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Somaritin drug has the main active ingredient Somatostatin in the form of Somatostatin acetate hydrate with the content of 3mg/tube. This is a drug that works in the treatment of gastrointestinal bleeding, acute pancreatitis and supports the treatment of diabetics with acid-ketonemia,...
1. What is Somaritin?
What is Somaritin? Somaritin medicine has the main active ingredient Somatostatin in the form of Somatostatin acetate hydrate with the content of 3mg/tube. This is a drug that works in the treatment of gastrointestinal bleeding, acute pancreatitis and supports the treatment of diabetics with ketoacidosis,...
Somaritin is prepared in the form of lyophilized powder mixed with water. injection and 1 ampoule of diluent for injection of 1 ml. This is an intravenous drug.
1.1. Pharmacokinetics of the active ingredient Somatostatin Active ingredient Somatostatin is a 14-aminoacid oligopeptide isolated from the hypothalamus of animals and subsequently found in epithelial cells and nerve fibers throughout the digestive system.
1.2. The effect of the active ingredient Somatostatin Active ingredient Somatostatin is a growth hormone that helps reduce bleeding in the stomach, duodenum and esophagus. The active ingredient Somatostatin is considered to have a major role as a local transporter, thereby having a function in regulating the secretion of hormones and hormones, and at the same time controlling the activity of gastrointestinal motility. chemical. When used at therapeutic doses with pharmacological effects, the active ingredient Somatostatin is effective in inhibiting gastrointestinal function and motility. It is then broken down in the body's gastrointestinal system.
2. What disease is Somaritin used to treat?
Somaritin is indicated for use in the following specific cases:
Treatment of severe acute bleeding in the upper gastrointestinal tract (bleeding caused by gastric ulcer, duodenal ulcer and gastroduodenal, bleeding gastritis or esophageal bulge). Prophylactic treatment of complications after pancreatic surgery. Treatment of pancreatic fistula and acute pancreatitis. Adjunctive treatment for diabetics with acid-ketosis.
3. Usage and dosage of Somaritin
After knowing the active ingredients of the drug, the patient needs to find out information about how to use and dose the drug to be most effective.
3.1. How to use the drug Somaritin Somaritin is used as an intravenous infusion.
Patients need to strictly follow the instructions of doctors and medical staff to ensure effectiveness and avoid unwanted side effects that may occur.
3.2. Subjects using the drug Somaritin Somaritin can be used for adults and children.
3.3. Dosage of the drug Somaritin Initial therapeutic dose: about 3.5 mcg/kg, eg 1 ampoule 250 mcg for a 75 kg person, diluted immediately before use with 1 ampoule of physiological saline solution and intravenously slowly not less than 1 minute. Thereafter, it should be continued by continuous intravenous infusion at a dose of 3.5 mcg/kg/hour, eg 1 ampoule of 3 mg administered for > 12 hours. Should be treated continuously from a minimum of 48 hours to a maximum of 120 hours (equivalent to 5 days of treatment). It should be noted: The above dosage is for reference only, because Somaritin is indicated by intravenous infusion, so patients should strictly follow the indications and instructions. Administer the infusion only under the supervision of a doctor and medical staff.
4. Undesirable effects of the drug Somaritin
During the use of Somaritin, patients may experience some unwanted side effects as follows:
During the use of Somaritin, it may cause a feeling of fatigue, weakness, occasional vomiting, dizziness. face, hot face. This occurs when the drug is injected intravenously in too short a time, not with continuous infusion. Rare adverse effects of Somaritin in cases of orthostatic hypotension, evident when administered in supine patients. Respiratory depression may occur with intravenous infusion of drugs containing the active ingredient somatostatin in high doses. In addition, other undesirable effects may include vomiting, diarrhea, abdominal pain, increased secretion of growth hormone and other hormones when the drug is stopped and infrequently, less glucose tolerance, cardiac arrhythmias. , reducing sodium in the blood.
5. Some notes when using Somaritin
During the use of Somaritin, patients need to pay attention to some of the following:
5.1. Contraindications of the drug Somaritin Somaritin drug is contraindicated for the following people:
People with sensitive or hypersensitivity to the components of the drug and other related chemicals. Women who are in pregnancy, childbearing, and breastfeeding. 5.2. Warnings and cautions when using Somaritin The use of Somaritin requires close examination of the doctor treating the disease. Because of its inhibitory effect on insulin and glucagon secretion, Somaritin must be used with caution when treating bleeding in insulin dependent patients. In these subjects, transient hypoglycemia should be observed, followed by a rise in blood glucose that occurs after a period of 2 to 3 hours. Therefore, it is necessary to check blood sugar every 3-4 hours and avoid using extra sugar. 5.3. Storage conditions Somaritin medicine Store Somaritin in a dry place, the temperature does not exceed 30°C, avoid direct sunlight. After reconstitution, the Somatostatin solution can be stored in the refrigerator (5°C – 3°C) for no more than 24 hours. Shelf life: The shelf life of the drug stated in the packaging is 36 months from the date of manufacture. Above is all information about the drug Somaritin, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Absolutely do not arbitrarily buy Somaritin to treat the disease at home, because there may be unwanted side effects on health.
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