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Tenopaze drug is made in the form of eye drops, with the main ingredients being Ofloxacin and Dexamethasone phosphate. It is used in the treatment of inflammatory conditions in the eyes and ears.
1. What is Tenopaze?
1 Tenopaze 5ml vial contains 15mg Ofloxacin and 5mg/5ml Dexamethasone phosphate. In particular, Ofloxacin is an antibiotic of the fluoroquinolone group, with a broad spectrum of antibacterial activity including Enterobacteriaceae, Pseudomonas aeruginosa, Staphylococcus, Haemophilus influenzae, Neisseria spp., Streptococcus pneumoniae and a few other gram-positive bacteria strains. Ofloxacin is more active than ciprofloxacin against strains of Ureaplasma urealyticum, Chlamydia trachomatis, Mycoplasma pneumoniae. In addition, it is also active against Mycobacterium leprae and also Mycobacterium spp. other. Ofloxacin's ability to kill bacteria comes from the mechanism of inhibiting DNA-gyrase (an enzyme necessary in the process of replication, transcription, and repair of bacterial DNA).
And Dexamethasone is a type of fluomethylprednisolone, a synthetic glucocorticoid. Dexamethasone's mechanism of action is to bind to receptors in the cell, translocate into the cell nucleus, where it affects a number of genes to be translated. Dexamethasone has the main effects of anti-allergic, anti-inflammatory, immunosuppressive. In addition, it also has an electrolyte balance effect (very little).
Indications for using Tenopaze:
Treatment of blepharitis, conjunctivitis, lacrimal sac, stye, blepharitis, corneal ulcer, keratitis; Treatment of ear infections; Treatment of symptoms of infection after eye surgery. Contraindications to the use of Tenopaze:
Patients with allergies, hypersensitivity to the ingredients and excipients of the drug; Patients with a history of hypersensitivity and tendonitis caused by quinolones.
2. Usage and dosage of Tenopaze
How to use: Drop into eyes or ears.
Dosage:
Treatment of eye and ear inflammation: Eye or ear drops 1 drop/time x 3 times/day; Prophylaxis of infections after eye surgery: Instill 5 times a day for 2 days before surgery. A few days of surgery, eye drops depending on the time and type of surgery. It is recommended to instill 1 drop immediately after surgery, then eye drops each time the hand is bandaged.
3. Some notes when using Tenopaze
When using Tenopaze, users should note the following issues:
Tenopaze may cause some side effects such as: eyelid itching, blepharitis, eyelid swelling, eye pain, conjunctival congestion , red eyelids,... In addition, the patient may be shocked, hypersensitivity reactions (rare). It is best for the patient to inform the doctor about the side effects that he or she encounters when using the drug for advice on the most appropriate treatment; Use caution when using Tenopaze in children, pregnant and lactating women. Before using this drug in this group of people, it is necessary to consult a doctor. When using Tenopaze, patients should strictly follow the doctor's instructions on how to use and the dose of the drug. At the same time, patients should inform their doctors about the medicines they are taking so that they can be adjusted accordingly, avoiding the risk of drug interactions.
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