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Sastan-H is a drug belonging to the group of cardiovascular drugs with the main ingredients being Losartan potassium and Hydrochlorothiazide used in the treatment of cardiovascular diseases.1. What is Sastan-H?
Sastan-H is a cardiovascular drug with the main ingredients being losartan potassium and hydrochlorothiazide. Losartan is an angiotensin II receptor antagonist that reduces the combined risk of cardiovascular death, stroke, and myocardial infarction in hypertensive patients with left ventricular hypertrophy and prevents Renal complications in type 2 diabetic patients with proteinuria. Hydrochlorothiazide belongs to the group of thiazide diuretics with antihypertensive effects through a reduction in plasma volume and extracellular fluid associated with sodium diuresis. Next, the antihypertensive effect depends on the decrease in peripheral resistance by the gradual adaptation of blood vessels to the decrease in sodium ion concentration during drug administration. Therefore, the antihypertensive effect of hydrochlorothiazide manifests itself 1-2 weeks after dosing, and a rapid diuretic effect can be seen within a few hours. In addition, hydrochlorothiazide has the effect of increasing the effectiveness of other antihypertensive drugs.2. Effects of Sastan-H
The active ingredient Losartan contained in the drug Sastan-H is an antagonist at the Angiotensin II receptor with strong vasoconstriction ability. This ingredient is used to treat hypertension and to reduce the risk or events in hypertensive patients with left ventricular hypertrophy. In addition, it also helps to reduce the mortality from myocardial infarction and has a protective effect on kidney function in patients with type 2 diabetes with proteinuria. The active ingredient Hydrochlorothiazide belongs to the group of thiazide diuretics, which inhibit the reabsorption of Na+ and Cl- ions in the distal tubule, helping to increase salt and water excretion. Thanks to this mechanism, the drug helps to reduce the volume of plasma and extracellular fluid, thereby helping to lower blood pressure.3. Indications of the drug Sastan- H
Sastan-H is indicated for use in the following cases:Treatment of high blood pressure and reducing the risk of life-threatening cardiovascular diseases. Prevention of progression of renal complications and renal protection in patients with type 2 diabetes with proteinuria.
4. Instructions for using Sastan-H
The drug is used orally and absolutely should not be chewed or broken because it can reduce the effectiveness of the drug. In addition, patients can use it in combination with some other antihypertensive drugs as indicated. doctor's decision.Recommended dosage is as follows:
The starting dose is 2 tablets/day. After 3 - 6 weeks, if blood pressure cannot be controlled, it can be increased to 2 tablets / time x 2 times / day. In case of missed dose, do not take additional medicine as soon as you remember. When it is almost time for your next dose, you can skip the missed dose and take your next dose as scheduled. Never double the dose.
5. Contraindications to the use of Sastan-H
Cases where Sastan-H cannot be used include:Patients with liver failure or anuria. People with a history of hypersensitivity to any of the ingredients of the drug.
6. Some notes when using Sastan-H
During the use of the drug may appear some unwanted side effects such as headache, angioedema, dizziness, tachycardia, laryngeal edema, ... When the patient has abnormal manifestations and signs If there is a bad change, the patient should immediately contact the doctor for timely intervention.Currently, there are no reports of drugs interacting with Sastan - H when used at the same time. However, patients need to list the drugs and supplements they are taking to the doctor to ensure safety and use them correctly.
About the level of safety when used for pregnant and lactating women, there are no accurate data yet. Therefore, it is necessary to consult a doctor before deciding to use it to weigh the benefits of treatment against possible risks.
Sastan-H drug can cause headaches, dizziness, affecting the ability to drive and use machines, so caution should be exercised when using the drug in these subjects.
To ensure optimal blood pressure regulation, patients need to combine with diet, supplement with lots of green vegetables, fruits and light exercise, reasonable living, and limit food. eating grease and using stimulants.
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