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Sancefur belongs to the group of musculoskeletal drugs and is a fairly reasonable choice for patients who are experiencing problems with osteoporosis. Complying with the indications and doses of Sancefur will help patients improve treatment efficiency and ensure safety for health.
1. What is Sancefur?
Sancefur drug belongs to the group of muscle - bone - joint drugs that affect bone metabolism, with registration number VN-18196-14, manufactured by Pharmathen S.A Company - Greece.
Sancefur medicine includes the following ingredients:
Main ingredient Risedronate sodium 35mg; Excipients: Starch pregelatinized, magnesium stearate, microcrystalline cellulose, lactose monohydrate, titanium dioxide. Sancefur is prepared in the form of film-coated tablets with a content of 35mg, a box of 1 blister of 4 tablets. Sancefur is recommended for use by people 18 years of age and older.
2. What does Sancefur do?
Sancefur medicine contains the ingredient Risedronate, which is a derivative of the Pyridyl Bisphosphonate group, which has an anti-osteoporotic role. Physiologically, bone turnover is a balance between the two processes of bone formation and bone resorption, performed by osteoclasts, osteoblasts, and basal cells. At a certain age (about after 40 years old) osteoclasts are overactive, leading to osteoporosis.
According to research, Risedronate has anti-osteoporosis effect. The effects of this active ingredient were monitored by measuring biochemical markers in bone turnover in two groups of subjects. Results:
Postmenopausal women: Biochemical markers decreased within 1 month, reaching a maximum in 3 -6 months. Men with osteoporosis: Biochemical markers decreased at 3 and 24 months. Sancefur is indicated for use in the following cases:
Postmenopausal women with osteoporosis. Men are at higher risk of fractures. Prevention of osteoporosis in postmenopausal women.
3. How to use Sancefur
Should swallow the tablet whole, do not chew or suck the tablet. Sancefur should be taken in an upright position with a glass of plain water, should not lie down within 30 minutes after taking the drug so that the medicine goes to the stomach easily. Should not be taken with food and other drugs (vitamins, calcium, iron, antacids, laxatives, ..) or sweet drinks, tea, coffee, it is best to drink at least 30 minutes before eating. The drug should be taken on a certain day of the week and maintained throughout the course of treatment. Calcium and vitamin D supplements should be added if dietary intake is inadequate.
4. Dosage of the drug Sancefur
Dosage for adults is 1 tablet of 35 mg per week.
Elderly: No dose adjustment is required because bioavailability, distribution and elimination in people over 60 years of age are similar to those in young adults. Patients with renal impairment: No dose adjustment is required in patients with mild to moderate renal impairment. Do not use the drug in patients with severe renal impairment. Children: The safety and effectiveness of Sancefur 35mg have not been established in children and adolescents. Treatment for missed dose:
This is a prescription drug. So take the medicine exactly as prescribed by your doctor or according to the directions on the label. Never use more or less than indicated. You should choose a fixed day of the week to take your medicine, you can set a bell to remember or write on a schedule to avoid forgetting the medicine. If you forget to take it the next day. The second example is the dosing schedule. If you forget, take 1 pill on Tuesday. Then the next 2nd week still take it as scheduled. Do not stop taking the medicine on your own without consulting your doctor. Treatment of Overdose:
No special information is available on the treatment of drug overdose. After a severe overdose, a decrease in serum calcium may be observed. Signs and symptoms of hypocalcaemia may also occur in this patient. Milk or antacids containing magnesium, calcium or aluminum should be used to bind risedronate and reduce the absorption of risedronate sodium. In case of severe overdose, gastric lavage may be required to remove the absorbed drug.
5. Contraindications of the drug Sancefur
Do not use Sancefur for people who are sensitive to any of the ingredients of the drug. Pregnant and lactating women. Do not use for small children. Patients with hypocalcemia, patients with severe renal impairment (creatinine clearance <30ml/min).
6. Notes when using Sancefur
Use Sancefur with caution in patients with liver failure or elevated liver enzymes. Avoid taking any other medicines for at least 30 minutes after taking Sancefur. Try to quit or minimize smoking during treatment with Sancefur, as smoking can reduce bone mineral density, increasing the risk of fractures. Avoid alcohol, as it can cause bone loss. Food, drinks and products containing magnesium, iron, calcium or aluminum can affect the absorption of active Bisphosphate and should not be taken at the same time as taking the drug. Therapeutic efficacy of Bisphosphate in relation to low bone mineral density or fracture. Because the drug contains lactose, patients with problems with galactose intolerance, lactase deficiency or glucose malabsorption should not take this medicine. Effects of drugs on drivers and operating machines: Use caution when using Sancefur because r Sancefur has side effects such as headache, musculoskeletal pain.
7. Interactions with other drugs
Drugs containing multivalent cations such as calcium, magnesium, iron and aluminum: When used together with Sancefur, the effect of the drug decreases, reducing the effectiveness of treatment. Sancefur can be used concurrently with an estrogen supplement after careful consideration (for women). Acetylsalicylic acid or nonsteroidal anti-inflammatory drugs (NSAIDs) may increase the adverse effects/toxicity of bisphosphonate derivatives, increase the risk of gastrointestinal ulceration, and increase the risk of nephrotoxicity. Histamine H2-receptor antagonists may increase the serum concentration of risedronate, so the combination should be avoided. Proton pump inhibitors increase the serum concentration of risedronate causing many side effects and toxicity to the body.
8. Side effects of the drug Sancefur
When using Sancefur in the treatment of osteoporosis, patients may experience some of the following side effects:
Allergic reactions: rash, itching, rash, swelling of the face, swelling of the throat, difficulty breathing, burning in eyes, headache,... Digestive symptoms: abdominal pain, heartburn, stomach burning pain, diarrhea, dyspepsia, nausea, gastritis, esophagitis, dysphagia, duodenitis, esophageal ulcers,... Osteoarthritis symptoms: musculoskeletal pain, back pain, muscle pain, numbness, stinging,... More severe can lead to leukopenia and liver enzyme disorders. If you experience any unpleasant symptoms (which may or may not be mentioned above) after taking the drug, the patient should immediately report it to the treating doctor for treatment advice, timely treatment and drug change if necessary. set.
Above is information about uses, doses and notes when using Sancefur medicine. To ensure safety for health and maximize the effectiveness of treatment, patients need to take Sancefur medicine exactly as directed by their doctor.
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