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Usarclopi 75 - cardiovascular drug, taken according to the instructions. To ensure safe use of Usarclopi 75, avoid interactions and side effects. Let's find out more clearly what Usarclopi 75 does, how to use it, how to use it, warnings, ... right here.1. What is Usarclopi 75?
Usarclopi 75 belongs to the group of cardiovascular drugs, with a prescription.Usarclopi 75 has the main active ingredient Clopidogrel (in the form of Clopidogrel bisulfate) 75mg. In addition, there are a number of other excipients in Usarclopi 75 as announced by the manufacturer.
Usarclopi 75 is prepared in the form of film-coated tablets, packed in a box of 3 blisters x 10 tablets. The medicine box is blue, the drug name is printed in yellow, and the content is printed in green with white border.
What does Usarclopi 75 do? Usarclopi 75 has the main active ingredient Clopidogrel 75mg - a selective inhibitor of Adenosine diphosphate (ADP) on its receptor in platelets.
This induces ADP-mediated activation of the GlycoproteinGPIIb/IIIa complex, causing inhibition of platelet aggregation. Biochemistry of Clopidogrel - the main ingredient in the drug Usarclopi 75 has a particularly important role with the inhibition of platelet aggregation. However, the active metabolite of Usarclopi 75 was not isolated. The drug acts by irreversibly altering the platelet ADP receptor. As a result, platelets that bind Clopidogrel - the main component of Usarclopi 75 will have an effect on the later stages of platelets.
Usarclopi 75 is absorbed immediately after oral administration. The metabolite reached peak plasma concentrations after repeated dosing approximately 1 hour after oral administration. Usarclopi 75 is distributed by reversible binding to plasma proteins and is metabolized in the liver, and is excreted in the feces and urine.
2. Indication Usarclopi 75
Usarclopi 75 is used in the following cases:2.1. Primary prevention of thromboembolic disorders
Includes:Prevention of myocardial infarction ; Stroke prevention ; Prophylaxis of peripheral artery disease.
2.2. Secondary prevention and control
Usarclopi 75 is used for the following subjects:Atherosclerotic stroke; Recent myocardial infarction; Peripheral arteries identified; What are the uses of Usarclopi 75? Usarclopi 75 is effective for the prevention and control of the conditions in the indication.
3. Dosage - How to take Usarclopi 75
Usarclopi 75 is administered orally. Usarclopi 75 can be taken with or without meals. The dosage of Usarclopi 75 according to the manufacturer's recommendations is to use according to the medical condition. Specifically:History of atherosclerosis: It is recommended to take 1 tablet/day; Prophylaxis of thromboembolic disorders: The recommended dose is 1 tablet/day; Acute coronary syndrome: Use a starting dose of 300mg and use a single dose. Adjust dose to 75mg/day as maintenance dose; In special populations such as patients with renal impairment, use of Usarclopi 75 does not require dose adjustment.
4. Contraindications Usarclopi 75
Drugs Usarclopi 75 should not be used for:Allergy, hypersensitivity to any ingredients, excipients in Usarclopi 75; History of gastrointestinal bleeding; History of intracranial hemorrhage; Liver failure (severe); ... The subjects in the contraindications section should not use the drug Usarclopi 75 to ensure safety.
5. Usarclopi 75 . interaction
As recommended, Usarclopi 75 may interact with a number of other drugs including:Aspirin ; Heparin; Warfarin ; Omeprazole; Esomeprazole; Fluvoxamine; Fluoxetine; Moclobemide; Voriconazole; Fluconazole ; Ticlopidine; Ciprofloxacin ; Cimetidine; Carbamazepine; Oxcarbazepine; Chloramphenicol; ... Inform the doctor about the current / used drugs before taking Usarclopi 75 to avoid drug interactions.
6. Usarclopi 75 . side effects
The active ingredient Clopidogrel in Usarclopi 75 is generally easy to absorb. However, when drinking you may also experience some unwanted effects including:Diarrhea; Stomachache; Undigested; Flatulence; Nausea; Skin allergies (erythema, itching); Chest tightness; Epistaxis ; Gastrointestinal bleeding; Stomach ulcers; Decrease in neutrophils; Thrombocytopenia; Aplastic anemia ; Kidney disease; Loss of taste; Acute arthritis; Intracranial hemorrhage; Bleeding in the eye; ... The side effects of taking Usarclopi 75 vary from person to person. Therefore, you should notify your doctor when you encounter it for treatment.
7. Warnings and Precautions for Usarclopi 75
The manufacturer also gives some warnings and cautions when using Usarclopi 75 as follows:Be careful in the group of bleeding subjects such as trauma, pathology, surgery, ..; If surgery must stop using Usarclopi 75 before the day of surgery; Subjects with bleeding-related lesions; Severe liver failure; Poor metabolism due to CYP2C19; ... The group of subjects mentioned above should be used with caution. Healthcare professionals should warn patients before taking Usarclopi 75.
8. Pregnant women, nursing mothers, driving and operating machines use Usarclopi 75
There are no studies in pregnant subjects using Usarclopi 75, so it should be used with caution, only used when absolutely necessary; There are no studies on whether Usarclopi 75 is excreted in human milk. But to be on the safe side, stop Usarclopi 75 while breastfeeding; Usarclopi 75 does not affect the group of drivers and machine operators, so it can be used.9. Overdose and treatment Usarclopi 75
Long-term overdose of Usarclopi 75 can cause bleeding and bleeding complications. When overdosage is toxic, it often causes clinical symptoms including:Vomiting; Tired; Shortness of breath ; Hemorrhage; ... Quickly go to the medical facility when there is an overdose of Usarclopi 75 for intervention.
10. Store Usarclopi 75
Usarclopi 75 stores well at room temperature.What does Usarclopi 75 do? Usarclopi 75 is used in the control and prevention of cardiovascular problems in indications. Usarclopi 75 is used by prescription, requires guidance and advice from a doctor / pharmacist.
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