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Tadaritin is a drug with the main active ingredient belonging to the group of antiallergic drugs, often used in cases of hypersensitivity. Currently, the drug is used to treat symptoms in cases of diseases such as rhinitis, urticaria.1. What is Tadaritin?
Tadaritin has the active ingredient Desloratadin 5mg and a system of excipients including: Anhydrous disodium phosphate, corn starch, microcrystalline cellulose, lactose monohydrate, modified corn starch, anhydrous silicon dioxide, cottonseed oil, magnesium stearate , Opadry AMB Blue 80 W30580...Desloratadine is the major orally active metabolite of loratadine, which is an antihistamine without the side effects of drowsiness. Desloratadine antagonizes histamine with immediate and long-term effectiveness, selectively antagonizing peripheral histamine - H1 receptors, and does not penetrate the central nervous system.
Desloratadine has anti-allergic effects by inhibiting the release of inflammatory cytokines (IL-4, IL-6, IL-8, IL-13) from mast cells and basophils in the human body. inhibits the expression of the adhesion molecule P-selectin in endothelial cells.
Desloratadine works to relieve the symptoms of the disease such as: relieve sneezing, runny and itchy nose, congestion, nasal congestion, itchy eyes, watery eyes, red eyes, itchy palate. Desloratadine was able to effectively control these unpleasant symptoms for 24 hours. In addition, Desloratadine is effective in relieving symptoms of urticaria, reducing itching and reducing the size and number of rashes.
2. Uses of Tadaritin
Tadaritin 5mg tablets are indicated for adults and adolescents (> 12 years of age) for the relief of symptoms of the following conditions:
Seasonal allergic rhinitis or chronic rhinitis; Urticaria disease.
3. Dosage of Tadaritin
Tadaritin is to be taken orally as directed by the treating doctor.
Adults, children over 12 years old and the elderly: the usual dose of Tadaritin is 5mg desloratadine (1 Tadaritin tablet), used as a single daily dose; Children under 12 years of age: There are no research data to determine the safety of Tadaritin and its effects on children under 12 years old, so Tadaritin should not be used for children under 12 years old; Patients with impaired liver function and renal failure: The starting dose of Tadaritin is 5 mg, administered every other day or according to the pharmacokinetics of Tadaritin.
4. Contraindications of Tadaritin
Tadaritin has certain contraindications for some subjects to limit unwanted side effects. Specifically:
Hypersensitivity to the main active substance or any of the ingredients of Tadaritin; Hypersensitivity to loratadine; Children under 12 years old.
5. Notes when using Tadaritin
The efficacy and safety of Desloratadine in children under 12 years of age has not been specifically studied; Tadaritin should be used with caution in patients with severe renal impairment; Patients with hereditary problems of galactose absorption, lactase deficiency or galactose malabsorption should not take Tadaritin.
6. Undesirable effects of the drug Tadaritin
The most common side effects of Tadaritin:
Fatigue; Dry mouth ; Headache. Some of the rare but reported adverse effects that have been reported in the post-marketing experience of Tadaritin may be listed below:
Mental confusion, hallucinations, dizziness; Drowsiness, insomnia, increased brain activity; Convulsions; Heart disorders, palpitations, tachycardia; Intestinal disorders: abdominal pain, nausea, vomiting, dyspepsia, diarrhea; Liver dysfunction, elevated liver enzymes, increased bilirubin or hepatitis; Bone and connective tissue disorders; Myalgia, General disorders; Hypersensitivity reactions: anaphylaxis, edema, dyspnoea, pruritus, rash...
7. Tadaritin drug interactions
No clinically significant interactions have been observed with the concomitant use of Desloratadine active tablets with erythromycin or ketoconazole. Desloratadine when taken with alcohol does not reduce the risk of side effects from alcohol.
8. Can Tadaritin be used during pregnancy and lactation?
Desloratadine contained in Tadaritin did not affect embryonic development in animal studies. However, the safety of use of Tadaritin during pregnancy has not been established, so desloratadine is not recommended during pregnancy. Breastfeeding women should not use Tadaritin because desloratadine is excreted in breast milk.Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
