Uses of the drug Rossar

This is an automatically translated article.

Rossar is used to treat mild to moderate hypertension, especially in patients with cough caused by taking Angiotensin-converting enzyme inhibitors. Learn some information about uses, doses and precautions when using Rossar to help patients use the drug safely and effectively.

1. What is rossar?


Rossar belongs to the group of cardiovascular drugs, made in the form of film-coated tablets, packing box of 3 blisters x 10 tablets. The ingredient Losartan potassium 50mg in Rossar belongs to the class of antihypertensive drugs, an angiotensin II receptor antagonist. Angiotesin II, formed from angiotensin I in the enzymatic reaction, angiotensin converting enzyme (ACE), is a potent vasoconstrictor and an important component in the pathophysiology of hypertension. Angiotensin II also stimulates the adrenal cortex to secrete aldosterone.

2. What are the effects of Rossar?

Rossar is used to treat mild to moderate hypertension, especially in patients with cough caused by taking Angiotensin-converting enzyme inhibitors.
Rossar drug helps to reduce as well as well control blood pressure, prevent the risk of stroke, kidney and eye related damage. The drug Rossar can be used alone or in combination with other drugs, depending on the treatment regimen proposed by the doctor.

3. How to use, dose of Rossar


Reference dose of Rossar is as follows:
The usual starting dose of Rossar is 50mg per day. The dose may be increased to 100mg once daily or in 2 divided doses. A lower starting dose of Rossar (25 mg daily) is recommended for the elderly over 75 years of age, those with intravascular fluid loss, and moderate to severe hepatic/renal impairment (creatinine clearance less than 20 mL/min). How to take the drug Rossar:
Rossar taken orally with a glass of water just enough. Rossar can be taken when hungry or full. Note: The dose of Rossar above is for reference only. The specific dose of Rossar will depend on the patient's condition and disease progression. To get the right dose of Rossar, patients need to consult their doctor/pharmacist.

4. Contraindications to taking the drug Rossar


Rossar drug should not be used in the following cases:
Patients with hypersensitivity to any ingredient of Rossar drug. Pregnant women. Do not combine Rossar with potassium-sparing diuretics. Contraindications are understood as absolute contraindications, which means that for any reason, the contraindication is flexible enough to use Rossar.

5. Note when using the drug Rossar


When appointing Rossar drug, special attention and caution should be taken in the following cases:
Use Rossar with caution in patients with renal artery stenosis, kidney and liver failure. Patients with intravascular volume depletion may experience hypotension during treatment with Rossar. Therefore, this should be corrected before Rossar is used or a lower starting dose is used. Because hyperkalemia may occur with the use of Rossar, serum potassium levels should be controlled, especially in the elderly and in patients with renal impairment. Avoid co-administration of Rossar with potassium-sparing diuretics. It is not known whether Rossar is excreted in human milk. Because of the potential for adverse drug reactions in the nursing infant, a decision should be made whether to discontinue nursing or to discontinue Rossar depending on the importance of the drug to the mother. Rossar can cause dizziness, headache, so caution should be exercised when driving a vehicle or operating machinery.

6. Side effects of the drug Rossar


Common side effects:
Lower blood pressure. Insomnia, dizziness. Hyperkalemia. Diarrhea, indigestion. Decrease in hemoglobin and hematocrit levels. Back/leg/muscle pain. Lower serum uric acid if used in high doses. Cough, nasal congestion, sinusitis. Uncommon side effects:
Orthostatic hypotension; Chest pain; Grade II A-V block; Palpitations, sinus bradycardia; Fast heart beat; Swollen face, red face. Anxiety, ataxia, confusion; Depression; Migraine headache ; Sleep disorders; Fever, dizziness; Hair loss; Inflammation and dryness of the skin; red rash; Light sensitivity ; Itching, hives; Bruises, rashes. Gout. Loss of appetite, constipation, flatulence; Vomiting, loss of taste; Gastritis. Decreased sexual function, increased urination. Increased liver function and bilirubin. Paresthesia, tremor; Bone pain, muscle weakness, joint edema; Conjunctivitis; Reduced vision, heat and eye pain. Tinnitus. Urinary tract infections ; Increased creatinine or urea levels. Shortness of breath; Bronchitis; Epistaxis; Rhinitis; Airway congestion; Throat discomfort; Sweat a lot. If there are any unusual symptoms suspected of using Rossar, the patient should notify the treating doctor/pharmacist for timely treatment.

7. Interactions with other drugs


The following are some possible drug interactions when taken concomitantly with Rossar:
The antihypertensive effect of Rossar is enhanced by concomitant administration with other antihypertensive agents. Concomitant use of Rossar with potassium-sparing diuretics, potassium supplements or potassium-containing salts may cause hyperkalemia. Rossar is metabolised by the cytochrome P450 enzyme system and may affect some drugs metabolized by these enzymes. Concomitant administration of cimetidine increased the AUC of the active ingredient losartan in Rossar by approximately 18%. Phenobarbital reduces the concentration of losartan in Rossar and its active metabolite. Ketoconazole inhibits the conversion of losartan in Rossar to its active metabolites. To avoid unwanted interactions when using Rossar, please inform your doctor/pharmacist of all medications, dietary supplements, vitamins and herbs... you are taking.
The basic information about the drug Rossar in the above article is for reference only. Because Rossar is a prescription drug, patients should not use it on their own, but need to contact a specialist directly for a suitable prescription to ensure safety for health. Store the medicine in a cool, dry place, the temperature is below 30 degrees Celsius, avoid direct sunlight and keep out of reach of children and pets.

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