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Contrast-induced acute renal failure is a condition in which acute renal failure occurs or the degree of renal failure increases after contrast agent administration. This risk usually appears within 24-48 hours after the administration of contrast medium, the highest increase in creatinine after 5-7 days and most cases return to normal after 7-10 days.
1. What is Contrast?
Contrast is a solution containing iodine, which is injected into the body when taking pictures in magnetic resonance imaging, ultrasound or X-ray to increase the contrast level of structures or body fluids when taking pictures. imaging (the structure or lesion will appear bright white on a CT scan, helping to distinguish it from other surrounding structures). Contrast is often used to clearly define the blood vessels and organs of the digestive system.
Contrast has 3 types:
Contrast with low osmolarity such as: Iopamidol, ioversol, iohexol,... Contrast with normal osmolarity: Iodixanol. Contrast with high permeability such as Lothalamate, Diatrizoatem.
2. Contrast-induced acute renal failure
Contrast-induced acute renal failure is a condition in which acute renal failure occurs or the degree of renal failure increases after contrast agent administration.
Contrast-induced acute renal failure is diagnosed when an increase of 25% or > 0.5 mg/dl (44.2 mmol/l) from baseline creatinine occurs. This risk usually appears within 24-48 hours after the administration of contrast medium, the highest increase in creatinine after 5-7 days and most cases return to normal after 7-10 days.
Besides, some of the following factors will increase the risk of contrast-induced acute renal failure:
Age: People over 70 years of age, if using contrast, will increase the risk of acute renal failure. Low glomerular filtration rate: This factor increases the risk of acute renal failure if contrast is used. Pre-existing cardiovascular disease, diabetes. Must take medication for hypertension Must use Metformin Must use large volumes of contrast agent
3. Some other risks when using contrast agents
Anaphylaxis: This is a reaction after taking the drug within 1 hour. Symptoms include: itching, angioedema, dyspnea, hypotension, shock, loss of consciousness. Thyroid storm: This is a serious condition in people with hyperthyroidism, so when using contrast, the patient must inform the doctor about the medical history. Harm to the fetus: Pregnant women need to consider carefully, choose other methods such as ultrasound, X-ray often with protective clothing.
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