Uses of Telma 20

This is an automatically translated article.

1. What is Telma 20?

Telma 20 is manufactured by Glenmark Pharm., Ltd - INDIA and circulated on the market with registration number VN-4464-07. Telma 20 is a prescription drug that belongs to the category of angiotensin II receptor antagonists. Telma medicine contains the active ingredient Telmisartan.
Dosage form: film-coated tablets, each containing 20mg of Telmisartan and other excipients of the manufacturer. Package form: blister of 10 tablets, each box includes 1 blister and drug instruction sheet.

2. Uses of Telma

Telmisartan is an angiotensin II antagonist with strong affinity at the binding site for the AT1 receptor and no affinity for other receptors such as AT2, ... Telmisartan has the effect of reducing aldosterone levels in the blood. Telmisartan does not inhibit plasma renin and does not block ion channels, does not inhibit angiotensin converting enzyme, so there are no side effects caused by bradykinin. When a dose of 80 mg Telmisartan effectively inhibits angiotensin II's ability to raise blood pressure, this effect can be maintained for 24 to 48 hours. After taking the first dose of Telmisartan, the blood pressure-lowering effect gradually increased and markedly within 3 hours, reached a maximum after 4 weeks of treatment and maintained throughout the long-term treatment.
Telmisartan has the ability to reduce systolic and diastolic blood pressure without affecting heart rate.
If Telmisartan is discontinued, blood pressure will gradually return to pre-treatment values ​​within a few days without rebound hypertension.

3. Indications and contraindications for Telma 20

Telma 20 is usually indicated in the following cases:
Treatment of essential hypertension Prevent cardiovascular diseases Reduce cardiovascular disease in adults with the following factors: presence of atherosclerosis ( history of coronary heart disease, stroke, peripheral artery disease ) Type 2 diabetes with target organ damage Contraindications: absolutely do not use Telma drug in the following cases:
Hypersensitivity to any ingredient any of Telma Second and third trimester pregnant Women with biliary obstruction Severe liver failure In addition, the use of Telma with aliskiren-containing preparations is contraindicated in patients with diabetes or renal failure with GFR < 60ml/min/1.73 m2.

4. Dosage and how to use Telma

Telma 20 is a prescription drug, so patients can only use it when prescribed by a doctor and must follow the treatment schedule.
Dosage:
Adults
Treatment of essential hypertension: 40mg / time / day, some patients are effective with a dose of 20mg. If target blood pressure is not achieved, the dose can be increased to 80 mg once daily, keeping in mind that the maximum antihypertensive effect is achieved after 4 to 8 weeks of dosing. Prevention of cardiovascular diseases: the recommended dose is 80mg/time/day. For patients with renal impairment: There is limited experience with the treatment of Telma 20 in patients with severe renal impairment or on hemodialysis. A starting dose of less than 20 mg once daily is recommended in these patients.
For patients with hepatic impairment: mild to moderate hepatic impairment: the dose should not exceed 40mg/time/day. Telma is contraindicated in patients with severe hepatic impairment.
No dose adjustment of Telma 20 is required in the elderly.
Usage: Telma is prepared in the form of film-coated tablets and taken orally, take the drug with a sufficient amount of water, do not break, chew or crush the tablet, can take the drug independently with meals. Because Telma has hygroscopic properties, it should be stored in blister packs and used immediately after removing from the blister.
How to deal with forgetting a dose of Telma?
When you miss a dose, you can take another dose instead. If it is almost time for your next dose, skip the missed dose, skip the missed dose, or double it. How to deal with an overdose of Telma?
Very little is known about overdosage in humans, symptoms of Telma 20 overdose are prominently low blood pressure, increased heart rate, decreased heart rate, dizziness, increased serum creatinine, acute renal failure. When there is an overdose, it is necessary to quickly bring the patient to the nearest hospital for emergency treatment. Family members should bring medical records and all previous medications the patient has taken to support the diagnosis. Patients should be closely monitored and treated symptomatically and supportively. Telma 20 is not removed from the body by hemodialysis. Treatment including induction of vomiting, gastric lavage, and administration of activated charcoal may be helpful. If the patient is hypotensive, the patient should be placed in the supine position and given rapid saline infusion. Regular monitoring of electrolytes and creatinine levels.

5. Undesirable effects of the drug Telma

In addition to the therapeutic effect, Telma drug may cause some unwanted effects during use such as:
Uncommon: cystitis, pharyngitis, sinusitis, anemia, hyperkalemia, loss sleep, depression, unconsciousness, dizziness, bradycardia, hypotension, orthostatic hypotension, cough, dyspnea, diarrhea, abdominal pain, flatulence, dyspepsia, vomiting, back pain, convulsions myalgia, myalgia, acute renal failure, chest pain, asthenia, hypercreatinine, ... Rare, very rare: sepsis, thrombocytopenia, eosinophilia, anaphylactic reaction, too Hypersensitivity, hypoglycemia in patients with diabetes, anxiety, somnolence, visual disturbances, bradycardia, interstitial lung disease, dry mouth, taste disturbances, gastric discomfort, liver dysfunction, arthralgia, extremity pain, tendon pain, flu-like symptoms, angioedema, discoid eczema, erythema, urticaria, rash, hyperuricemia, elevated liver enzymes, increased blood creatine phosphokinase, decreased hemoglobin, .. These are not all side effects of Telma 20, patients may experience some Other side effects have not been reported or studied. Therefore, contact your doctor as soon as you have any unusual symptoms while using Telma.

6. Drug interactions

Treatment with many drugs can cause interactions between the components in the drug, affecting the bioavailability, effects, and toxicity of the drug. In addition, some diseases such as immunodeficiency, liver failure, kidney failure, ... can also affect the effectiveness of the drug.
Therefore, in order to use Telma drugs safely and effectively, patients need to list and inform their doctors about all medications they are taking as well as their current health status. At the same time, it is necessary to discuss with your doctor the use of certain foods and beverages such as alcohol, stimulants, and fermented foods during treatment with Telma.
Drugs that can interact with Telma 20 such as:
Digoxin: when used with Telmisartan, it will increase the concentration of Digoxin in the blood. Immunosuppressants (cyclosporin, tacrolimus), other renin-angiotensin-aldosterone system-acting drugs, potassium-containing salts, potassium-sparing diuretics, heparin, NSAIDs, trimethoprim: when combined with telma, the risk increases. hyperkalemia. Lithium: when used together with Telmisartan will increase the concentration of Lithium in the blood. Non-steroidal anti-inflammatory drugs (NSAIDs) may reduce the antihypertensive effect of Telma 20 and lead to impaired renal function. Diuretics (thiazides or loop diuretics): may lead to fluid loss and risk of hypotension when combined with Telma 20. Other antihypertensive agents: may increase the antihypertensive effect of telmisartan when used at the same time. Systemic corticosteroids: Decreased antihypertensive effect when used concomitantly with telmisartan.

7. Some notes when using Telma

Use Telma 20 during pregnancy: Telma should not be used in the first trimester of pregnancy, contraindicated in the second and third trimesters.
Use of Telma 20 during lactation: There is not enough evidence on the safety of using Telma during breast-feeding. Therefore, it should not be used, especially when feeding infants or premature infants.
Caution should be taken when administering Telma to patients in the following cases: hypertension due to renal artery stenosis, impaired renal function, volume depletion or sodium depletion due to strong diuretics, diarrhea, vomiting vomiting; primary hyperaldosteronism syndrome, aortic stenosis, mitral stenosis, obstructive hypertrophic cardiomyopathy, diabetes.

8. Preservation of drugs

Store Telma medicine in the original manufacturer's packaging, in a cool, clean place, avoid direct exposure to sunlight, temperature below 30 degrees Celsius. Keep Telma 20 out of reach of children as well as children. pets, avoid them not knowing how to chew can cause serious unwanted effects. Do not use Telma medicine that has expired or shows signs of change in color, properties, taste, no labels. Do not throw Telma 20 into the toilet or plumbing unless told to do so. Telma drug contains the main ingredient Telmisartan, commonly used in the treatment of essential hypertension. To ensure the effectiveness of treatment and avoid unwanted side effects, patients need to strictly follow the instructions of the doctor, professional pharmacist.
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