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Safaria drug is made in the form of vaginal tablets, used to treat bacterial and vaginal yeast infections, vaginitis caused by Trichomonas, Candida,... To understand more about the composition, effects and usage of the drug. , please read the article below.
1. What is Safaria?
Safaria drug is prepared in the form of vaginal suppositories, containing the following active ingredients:
Metronidazol 225mg. Chloramphenicol 100mg. Nystatin 75mg. Metronidazole is a commonly used antibiotic that belongs to the Nitroimidazole class of antibiotics. Metronidazole is commonly used to treat infections of the gastrointestinal tract as well as those caused by Trichomonas and Giardia, parasitic infections.
Chloramphenicol has a relatively simple structure and was the first broad-spectrum antibiotic discovered. Bacteriostatic effect, works by interfering with bacterial protein synthesis. Nystatin is a Polyene ionophore antifungal drug, with broad-spectrum fungicidal and fungicidal activity, used to treat infections of the skin, mucous membranes, and gastrointestinal tract, especially those caused by Candida fungi. .
2. Uses of the drug Safaria
Safaria drug is indicated in the following cases:
Treatment of mixed vaginal infections, itching caused by bacterial and fungal infections, vaginitis with white discharge, vaginitis caused by Trichomonas. Treatment of fungal diseases of the vagina, vulva and Candida.
3. Usage- Dosage of drug Safaria
How to use:
Use Safaria through the vagina. Before placing, place the tablet for about 5-10 minutes in the freezer compartment. Wash hands and vagina. Use your finger to push the pill as deep into the vagina as possible to get the best treatment results. When the symptoms are relieved, still use Safaria drug as the course of treatment prescribed by the doctor. Take the medicine at the same time of day to avoid missed doses. Only use Safaria when prescribed by a doctor, do not use it on your own. Dosage:
In case of acute vaginitis: 1 tablet each time, 1-2 times/day (best in the morning and evening). After that, the maintenance dose is set 1 tablet/time (evening) within 6-8 days. In case of chronic vaginitis: 1 tablet each time (evening), use continuously for 14 days. In case of vaginal yeast infection: 1 tablet each time (evening), use continuously for 7-10 days. In case of missed dose:
Take as soon as you remember, if it is almost time for the next dose, skip the missed dose and use the next dose as directed. Do not take extra medicine to make up for the missed dose. In case of overdose:
When using an overdose, there may be peripheral sensory neuropathy, leukopenia, symptoms will disappear when stopping use. Nausea, vomiting, urine staining (due to Metronidazol overdose), diarrhea. Treatment of overdose: Discontinue use and treat symptomatically.
4. Contraindications to Safaria
Cases with a history of hypersensitivity to Metronidazol, Chloramphenicol, Nystatin and any of the excipients contained in Safaria.
5. Side effects when using Safaria
When using Safaria medicine can cause the following side effects: Rash, slight burning, irritation, burning in the vaginal area, vaginal itching (most often when there is an open lesion or when starting treatment). treatment). If these symptoms are mild, Safaria can be continued. But if more severe conditions appear, notify your treating doctor for prompt care. The list of possible side effects is not exhaustive, if any unusual symptoms appear, please inform your doctor.
6. Interaction with drugs Safaria
Vaginal use of Safaria, when used in combination with topical spermicidal birth control methods, may reduce or eliminate the effectiveness of this method. Increased effect of oral anticoagulants (especially Warfarin) should be avoided. When combined with the drug Disulfiram can cause neurotoxicity such as confusion, psychosis. Phenobarbital: Increases metabolism and elimination of the active ingredient Metronidazole in the drug, so Safaria is eliminated faster. Metronidazole will increase serum lithium levels, causing toxicity (especially in patients with high blood lithium levels). Vecuronium: When combined with Safaria, the effect of Vecuronium will be increased.7. What should be noted before using Safaria?
Avoid sex during treatment with Safaria. Sexual partners should be treated to avoid reinfection. Use the correct medication for the treatment even though the symptoms are in remission. Re-examination after 4 weeks if no improvement. Safaria may reduce the reliability of mechanical contraceptives such as diaphragms, condoms, etc. Caution should be exercised in patients with severe liver dysfunction. During treatment, it is necessary to avoid sources of reinfection or infection.
8. Notes on pregnant and lactating women when using Safaria
Pregnancy:
Chloramphenicol: In women during the first 3 months of pregnancy, there are not enough clinical data on the effects of Chloramphenicol. Therefore, your doctor will weigh the benefits and risks to use. Metronidazole: There are some studies that indicate that Metronidazole may increase birth defects in the fetus, when taken during the first 3 months of pregnancy. Therefore, during early pregnancy, Safaria should not be used. Nystatin: Not recorded. Lactation:
Chloramphenicol: Caution should be exercised in nursing mothers, as there are insufficient data to demonstrate whether Safaria is excreted in human milk. Nystatin: Not excreted in breast milk. Metronidazole: May be rapidly excreted into breast milk, breastfeeding should be discontinued during treatment. Above are answers to questions about what Safaria is, its uses and notes when using it. Patients should strictly follow the instructions on dosage and use of drugs from medical professionals to achieve the best treatment effect.
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