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Metrothabi is an antibiotic used in the treatment of certain types of infections because of its ability to prevent the growth of bacteria and parasites that are harmful to health. Referring to medication information is essential to help patients get the best results during treatment.
1. What is the effect of Metrothabi?
The main ingredient of this medicine is Metronidazol 250 mg. So with the above ingredients, does Metrothabi have any effect?
According to experts, Metronidazol contained in Metrothabi promotes good bactericidal ability on anaerobic bacteria (this is bacteria that usually grows in an oxygen-free environment). Specifically, anaerobic bacteria appear in many locations in the human body, in which are concentrated in the oral cavity and gastrointestinal tract,...
In addition, metronidazole is also highly effective on some microorganisms. protozoan such as flagellate (T. vaginalis), amoebic dysentery (E. histolytica) and the most serious is Giardia lamblia,...
2. Indications and contraindications Metrothabi
2.1. Indications Metrothabi is indicated for patients infected with Trichomonas vaginalis, Entamoeba histolytica (including acute intestinal and liver abscess), Dientamoeba fragilis, Dracunculus medinensis and notably Giardia lamblia. Patients with severe infections caused by susceptible anaerobic bacteria such as intra-abdominal infections, gynecological infections, skin infections, central nervous system infections, bacteremia and endocarditis. Concomitant use with neomycin or kanamycin for the prevention of infection in colorectal surgery and gynecological surgery. Metrothabi is used in patients with acute ulcerative necrotizing gingivitis, periodontal gingivitis and other dental infections caused by anaerobic bacteria. Used together with some drugs to treat peptic ulcers caused by Helicobacter pylori. 2.2. Contraindications Metrothabi should not be used in patients with a history of hypersensitivity to metronidazole or other nitro-imidazole derivatives.
3. Dosage and how to take Metrothabi
Metrothabi is prepared in the form of tablets with the time of use with or after meals with the following reference doses:
For diseases caused by Trichomoniasis: Use Metrothabi a single dose of 2 g, or use 7 days, every day 3 times with a dose of 250mg/time. Women with this disease need to pay attention to treating both their partners. For acute amoebic dysentery caused by E. histolytica: Use Metrothabi alone or preferably in combination with iodoquinol or diloxanide furoate. The usual dose for adults is 750mg, used 3 times a day for 5 to 10 days. With amoebic liver abscess: Adults use a dose of 500-750 mg, 3 times a day for 5 - 10 days. Children use at a dose of 35-40 mg/kg/24 hours, divided into 3 doses/day for 5 - 10 days. With Giardia disease: Adults use with a dose of 250mg, orally 3 times a day for 5-7 days or use once a day 2g/day for 3 days. Children reduce the dose to only 15 mg/kg/day, divided into 3 times, taking the drug for 5-10 days. Treatment of anaerobic bacterial infections: Oral: Use the drug at a dose of 7.5 mg (base)/kg, up to a maximum of 1g, every 6 hours, once every 6 hours, orally for 7 days or longer. Antibiotic-associated colitis: Use the drug with a dose of 500mg (base) for a period of 3-4 times per day. Peptic ulcer disease caused by H pylori: 500 mg (base) 3 times daily. Patients should be combined with bismuth subsalicylate or colloidal bismuth subcitrate and some antibiotics such as penicillin or amoxicillin for 1-2 weeks.
4. Metrothabi drug side effects
During the use of the drug, patients may experience some side effects such as nausea, diarrhea, abdominal pain, allergies, rash. In some cases, there may be leukopenia, anorexia, agranulocytosis...
During the use of Metrothabi, if the patient encounters unusual problems, please contact your doctor. for the best advice.
5. Metrothabi drug interactions
Metrothabi has the ability to increase the effect of oral anticoagulants, especially warfarin, so patients should avoid taking it at the same time. Do not use with disulfiram because it can cause neurotoxicity such as psychosis, confusion. Concomitant use with phenobarbital increases the metabolism of metronidazole in the drug, so it will reduce the effect of Metrothabi. Metrothabi may affect vecuronium which is a non-depolarizing muscle relaxant. To avoid drug interactions, the patient should inform the doctor about other drugs currently taking, including Western medicine, Eastern medicine or functional food. From here, the doctor will prescribe the appropriate medication.
6. Precautions while using Metrothabi
Because Metrothabi inhibits alcohol dehydrogenase and alcohol oxidizing enzymes, it is easy to cause hot flushes, headaches, nausea, vomiting, abdominal cramps and sweating when used. Metrothabi may produce a false-positive response to the Nelson test. Using the drug in high doses in the treatment of anaerobic infections and the treatment of amoeba and Giardia can cause blood organ disorders as well as some other neurological diseases. Above is some information about the drug Metrothabi. You can refer to the use of drugs in the right circumstances to help bring the most effective treatment.Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
