This is an automatically translated article.
Lomazole Inj drug belongs to the group of diuretics, which is prepared in the form of lyophilized powder for injection 40mg. The main ingredient of Lomazole Inj is Omeprazole sodium, which is used in the ineffective oral treatment of duodenal ulcer, gastric ulcer, ulcerative esophagitis and Zollinger-Ellison syndrome. However, the drug Lomazole Inj can bring some side effects, so it is necessary to find out carefully before using the drug.
1. Mechanism of action of the drug Lomazole Inj
Lomazole Inj drug has a proton pump inhibitor effect to help reduce acid secretion in the stomach, and at the same time reduce the pH of the stomach and the symptoms of stomach pain for patients.
The Omeprazole component in Lomazole Inj can be converted to an active form in a highly acidic environment, however, it is only effective when it is converted in the parietal cells of the stomach. Modification of the drug before absorption by stomach acid will make the drug ineffective. After the drug is absorbed into the parietal cells with H + effect, the drug is converted into a form that inhibits the enzyme H + K + ATPase, leading to a decrease in gastric acid secretion.
2. Indications and contraindications for the use of Lomazole Inj
Lomazole Inj is indicated in the treatment of gastroesophageal reflux disease, peptic ulcer disease or Zollinger Ellison syndrome. Lomazole Inj can also be combined with antibiotics to kill the H.pylori bacteria that cause stomach infections. In addition, the drug can also be used in the treatment of frequent heartburn.However, Lomazole Inj drug may be contraindicated in cases of hypersensitivity to the drug's components. Or cases of angioedema, bronchospasm, acute interstitial nephritis, urticaria.
3. Dosage and how to use Lomazole Inj
Lomazole Inj is mixed with 10ml of solvent and injected slowly for not less than 2.5 minutes, at a rate not exceeding 4ml/min. The recommended dose of Lomazole Inj is 40mg/day. If additional IV injections are needed for 3 days, the patient should reduce the dose to 10 to 20 ml/day.
For the treatment of Zollinger Ellison syndrome, the dose of Lomazole Inj will usually be adjusted according to the patient's response.
For patients with liver failure, kidney failure or the elderly, no dose adjustment is required. amount of Lomazole Inj medicine if not prescribed by your doctor.
Note: The above recommended therapeutic dose for Lomazole Inj is for reference only. Therefore, before using Lomazole Inj, patients should be prescribed by a doctor.
4. Management of missed dose and overdose of Lomazole Inj
If you miss a dose of Lomazole Inj, use the missed dose as soon as you remember. However, if the interval between the missed dose of Lomazole Inj and the next dose is too close, skip the missed dose. Patients should not use a double dose of Lomazole Inj, because it can cause an overdose. To overcome the missed dose of Lomazole Inj, the patient can set an alarm or ask a loved one to remind him.
In case of accidentally using Lomazole Inj drug in excess of prescribed and showing some unwanted signs, the patient should be taken to the emergency room immediately. However, family members can apply some preliminary treatment measures when poisoning with Lomazole Inj such as: gastric lavage and vomiting. The next step is to take the patient to a medical facility to treat the symptoms.
5. Unexpected side effects when using Lomazole Inj
Lomazole Inj medicine may cause some unwanted side effects during treatment. However, with each case, the side effects of Lomazole Inj can occur in varying degrees from mild to severe.
Some common side effects caused by Lomazole Inj include: constipation, bloating, nausea and vomiting, headache, rash, hives, itching, swelling of the face, throat, tongue and lips.. These side effects may occur at the beginning of treatment or after increasing the dose of Lomazole Inj. Usually, side effects from Lomazole Inj can be transient or subside over time.
However, in some cases Lomazole Inj can cause serious unwanted side effects with rare reactions. These reactions may appear after just a few minutes of using Lomazole Inj or longer for a few days. When serious side effects appear such as: irregular heartbeat, dizziness, muscle spasms, increased risk of wrist and spine fractures, excessive fatigue, etc., the patient should stop using the drug. Lomazole Inj and seek medical assistance immediately.
Some notes during the use of Lomazole Inj:
For pregnant and lactating women, caution should be exercised when using Lomazole Inj. Patients should be advised to use Lomazole Inj from their doctor and carefully analyze the benefits and risks before using the drug. Lomazole Inj may change how it works as well as increase its side effects. Therefore, to avoid this situation, the patient should provide the doctor with a list of previous medications including prescription drugs, over-the-counter drugs and herbs... Lomazole Inj may cause dizziness during the procedure. drug use. Therefore, for those who need to be alert, awake or drive a vehicle or machine, caution should be exercised when using Lomazole Inj. Above is important information about Lomazole Inj, patients should carefully read the instructions for use and use according to the dose prescribed by the doctor to achieve the best effect.
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