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The drug Soluboston is used to treat - reduce inflammation, and allergies, the main ingredient is Prednisolone. Let's find out more details about the uses, usage and notes when using Soluboston through the following article.
1. What is Soluboston?
Soluboston drug belongs to the group of Hormonal and Hormonal drugs. The drug has the main ingredient Prednisolone (in the form of Prednisolone sodium metasulfobenzoate 20mg), which is used in the treatment or reduction of inflammation and allergies.
Soluboston is prepared in the form of effervescent tablets, packaged in a box of 2 blisters of 5 blisters, 10 blisters x 10 tablets or a box of 1 bottle of 20 tablets.
2. What are the uses of Soluboston?
Soluboston is indicated to treat and relieve inflammation and allergies in the following specific cases:
Collagen - connective tissue:
Systemic lupus erythematosus; Inflammation of blood vessels; Polymyositis; Visceral sarcoidosis. Dermatology:
Severe autoimmune blistering of the skin: Pemphigus and Pemphigoid scalds; Severe Angiomas - subcutaneous hemangiomas; Flat lichen ; Acute urticaria; Severe neutropenia. Gastrointestinal:
Advanced stage ulcerative colitis; Crohn's disease; Chronic autoimmune hepatitis.; Severe alcoholic hepatitis. Endocrine:
de Quervain's subacute thyroiditis; Increased blood calcium. Hematology:
Severe immune thrombocytopenic purpura; Anemia ; Autoimmune red blood cell loss; Combination for the treatment of malignant lymphoma; Chronic or congenital thrombocytopenia. Infection:
Tuberculosis pericarditis; Severe TB status; Pneumocystis carinii pneumonia with severe hypoxia. Lung cancer:
Reducing nausea in chemotherapy for lung cancer. Reduce edema/inflammation during radiation and chemotherapy for cancer treatment. Kidneys:
Nephrotic syndrome ; Nephrotic syndrome due to local hyalinization and glomerular foci; Lupus stage III, IV; Sarcoid granuloma in the kidney; Vasculitis with renal failure; Vascular proliferative glomerulonephritis. Nervous:
Myasthenia gravis; Brain edema due to tumor; Polymyositis - chronic autonomic nerve; West syndrome; Lennox-Gastaut syndrome; When repeated intravenous corticosteroids cause multiple sclerosis. Eyes:
Anterior uveitis; Severe posterior uveitis; Eye swelling; Neurological diseases of the eye caused by intravenous corticosteroids. Ear, nose, throat:
Otitis media with exudate; Nasal polyps ; Acute or chronic sinusitis; Short-term treatment of seasonal allergic rhinitis; Acute laryngitis with stridor in young children. Respiratory:
Continuous asthma (in this case, short-term treatment is recommended, in case there is no improvement with high-dose inhaled therapy); Acute asthma, severe acute asthma; Chronic obstructive pulmonary disease; Development of Sarcoidosis; Diffuse interstitial lung fibrosis. Joints:
Rheumatoid arthritis ; Polyarthritis ; Rheumatoid muscle pain; Horton's disease ; Acute rheumatic fever; Severe brachial neuritis, neck; Organ transplantation and hematopoietic stem cells. Prophylaxis - transplant treatment:
Prophylaxis and treatment of host disease against transplantation.
3. Dosage and how to use Soluboston
3.1. How to take Soluboston is for oral administration. The patient uses the tablet to put it in a glass of water, wait for the effervescent tablet to dissolve in the water, and then drink it with breakfast. Patients must not arbitrarily stop taking the drug suddenly during prolonged treatment, must follow the recommendations of the doctor, pharmacist to reduce the dose of the drug. For the best effect, the patient must take the medication regularly. If you miss a dose, continue treatment as usual. The drug is used for acute or short-term treatment with medium or high doses in adults or children > 10 kg. Long-term maintenance dose lower than 20 mg/day. 3.2. Dosage Adults:
The specific dose depends on the diagnosis, prognosis, severity of the disease and the patient's ability to tolerate the drug. The lowest dose should be used for the short term to minimize unwanted effects.
Attack treatment: Dosage 0.35 - 1.2 mg Prednisolone/kg/day. In severe inflammatory cases: 0.75 1.2 mg Prednisolone/kg/day. For other special cases, a higher dose of Prednisolone may be required. Children:
Dosage depends on the severity of the disease and the weight of the child.
Children > 10kg: Attack treatment: 0.5-2 mg Prednisolone/kg/day. Alternate corticosteroid therapy is used in children to prevent rickets. Alternating therapy should be considered only if inflammation has been controlled with high doses of corticosteroids and there has been no recurrence during treatment. Children <10kg : Use of low-dose drugs is more appropriate. Patients should be treated with a loading dose until their condition is well controlled. In the case of prolonged use of Prednisolone, the dose reduction should be gradual without abrupt discontinuation, if necessary, the maintenance dose can be continued. Patients who are indicated for long-term use of high doses should take the first dose twice a day and then use a single daily dose in the morning.
In patients whose systemic corticosteroid dose is > physiological dose for more than 3 weeks of drug therapy, Prednisolone should not be stopped abruptly. The decision to discontinue the drug will depend mainly on the starting dose, the disease to be treated, and the duration of treatment.
Treatment with corticosteroids reduces the secretion of hormones such as ACTH and cortisol, prolonged use of Prednisolone may cause adrenal dysfunction. It is necessary to gradually discontinue the drug, with an average reduction of 10% over 8-15 days to ensure recovery of the HPA axis and prevent the risk of disease recurrence.
For treatment courses shorter than 10 days: It may not be necessary to gradually reduce the dose of Prednisolone.
4. Contraindications to taking Soluboston
Do not use Soluboston in the following cases:
Patients with hypersensitivity to Prednisolone or any active ingredient in the drug. The patient gets an infection in all cases. Developing viral infections such as: Hepatitis, shingles, herpes, chickenpox. Uncontrolled neurological disorder. Are taking live or attenuated vaccines.
5. Soluboston drug interactions
When using Soluboston in combination with some other drugs, there may be drug interactions such as:
Sultopride will affect the central nervous system. Live vaccines have reduced potency. To ensure safety and avoid possible interactions, please list the medications you are taking to your doctor or pharmacist for the most appropriate medication direction.
6. What side effects does Soluboston cause?
Soluboston is usually best tolerated when the patient strictly follows the medication instructions from the doctor or pharmacist. However, in the process of taking the drug, patients may experience some unwanted and unpleasant effects such as:
Round and red face, weight gain. Bruises appear. Arterial hypertension. Stimulate. Sleep disorders. Fragile bones, fractures, osteoporosis. Change the biological parameters of potassium, salt, sugar. Risk of adrenal insufficiency. Growth disorders in children. Menstrual cycle disorder. Tendon rupture. Muscle weakness. Gastrointestinal ulcers and digestive disorders. Skin disorders. Increased intraocular pressure. Cataracts. Inform the doctor or pharmacist of all adverse effects or body discomforts that the patient experiences, so that the most appropriate treatment can be given.
7. Precautions while using Soluboston
Before using Soluboston for treatment, patients should note some of the following notes:
Prednisolone must be used under close medical supervision. Inform the treating physician if the patient has recently been vaccinated, has peptic ulcer disease, colon disease, diabetes mellitus, recent bowel surgery, arterial hypertension, tuberculosis infection, liver failure , renal failure , osteoporosis and myasthenia gravis with muscle fatigue. If the patient has recently stayed in the tropics, southern Europe or subtropical regions, it is necessary to inform the treating doctor to avoid the risk of malaria. Avoid the combined use of Prednisolone with Sultopride, the live vaccine has reduced dynamics. When taking Prednisolone, avoid contact with people who have measles or chickenpox. In the case of prolonged prednisolone treatment, do not stop the drug suddenly without consulting your doctor or pharmacist. During treatment and after 1 year of stopping drug treatment, patients must inform their doctor about the use of corticosteroids when having surgical intervention or having fever or illness. Oral or injectable corticosteroids may facilitate liver disease, tendon rupture (exception), notify physician when tendon pain occurs. During treatment, the patient should follow a low-salt and low-salt diet. Soluboston should be used during pregnancy only if clearly needed. Patients should consult a doctor before taking the drug in case of pregnancy while taking the drug so that the doctor can consider and decide whether to take the drug or not. Prednisolone should not be used while breastfeeding because it is excreted in breast milk. Above is all information about Soluboston medicine, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Absolutely do not arbitrarily buy Soluboston treatment at home because there may be unwanted side effects.
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