenadin is an H1 antihistamine with the main ingredient Alimemazine tartrate 5mg. Alimemazine is an active ingredient with strong anti-histamine and serotonin effects, helping sedation, cough relief, anti-emetic.
1. What is Thenadin?
Thenadin contains the main ingredient is Alimemazine tartrate 5mg.
Histamine - a chemical found in certain cells of the body - causes allergy symptoms such as runny nose and sneezing. When you are allergic to a specific substance, such as food or dust, your immune system mistakenly thinks that the substance is harmless but is actually harmful to the body.
In an effort to protect the body, the immune system initiates a chain reaction that prompts certain cells of the body to release histamine and other chemicals into the bloodstream. The histamine then acts on the eyes, nose, throat, lungs, skin, or gastrointestinal tract, causing allergy symptoms.
Of which, Alimemazine is an antihistamine. Alimemazine has an H1-antihistamine effect by competing with histamine for the H1-histamine receptors. Antagonists with most of the effects of histamine H1 including urticaria, pruritus. In addition, Alimemazine also has sedative, antitussive, antiemetic effects.
2. Indications of Thenadin 5mg The drug is indicated for use in the following cases:
Insomnia; Frequent vomiting in children; Respiratory allergies (rhinitis, runny nose, sneezing); Skin allergies (urticaria, itching); Liquor grade ; Cough a lot at night.
3. How to take Thenadin 5mg
How to use: Take the drug by mouth, use after eating.
Dosage:
Treatment of urticaria, itchy papules: Adults: 10 mg x 2-3 times/day; Elderly people should reduce the dose: 10mg x 1-2 times / day; Children > 2 years old: 2.5 - 5mg x 1-2 times/day. Anti-histamine, antitussive, antiemetic: Adults: 5mg x 3 - 4 times/day; Children > 2 years: 0.5 - 1 mg/kg/day. Use to induce sleep: Adults: 5 - 20 mg, taking the drug before going to bed; Children over 2 years old: 0.25 - 0.5 mg/kg/day, taken at bedtime. 4. Contraindications of Thenadin 5mg Thenadin 5mg is contraindicated in the following patients:
Liver and kidney dysfunction, Parkinson's disease, epilepsy, hypothyroidism, pheochromocytoma, gland enlargement prostate, myasthenia gravis; Hypersensitivity to phenothiazines or a history of narrow-angle glaucoma; In case of overdose due to use of barbiturates, opiates and alcohol; Agranulocytosis, when there is a previous episode of agranulocytosis; Children under 2 years old; Women who are pregnant and breastfeeding. 5. Side effects of Thenadin 5mg Common: Fatigue, headache, dizziness, dry mouth, thick phlegm; Uncommon: Constipation, urinary retention, eye accommodation disorder; Rare: Leukopenia, agranulocytosis, increased heart rate, hypotension, hepatitis, cholestatic jaundice; Parkinson's tremor, extrapyramidal symptoms, restlessness, acute dystonia, tardive dyskinesia; damage teeth and enamel; risk of respiratory arrest, even sudden death in young children. 6. Precautions when taking Thenadin 5mg Be careful when using Thenadin 5mg for the elderly, especially when the weather is very hot or very cold (because the drug has a risk of increasing or lowering temperature), making the elderly very susceptible to hypothermia. orthostatic blood pressure; The drug may interfere with skin tests for allergens; Avoid taking the drug with alcohol or other CNS depressants. 7. Drug interactions Some drugs when used together increase the effect of Thenadin 5mg such as alcohol, antihypertensive drugs, Barbituric sleeping pills and other sedatives; Thenadin 5mg antagonizes the therapeutic effects of Amphetamine, Conidin, levodopa, Guanethidine, Adrenalin; Antacids, Parkinson's drugs, lithium prevent the absorption of Alimemazine In summary, Thenadin 5mg contains the main active ingredient is Alimemazine, belongs to the group of antihistamines. The drug is mainly used in the treatment of allergies and insomnia. To ensure safety when using the drug, patients should consult their doctor before using.
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