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Sindazol drug is prepared in the form of an infusion solution, with the main ingredient being Tinidazol. The drug is used in the treatment of preventing infection after surgery. To learn more about this drug, refer to the information in the following article.
1. Uses of the drug Sindazol
Sindazol is prepared in the form of an infusion solution. Each 100ml contains Tinidazol 500mg and excipients. Tinidazol is a derivative of the imidazole group, which is effective against protozoa and anaerobic bacteria (through the mechanism of penetrating microbial cells, destroying DNA chains, inhibiting the whole process of DNA chain synthesis).
Indications for use of Sindazol: Prevention of anaerobic infections during and after surgery, especially surgery in the digestive system (typically the colon) and surgical surgeries. The drug is used to treat specific infections in the following cases:
Bacteremia, infections in the peritoneal system, infections of the skin and surrounding structures, infections of the upper and lower respiratory tract (pleurisy, inflammation of the lungs). respiratory tract, sinusitis ), inflammation of the genital tract (vaginitis),...; Ulcerative gingivitis, ulcers in the mouth; Other diseases: Intestinal amoeba, giardiasis, hepatic amoeba. Contraindications to use Sindazol drug:
People with hypersensitivity to the ingredients/excipients of the drug; Patients with neurological disorders; Pregnant women in the first 3 months of pregnancy, women who are breastfeeding; People with a history of blood dyscrasias.
2. Usage and dosage of Sindazol
How to use: Use intravenous line, by experienced medical staff.
Dosage: Should be used continuously for 1 week before or after surgery with the following dose:
Adults: 100ml intravenous infusion at the rate of 5ml/min. Infusions should be spaced 8 hours apart; Children from 5 to 12 years old: Use with the adult dose of 1/2. Missed dose: If a dose is missed, the patient should notify the medical staff to receive a full dose.
Overdose: There have been no reports of overdoses of Sindazol. In case of overdose, supportive measures such as gastric lavage should be used. Tinidazole in the drug is easily eliminated by dialysis. In case of overdose, the patient should go to the nearest hospital for timely monitoring and treatment.
3. Side effects of the drug Sindazol
Some side effects patients may encounter when using Sindazol include:
Common: Thrombophlebitis, loss of appetite, nausea, abdominal pain, pain at the injection site; Uncommon: Dizziness, headache, vomiting, diarrhea; Rare: Reversible leukopenia, fever, allergies, stomatitis, arthralgia, rash, rash, itchy skin, dark urine, peripheral neuropathy. When experiencing side effects of Sindazol, the patient should immediately notify the doctor for timely intervention.
4. Be careful when using Sindazol
Some notes patients need to remember before and while using Sindazol:
Stop taking Sindazol in case the patient has dizziness, loss of coordination, dark consciousness; People with severe central nervous system and peripheral neuropathy should consult a doctor before taking the drug. Pregnancy: Tinidazol (the main ingredient of Sindazol) can cross the placental barrier. However, there are no adequate studies on the effects of the drug on the development of the fetus, so it is best not to use the drug in the first 3 months of pregnancy. doctor's opinion); Lactation: Tinidazole is excreted in human milk for more than 72 hours after administration. Therefore, do not breastfeed for at least 3 days from the time the mother takes the drug; Patients should stay away from infectious agents while using Sindazol.
5. Sindazol drug interactions
When using Sindazol at the same time as alcohol, stimulants can cause disulfiram-like reactions. Therefore, alcohol and stimulants should be discontinued while taking Sindazol. To ensure safety, the patient should also inform the doctor about the drugs/health foods he is taking, his/her medical history to consider possible drug interactions. .
During the course of using Sindazol, the patient should absolutely follow all instructions of the doctor to ensure the best therapeutic effect, reduce the risk of unpredictable events.
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