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The drug Seosacin contains ambroxol hydrochloride and clenbuterol and is available in oral syrup form. Seosacin is indicated in the treatment of bronchospasm or phlegm caused by bronchial asthma or pulmonary emphysema, bronchitis. Using Seosacin can cause some unwanted side effects such as anxiety, restlessness, tremor. Therefore, before using Seosacin, patients need to carefully learn information and advice from the treating doctor.1. Mechanism of action of the drug Seosacin
The brand name Seosacin contains ambroxol hydrochloride and clenbuterol as ingredients.Ambroxol belongs to the group of drugs that regulate mucus secretion and dissolve phlegm. It also acts on the gel phase of mucus by severing the disulfur bonds of glycoproteins, thereby helping to loosen phlegm more easily. When Ambroxol enters the body, it is well absorbed from the gastrointestinal tract and reaches maximum plasma concentrations about 2 hours after administration. Therefore, bioavailability of the drug may account for about 70%. The half-life is about 7.5 hours and the drug is eliminated mainly in the urine. Clenbuterol has the ability to stimulate both the heart and the central nervous system. At the same time clenbuterol has similar effects on the body as epinephrine and amphetamine. This substance is also a beta-agonist and in contrast to beta-blockers, i.e. clenbuterol can increase the components epinephrine and adrenaline. This increase can lead to a variety of effects such as rapid fat burning, body sensitivity, etc.
2. The effect of the drug Seosacin
The compound Ambroxol in the drug Seosacin acts as a metabolite and its effect is similar to that of Bromhexin. Ambroxol is considered to have expectorant and mucolytic effects. However, this role has not been specifically demonstrated. But some current literature has also shown the effect of Ambroxol to help improve symptoms and reduce some exacerbations of pneumonia. Most recently, the literature also suggests that Ambroxol is effective for people with mild to moderate obstructive pulmonary disease, but in more severe cases there is no proven benefit. conspicuous way. In addition, the use of nebulizer with Ambroxol can be beneficial in patients with alveolar proteinosis who refuse to wash the bronchi. The compound clenbuterol has a decongestant and bronchodilator effect. The researchers demonstrated that the drug's decongestant function lowers blood pressure while the drug dilates the bronchi by widening the oxygen-carrying vessels. As a result, the volume of oxygen in the blood will increase.3. Indications and contraindications for the use of Seosacin
Seosacin is indicated for treatment in the following cases:Treatment of bronchial asthma accompanied by signs of bronchospasm or phlegm. Treatment of acute or chronic bronchitis. Treatment of pulmonary emphysema. Use for patients before or after surgery. In the case of an emergency to avoid lung complications in the elderly, this medicine can be used. Treatment for people with respiratory diseases such as sinusitis or exudative otitis media, dry rhinitis. However, the drug Seosacin may be contraindicated in cases of hypersensitivity to the components of the drug or cases of advanced gastric and duodenal ulcers.
4. Dosage and usage of Seosacin
Seosacin is used for both adults and children:For infants up to 8 months old, the use of the drug will depend on the weight and usually apply whether 2.5 ml is equivalent to 1/4 pack and each Medicines should be administered 12 hours apart. For children from 8 months to 2 years old, the use of the drug will depend on the weight and usually apply whether 5ml is equivalent to 1/2 pack and each dose should be 12 hours apart. For children from 2 years old to 4 years old, the use of the drug will depend on the weight and usually apply whether 7.5ml is equivalent to 3/4 sachets and each dose should be 12 hours apart. For children from 4 to 6 years old, the use of the drug will depend on the weight and usually apply whether 10ml is equivalent to 1 pack and each dose should be 12 hours apart. For children from 6 to 12 years old, the use of the drug will depend on the weight and usually apply whether 15ml is equivalent to 1.5 sachets and each drug use should be 12 hours apart. For children over 12 years old and adults, use Seosacin 20ml equivalent to 2 packs and each use should be 12 hours apart. Seosacin is used orally directly. For maximum effectiveness, patients should take the drug with meals.
The recommended therapeutic dose above is for reference only, so before using Seosacin to treat patients, it is necessary to consult a doctor.
In case the patient accidentally takes an overdose of Seosacin than prescribed and has some signs of unwanted side effects, it is necessary to take the patient to an emergency at the nearest medical facility for assistance. timely medical assistance to help patients overcome dangerous conditions.
If the patient takes Seosacin and misses a dose, the missed dose can be used as soon as he remembers. However, if the interval between the missed dose of Seosacin and the next dose is close, the patient can skip the missed dose and take the next dose. Patients should also note that the dose of Seosacin should not be doubled because it may cause drug overdose and unwanted side effects that affect the patient's current health.
5. Unexpected side effects and some notes when using Seosacin thuốc
Seosacin can cause unwanted side effects affecting the body's organ systems:For the central nervous system, Seosacin can cause nervous tension, headache, dizziness, loss of consciousness. sleepy or agitated. For the musculoskeletal system, there may be symptoms such as muscle twitching, tremors. For the circulatory system, there may be changes in blood pressure, arrhythmias, and peripheral vasodilation. Some other side effects such as elevated liver enzymes, digestive disorders, loss of appetite, fatigue, bloating. Some notes when using Seosacin:
Interaction Seosacin should not be used in combination with antibiotics because it can increase lung parenchyma, causing an increase in antibiotic concentration in the body. ACE inhibitors should also not be used with Seosacin. Therefore, before using Seosacin, the patient should provide a complete list of previously used drugs including prescription or non-prescription drugs or herbs. Seosacin should be used with caution in people such as the elderly, people with hyperthyroidism, gastrointestinal ulcers leading to hemoptysis, or patients with diabetes, severe renal failure or related bronchial asthma. For blood calcium, pregnant and lactating women should be cautious and carefully analyze the risks and benefits that may be encountered when using the drug. Therefore, in case of necessity and indicated to use the drug. Using drugs, these subjects should be cautious, especially in the first 3 months of pregnancy. During use should be regularly monitored by a doctor, so that if a situation occurs, medical assistance can be timely.
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