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Macromax drug with the main ingredient is Azithromycin 250mg in the form of Azithromycin dihydrate, which is indicated for the treatment of bacterial infections such as: pneumonia, ear infections, respiratory infections, skin infections,... infectious diseases. sexually transmitted bacteria. Below are some useful information about Macromax medicine to help patients learn and use the drug effectively and safely.
1. What is Macromax?
Macromax is a drug belonging to the group of drugs used to treat parasites, anti-infectives, antivirals, and antifungals. Macromax is manufactured in the form of hard capsules and is packaged in a box of 1 blister x 6 tablets.Macromax medicine has the main ingredient Azithromycin 250mg and some other excipients such as: Talc powder, Nath starch glyconate, Magnesium stearate, purified water, Polyvinylpyrolidon (PVP), Lactose, wheat starch, Nath laurylsulfate just enough 1 hard capsule.
2. What are the uses of Macromax?
What are the uses of Macromax? Macromax 250 is indicated for the treatment of patients in the following cases:Treatment of patients with infections caused by susceptible bacteria such as lower respiratory tract infections including: bronchitis, pneumonia. Treatment of skin and soft tissue infections, otitis media. Upper respiratory tract infections such as sinusitis, pharyngitis and tonsillitis. Macromax is indicated for use in patients who are allergic to penicillin, because of the risk of drug resistance. Azithromycin is indicated for the treatment of sexually transmitted infections in both men and women such as: Treatment of uncomplicated genital infections caused by Chlamydia trachomatis. Treatment of uncomplicated genital tract infections caused by non-multiresistant Neisseria gonorrhoeae (after ruling out concomitant Treponema pallidum infections). Macromax is used for the prophylaxis of Mycobacterium avium - intracellulare (MAC) infections in HIV-infected patients, alone or in combination with rifabutin. Macromax is indicated for the treatment of people with conjunctivitis caused by Chlamydia trachomatis or trachoma.
3. Dosage and how to use Macromax
3.1. How to use the drug Macromax is made in the form of hard capsules, which are tolerated in the body by mouth, according to tablets. The patient takes the tablet whole with a glass of purified water or cooled boiled water. Patients can take the drug 1 hour before or 2 hours after eating. 3.2. Dosage The dose of Macromax drug depends on each subject and the progress of each disease, the appropriate dose of Macromax drug will be used. Below is the dosage of Macromax 250 that patients can refer to as follows:
For adults:
Treatment of pharyngitis and tonsillitis caused by Streptococcus pyogens: In the first day of using the drug at a single dose of 500mg Macromax/day, then from day 2 to day 5, use the drug at a dose of 250mg Macromax/day, once a day. During the treatment of this disease, the total dose of the drug is 1.5g Macromax. Treatment of acute sinusitis caused by H.influenzae, M.catarrhalis or S.pneumoniae: The dose is 500mg Macromax/day, taken once a day, using the drug for 3 days. Treatment of acute superinfection in chronic obstructive pulmonary disease (COPD) caused by H.influenzae, M.catarrhalis or S.pneumoniae: In the first day use the drug at a single dose of 500mg Macromax/day, then from the 2nd day to the 5th day use the drug at a dose of 250mg Macromax / day, once a day. During the treatment of this disease, the total dose of the drug is 1.5g Macromax. Treatment of mild to moderate community-acquired pneumonia caused by susceptible strains of S.pneumoniae, H.influenzae, Mycoplasma pneumoniae or Chlamydophila pneumoniae: In the first day, use the drug at a single dose of 500mg Macromax/day, then from Day 2 to day 5 use the drug at a dose of 250mg Macromax / day, once a day. During the treatment of this disease, the total dose is 1.5g Macromax. Uncomplicated skin and skin structure infections caused by susceptible bacteria Staphylococcus aureus, S.pyrogens or S.agalactiae: On the first day of drug use at a single dose of 500mg Macromax/day, then from day 1 2nd to 5th day use the drug at a dose of 250mg Macromax / day, once a day. During the treatment of this disease, the total dose of the drug is 1.5g Macromax. Treatment of hyponatremia (genital ulcer caused by Haemophilus ducreyi): Use the drug at a single dose of 1g Macromax. Treatment of urinary tract infections and cervicitis caused by Neisseria gonorrhoeae or Chlamydia trachomatis: Use the drug at a single dose of 1g Macromax. Treatment of MAC (Mycobacterium avium) infection in HIV-infected patients: Primary prevention: Dosage is 1.2g Macromax, taken once a week. It can be used alone or in combination with Rifabutin 300mg/day. Treatment of disseminated MAC infection: The dose is 600mg/day, taken once a day, combined with Ethambutol 15mg/kg/day. Prevention of recurrence of disseminated MAC infection: The dose is 500mg/day, taken once a day, combined with Ethambutol 15mg/kg/day with or without rifabutin 300mg x 1 time/day. . Treatment of MAC (Mycobacterium avium) infection in HIV-negative patients (lung infection): The dose is 250mg/day or 500mg of Macromax/week, divided into 3 times a week. Oral combination with Rifabutin 300mg/day or rifambin 600mg/day and Ethambutol 25mg/kg/day for 2 months, then 15mg/kg/day. For children:
Using Macromax on the first day is 10mg Macromax/kg. Next, from the 2nd to the 5th day, the dose is 5mg Macromax/kg per day, once a day.
4. Contraindications of the drug Macromax
Macromax medicine is not used for patients with hypersensitivity or history of allergy to Azithromycin, Erythromycin or any Macrolide antibiotic, or to any of the ingredients.
5. Macromax drug side effects
During the use of Macromax 250, patients may experience some unwanted side effects as follows:
Common:
Digestive disorders such as: Nausea, abdominal discomfort, abdominal pain , abdominal cramps, vomiting, flatulence, diarrhea. Uncommon:
Fatigue, headache, dizziness, somnolence. Flatulence, indigestion, loss of appetite, and loose stools. Rash, itching. Rare:
Vaginitis , cervix. Anaphylactic reaction. Angioedema. Reversible hearing loss. A transient increase in liver enzymes. Sudden change in neutrophil count. When a patient encounters any unwanted side effects, they should immediately notify the doctor or pharmacist to take timely measures to avoid causing adverse health effects.
6. Pay attention to precautions when using the drug Macromax
Serious hypersensitivity reactions, including angioedema, anaphylaxis, skin reactions, have been reported rarely in patients receiving Azithromycin. It should be noted that Macromax is used in patients with impaired liver function, because the drug component Azithromycin is eliminated mainly through the liver. Although there are limited data on the use of Azithromycin in patients with renal impairment, Macromax should be used with caution in patients with a glomerular filtration rate less than 10 ml/min. There have been rare reports with Macrolid of prolongation of cardiac repolarization time and QT interval with increased risk of arrhythmias and torsades de pointes. Therefore, the possibility of the above effects of Azithromycin cannot be completely excluded in patients at risk of prolonged cardiac repolarization. Macromax should be used by patients only for the treatment and prevention of confirmed or suspected infections caused by susceptible organisms. To limit the development of drug-resistant bacteria, maintain the effectiveness of Azithromycin and other antibacterial agents during treatment. Macromax should not be used by pregnant women, only used when absolutely necessary and under the guidance of a doctor, pharmacist. Because, there are no adequate and well-controlled studies on the use of azithromycin in pregnant women. Macromax should be used with caution in lactating women, as Azithromycin is found in breast milk There is no evidence that Azithromycin has an effect on the ability to drive. or operate machinery while taking medication. Note: Macromax is prescribed by a doctor, patients absolutely do not use it on their own without a prescription for using Macromax.
Macromax drug with the main ingredient is Azithromycin 250mg in the form of Azithromycin dihydrate, which is indicated for the treatment of bacterial infections such as: pneumonia, ear infections, respiratory infections, skin infections,... infectious diseases. sexually transmitted bacteria. To ensure the effectiveness of treatment and avoid unwanted side effects, patients need to strictly follow the instructions of the doctor, professional pharmacist.
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