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Risperidone belongs to the group of atypical antipsychotics. It is used to treat certain mental disorders such as schizophrenia, bipolar disorder, and autism spectrum disorder.
1. What is the effect of sernal?
Sernal 2mg has the main ingredient is Risperidone, belongs to the group of psychotropic drugs. Sernal 2mg drug is prescribed by doctors to be used in the following treatment cases:
Treatment of acute and chronic schizophrenia. Treatment of symptoms such as depression and anxiety associated with schizophrenia. Treatment of manic symptoms caused by bipolar disorder. Treatment of behavioral disorders in patients with dementia. Treatment of autism in children and adolescents. Mechanism of action:
Risperidone is an antipsychotic drug that works by changing the effects of chemicals in the brain. The main effect of Risperidone is to decrease Dopaminergic and Serotonergic activity in the brain. Thus reducing the symptoms of schizophrenia and mood disorders.
2. Dosage and usage
Usage : Sernal drug is taken orally, can be before or after meals.
Dosage:
Usual dose: Use 1mg 2 times a day, on the first day. The dose may then be increased by 1 mg daily until the total dose is 6-8 mg/day. In the treatment of schizophrenia in adults: Risperidone should be initiated at a dose of 2 mg/day. The dose may be increased to 4mg on subsequent days. This dose may be maintained or adjusted according to individual patient response. However, it is not recommended to use more than 16mg/day because the safety of the drug has not been evaluated. In the treatment of schizophrenia in the elderly: Use a starting dose of 0.5 mg x 2 times / day. This dose can be adjusted in increments of 0.5 mg to a maximum of 2 mg of risperidone per oral dose. In the treatment of bipolar disorder - manic in the elderly: The starting dose is 2mg/day. In case of need to increase the dose, it should be increased by 1mg/day. Treatment of behavioral disorders in dementia patients: The initial dose of the drug is 0.25mg x 2 times/day. In case of necessity, the patient can increase by 0.25mg x 2 times / day depending on the level of need. In the treatment of autism in children and adolescents: The dose of Risperidone must be prescribed specifically according to the individual patient's needs and response to therapy. Reference:
Children weighing less than 20 kg on 1-3 days use 0.25mg dose, from 4th to 14th day use 0.5mg dose. When the dose needs to be increased, it should be increased by 0.25 mg every 2 weeks. Children weighing more than 20kg on days 1-3 use a dose of 0.5mg, from days 4 to 14 use a dose of 01 mg. When a dose increase is required, it should be increased by 0.5 mg every 2 weeks. For patients with liver and kidney failure: The dose should be adjusted according to the doctor's prescription.
3. Side effects
Common side effects of Sernal drugs affecting the nervous system, muscle system, digestive system, vision, cardiovascular system include: Dizziness, increased excitability, anxiety, somnolence, extrapyramidal symptoms, headache. , blurred vision, back pain, chest pain, fever, fatigue, sexual dysfunction, constipation, abdominal pain, nausea, indigestion, loss of appetite, toothache; rhinitis, cough, sinusitis, pharyngitis, rash, dry skin, seborrhea, joint pain; cardiovascular arrhythmias and orthostatic hypotension.
Other rare reactions of Sernal drug are: Decreased concentration, depression, hypertonic reactions, memory loss, paresthesia, diarrhea, flatulence, gastritis, black stools, acne, hair loss, weight gain or loss, hyponatremia, diabetes risk, amenorrhea, gynecomastia, bed-wetting, bloody urination, vaginal bleeding, nosebleeds, purpura, anemia and chills.
If these symptoms are encountered, the patient should stop using Sernal and notify the doctor for appropriate treatment.
4. Caution
Sernal should be used with caution in elderly patients, debilitated people, impaired liver and kidney function and people prone to hypotension. These cases are more likely to experience side effects than the general population. With caution in patients with cardiovascular problems, cerebrovascular disease, history of epilepsy, spasticity, Parkinson's syndrome. The recommended dose of the drug is at a low dose. For pregnant and lactating women, those who are driving a car or operating machinery, it is not recommended to use the drug..
5. Drug interactions
Use caution when combining Sernal with drugs that act on the central nervous system and alcohol because of the potential for more serious reactions. CYP2D6 inhibitors, such as SSRIs, may increase plasma concentrations of risperidone. Carbamazepine and other CYP3A4 inducers: This combination will reduce the antipsychotic activity of risperidone in plasma. Therefore, it is necessary to adjust the amount of Sernal or discontinue the use of CYP3A4 inducers. Antihypertensives: Because Risperidone can cause hypotension, the use of Sernal should be closely monitored while patients are also taking antihypertensives to avoid severely low blood pressure. Risperidone should not be used in combination with the diuretic Furosemide in elderly patients with dementia because of the potential for serious side effects with a high mortality rate. Abametapir: The serum concentration of Risperidone may be increased when it is combined with Abametapir. Abatacept, Abiraterone, Abiraterone and Acalabrutinib: The metabolism of Risperidone may be increased when combined with drugs above Acarbose: The therapeutic effect of Acarbose may be decreased when used in combination with Risperidone. Acebutolol: Acebutolol may increase adverse reactions or the severity of QTC prolongation may be increased when Risperidone is combined with Acrivastine. Acenocoumarol: The risk or severity of adverse events may be increased when Risperidone is combined with Acenocoumarol Acetaminophen: The metabolism of Risperidone may be decreased when combined with Acetaminophen. Acetohexamide: The therapeutic efficacy of Acetohexamide may be reduced when used in combination with Risperidone. Acetylsalicylic acid: The risk or severity of hypertension may be increased when Risperidone is combined with Acetylsalicylic acid Aclidinium: Risperidone may increase the central nervous system depressant (CNS depressant) activities of Aclidinium. . Acrivastine: The risk or severity of QTC prolongation may be increased when Risperidone is combined with Acrivastine. Albiglutide: The therapeutic efficacy of Albiglutide may be reduced when used in combination with Risperidone. To avoid interactions, before being prescribed Sernal, the patient should inform the doctor about the drugs they are using, including functional foods. The doctor will base on that to prescribe the appropriate Sernal.
Above is all information about Sernal drug, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Note, Sernal is a prescription drug, you need to use it as prescribed by your doctor, absolutely do not self-treat at home.
