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Somargen is indicated in the treatment of severe acute gastrointestinal bleeding, prevention of postoperative complications after pancreatic surgery, treatment of pancreatic fistula, acute pancreatitis,... Let's learn about Uses, notes when using Somargen through the article below.1. Uses of the drug Somargen
Somargen medicine contains the active ingredient Somatostatin 3mg, prepared in the form of lyophilized powder for injection.Somatostatin, isolated from the hypothalamus or synthetically, is a polypeptide consisting of 14 amino acids. Somatostatin inhibits the release of growth hormone from the anterior pituitary gland, inhibits the release of thyrotrophin and pituitary corticosteroids, insulin and glucagon from the pancreas, and regulates the secretion of gastric juice. On the central nervous system, somatostatin plays an important role in pain perception.
Somargen drug is indicated in the treatment of severe acute gastrointestinal bleeding, prevention of postoperative complications after pancreatic surgery, treatment of pancreatic fistula, acute pancreatitis,...
2. Dosage of the drug Somargen
Somargen is used to treat and prevent acute bleeding by intravenous route. The specific dose of the drug is prescribed by the treating doctor based on the medical condition. Patients should absolutely not self-medicate without a doctor's prescription.Some recommendations on the dosage of Somargen are as follows:
Treatment of acute upper gastrointestinal bleeding: Continuous intravenous infusion of 3.5 μg/kg/hour in sterile and nonpyrogenic physiological diluent for injection. In some cases, before a slow intravenous infusion lasting more than 3 minutes 250μg Somargen should check the patient's arterial blood pressure; The duration of treatment with Somargen should be extended to 48 - 72 hours and not more than 120 hours after it is certain that bleeding has stopped; Prevention of postoperative complications: Using Somatostatin at the same time as surgery and prophylactic treatment in patients for 5 days after surgery; Treatment of acute pancreatitis, pancreatic fistula: Intravenous infusion of 3.5μg/kg/hour for 7-10 days; Adjunctive therapy in diabetic patients with ketosis: Concomitant administration of Somargen and insulin by intravenous infusion of 100 - 500 3.5 μg/hour Somatostarin plus insulin (10 units intravenously, 1 to 4.8 units intravenous infusion). taste/hour) normalizes blood glucose levels in 4 hours and resolves ketoacidosis in 3 hours.
3. Side effects of the drug Somargen
Somargen medicine can cause some unwanted effects as follows:Common: Feeling tired, sick, dizzy, hot flushes, nausea,... These side effects usually occur when injections too quickly; Rare: Postural hypotension, respiratory depression, abdominal pain, diarrhea, vomiting, increased secretion of growth hormone and other hormones on discontinuation of the drug; Side effects of unspecified frequency: Arrhythmia, poor glucose tolerance, hyponatremia,... Patients need to inform their doctor about unwanted effects encountered while being treated with Somargen.
4. Notes when using Somargen
4.1. Contraindications
The use of Somargen is contraindicated in the following cases:Patients are allergic to Somatostatin or any of its ingredients; Pregnant women; Women are breastfeeding.
4.2. Use caution
Somargen should be used under medical supervision. Somargen has the effect of blocking insulin and glucagon secretion, so caution should be exercised when using the drug in insulin-dependent patients. For these patients, it is important to monitor the risk of temporary hypoglycemia, followed by the risk of hyperglycemia occurring after 2 to 3 hours. Therefore, it is important to check your blood sugar every 3-4 hours and do not take extra sugar. Overdose of Somargen drug appears symptoms such as vomiting, nausea, metabolic disorders, abdominal pain, ... In this case, the patient should stop using Somargen and notify the treating doctor. Store Somargen at room temperature, away from high humidity and direct sunlight.5. Drug interactions
Do not use Somargen concurrently with solutions containing fructose or glucose. Co-administration of Somargen with barbiturates prolongs the hypnotic effects of barbiturates and increases the convulsive effects of pentetrazole. Drug interactions occur that increase the risk of having an effect and reduce the therapeutic effect of Somargen, so to ensure safety and effectiveness in treating patients, it is necessary to inform the doctor about the drugs and foods that are being used. used before taking Somargen.Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
