This is an automatically translated article.
Tesrax belongs to the group of antiparasitic, anti-infective, antiviral and antifungal drugs with the main ingredient being Tenofovir disoproxil fumarate. The following is information about Tesrax's uses, dosage and precautions when using Tesrax.1. What is Tesrax?
What is Tesrax? Tesrax drug has the main ingredient is Tenofovir disoproxil fumarate 300mg, is prepared in the form of tablets and packed in boxes of 4 blisters x 7 tablets.
Tesrax is indicated for use in the following cases:
Treatment of HIV infection type 1; Treatment of chronic hepatitis B in adults.
2. Dosage and how to use Tesrax
2.1. Dosage For adults:
Treatment of HIV infection: Take 1 tablet x 1 time/day in combination with other antiretroviral drugs; Use in the prevention of HIV infection after occupational exposure (preferably within a few hours and continue for the next 4 weeks if tolerated): Take 1 tablet x 1 time/day in combination with antiretroviral other such as lamivudine or emtricitabine; Use in the prevention of HIV infection without occupational causes (most suitable within 72 hours and continue for 28 days): Take 1 tablet x 1 time / day in combination with at least 2 other antiretroviral drugs; Treatment of chronic hepatitis B: Take 1 tablet x 1 time / day for more than 48 weeks; For special cases: Dosage should be adjusted accordingly in patients with renal impairment: With creatinine clearance greater than 50 ml/min, use the usual once-daily dosing, creatinine clearance. 30 - 49 ml/min should be administered every 48 hours, creatinine clearance 10 - 29 ml/min should be administered every 72 - 96 hours; For patients on hemodialysis: Use 7 days apart or 12 hours after dialysis; For patients with impaired liver function, no dose adjustment is necessary. 2.2. How to use Tesrax is in the form of tablets that should be taken orally.
2.3. Management of missed dose Patients should take the dose as soon as they remember. If the missed dose is detected by the time it is almost time for the next dose, skip the missed dose. Avoid taking a double dose than prescribed.
Tesrax is indicated for use in adults for the treatment and prevention of HIV infection. When using the drug is used in combination with other antiviral drugs. The effect of Tesrax drug also helps to reduce the symptoms of hepatitis B effectively, thereby helping to relieve psychological pressure for patients.
2.4. Treatment of Overdose No symptoms have been reported in patients with overdose. In case of overdose, the patient should be closely monitored for signs of toxicity, and if necessary, the patient should be given basic supportive treatment measures. Studies have shown that Tenofovir is effectively eliminated by hemodialysis with a separation coefficient of approximately 54%. With a single 300 mg dose, approximately 10% of a tenofovir dose is eliminated during a 4-hour hemodialysis session.
In case of overdose and bad health signs occur, the best way is for relatives to take the patient to the nearest medical facility for timely support.
3. Notes when using the drug Tesrax
During the use of Tesrax, patients should note the following:
3.1. Contraindications Do not use Tesrax for people with a history of allergy to any of the ingredients in the drug.
3.2.Side effects Side effects that may occur during the use of Tesrax are as follows:
Common effects: Diarrhea, vomiting and nausea, abdominal pain, flatulence, indigestion, loss of appetite; Laboratory tests may show elevated serum amylase levels and pancreatitis during drug use; Hypophosphatemia has also been reported in some cases; Patients have reported skin rashes while using the drug. 3.3. Precautions Tesrax should be used with caution in the following cases:
When tenofovir was co-administered with lamivudine and efavirenz in patients with cough, a decrease in lumbar spine mineral density and an increase in plasma concentrations was observed. Levels of 4 biochemical factors in bone metabolism, increase in serum parathyroid hormone levels. In HIV-infected patients with a history of fractures, close bone monitoring is required, or at risk for osteoporosis. Although the effectiveness of calcium and vitamin D supplements has not been conclusively proven, supplementation may be beneficial for these patients. During the course of taking the drug, if there are bone abnormalities, the patient should consult a doctor immediately. There is no information on the use of tenofovir disoproxil fumarate during pregnancy, however, tenofovir disoproxil fumarate should be used only when the potential benefit and risk to the fetus have been weighed. In addition, the use of tenofovir disoproxil fumarate in women of reproductive age should be accompanied by contraceptive measures. There are no specific studies on the excretion of tenofovir disoproxil fumarate in human milk. Therefore, tenofovir should be avoided in nursing women. According to medical recommendations, women with HIV should not breastfeed to avoid transmitting HIV to their babies. There are no specific reports on the effects of this product on the ability to drive and use machines. However, to ensure the safety of this group of subjects, it is necessary to consult a doctor or pharmacist before use. 3.4, Drug interactions Tenofovir interacts with drugs such as acyclovir, cidofovir, ganciclovir, valacyclovir, valganciclovir, reducing renal function or competing for renal tubular secretion, increasing plasma concentrations of tenofovir or other drugs. Tesrax belongs to the group of antiparasitic, anti-infective, antiviral and antifungal drugs with the main ingredient being Tenofovir disoproxil fumarate. The drug is indicated for the treatment of hepatitis B and HIV. To ensure effective use, patients need to carefully read the instructions and consult the doctor, pharmacist for advice.
Follow Vinmec International General Hospital website to get more health, nutrition and beauty information to protect the health of yourself and your loved ones in your family.
