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Usarderon belongs to the group of emergency and detoxifying drugs, which treat conditions with excess iron in the body. So what exactly is Usarderon drug and in what cases is it indicated?
1. What is Usarderon?
Usarderon has the active ingredient Deferiprone 500mg and other excipients, just enough for 1 tablet for users. The drug is prepared in the form of hard capsules, packed in boxes, each box contains 1 bottle of 60 tablets.
2. Uses of the drug Usarderon
2.1 Uses - indication of Usarderon drug Usarderon drug is used to treat iron excess in the body, mainly in patients with Thalassemia.
2.2 Contraindications Usarderon drug Usarderon drug is contraindicated for use in the following cases:
People with a history of recurrent neutropenia. People with a history of agranulocytosis. Women who are pregnant or are breastfeeding. Note: Contraindications need to be understood as absolute contraindications, ie not for any reason that contraindications can be used flexibly.
3. Usage and dosage of the drug Usarderon
3.1. How to take Usarderon Drug Usarderon is prepared in the form of hard capsules that should be taken orally. It is recommended that the patient should take the drug with a sufficient amount of water, use filtered water, should not use other liquids such as carbonated soft drinks, milk, wine, beer.
3.2. Usarderon Dosage For the treatment of patients with Thalassemia: The initial and maintenance dose should only be given to this subject by a truly experienced physician. Usual dose: Use 25mg/kg body weight, use 3 times a day (not to exceed 75mg/kg/day). Not recommended to use doses above 100mg/kg/day: may increase unwanted side effects, harm the body. If the user uses a dose higher than 2.5 times the maximum recommended dose for a long time, it may cause neurological disorders. Use for children from 6 to 10 years old: There are no data on the dosage of Usarderon for this population. Note: The dose used depends on the weight and severity of the disease of each person, so before using the drug, the patient should be examined and prescribed by the treating doctor.
In case of missed dose: Users should take it as soon as they find out if the time is far from the next dose. Otherwise, skip the missed dose and continue with the next dose at the prescribed time. Never use double the number of doses to make up for the forgotten dose, to avoid causing an overdose.
In case of overdose: When it is discovered that they have overdosed and found unusual symptoms, the patient should immediately notify the treating doctor or the person in charge of medical expertise. If there are symptoms that require emergency care, the patient should immediately call 911 or go to the local medical facility where they live. When traveling, family members should bring medical records, prescriptions, and drugs that the patient is taking so that the diagnosis and treatment process can take place more quickly.
4. Usarderon side effects
In addition to the main effects that Usarderon brings, users may also experience some unwanted side effects such as:
The most serious side effect: Agranulocytosis. Mild side effects: Neutropenia, diarrhea. These symptoms are mostly very mild and transient. Effects on the digestive system: Common at the beginning of treatment and will disappear in the next few weeks without stopping use of the drug. Causes elevation of serum liver enzymes: These elevations are usually mild, transient, and return to normal upon dose reduction or discontinuation. Note: When users detect the above symptoms or other symptoms not mentioned in the instruction sheet, they should immediately notify the doctor for instructions and timely handling.
5. Interaction with Usaderon
Currently, there are no reports of interactions between Usarderon and other drugs. However, there are some interactions that have been noted and should be noted such as:
Deferiprone and aluminum-containing drugs should not be used in combination, because the active ingredient Deferiprone can bind to metal cations. Deferiprone and vitamin C should be used with caution. Usarderon should not be combined with agranulocytosis and neutropenia.
6. Some notes when using Usarderon drug
When using the drug, users need to have their neutrophil counts checked regularly, it is recommended that every week. If the patient develops an infection during treatment, the drug should be discontinued and the neutrophil count closely monitored. When symptoms of infection such as fever, sore throat or flu-like symptoms occur, you should immediately notify your doctor for treatment. The drug should not be used to treat people with neutropenia. Use caution when using Usarderon for patients with liver failure, kidney failure. For people who are intending to become pregnant or are pregnant, do not use it because it can cause genetic mutations, teratogenicity. The drug is not recommended for use in nursing mothers, should discontinue the drug or discontinue nursing. In summary, Usarderon belongs to the group of emergency and detoxifying drugs, effective in treating conditions with excess iron in the body. Because this is a prescription drug, patients should not use it on their own, but need to contact a specialist directly to get an appropriate prescription to ensure safety for health.