This is an automatically translated article.
Sadetabs is a prescription drug indicated for the local treatment of acute or chronic intestinal amoebic inflammatory disease; Genital tract infections or prophylaxis in case of nonspecific vaginitis.
1. What is Sadetabs?
Sadetabs is a drug used for the local treatment of the following conditions:
Inflammation caused by amoebiasis in and out of the intestine in acute or chronic form; Inflammatory diseases of the genital tract; Prophylactic treatment in patients with nonspecific vaginitis. One Sadetabs tablet contains:
Neomycin sulphate 83mg; Clotrimazole 100mg; Metronidazole 500mg; Other excipients are enough for 1 tablet to put Sadetabs.
2. Effects of the main ingredient in Sadetabs
Sadetabs suppositories contain antibiotics that are sensitive to bacteria that cause gynecological infections. The effect of each ingredient is as follows:
Ingredients Neomycin Neomycin is a broad-spectrum aminoglycoside antibiotic that inhibits gram-negative and gram-positive bacteria such as: Escherichia coli, Klebsiella, Enterobacter, Pseudomonas aeruginosa, Haemophilus influenzae, Bacteroides , Enterobacter spp causes infections of the skin, mucous membranes, eyes and ears. Neomycin's mechanism of action is to bind to 30S ribosomal subunits in bacterial cells, thereby inhibiting protein synthesis and preventing the growth and survival of pathogenic bacteria. Clotrimazole is a broad-spectrum antifungal agent that inhibits yeast growth by altering cell membrane permeability. Clotrimazol is commonly used topically in the treatment of systemic tinea, toenail fungus caused by Trichophyton and Epidermophyton; Vaginal thrush , Candida diaper rash and vitiligo .
Ingredients Metronidazol This ingredient belongs to the group of antibiotics Nitroimidazole has broad antibacterial activity against anaerobic bacteria and amoebae.
After oral administration, Metronidazol penetrates into the cells of bacteria, inhibits the synthesis of nucleic acids and produces harmful metabolites that damage the DNA of pathogenic bacteria in the body.
Therefore, this active ingredient is often used to treat gastrointestinal infections, Giardia and infections caused by amoeba, Trichomonas vaginalis, ... on female subjects and the patient's sexual partners.
3. Dosage of Sadetabs
Treatment of vaginal thrush infection: Put one Sadetabs pill every day, treat for 7 days. Additional oral treatment with metronidazole in women and their sexual partners, because of the potential for sexually transmitted disease; Treatment of vaginitis caused by Candida yeast infection: One tablet for a 7-day course of treatment. It is possible to supplement the oral route with Triazoles; Treatment of bacterial vaginosis: One tablet sets the course of treatment for 7 days. Complementary oral therapy with metronidazole in women; Vaginitis caused by foreign agents such as tampons, irritants, spermicides or antibiotics causes infection. The use of Sadetabs is contraindicated in cases of hypersensitivity to any of its components.
4. How to use Sadetabs
As a vaginal medication, "can I have sex with Sadetabs" is a question many women have. Here's how to use Sadetabs:
Sadetabs vaginal suppositories should be taken at bedtime for optimal effectiveness; In the case of a vaginal yeast infection, it is necessary to treat both sexual partners; Avoid sex after placing Sadetabs; Do not take Sadetabs during your menstrual cycle. Wear tampons after putting on to prevent medicine from leaking into your pants; Leave the medicine in the fridge for 15 minutes before placing it so it doesn't get too soft. Steps to place Sadetabs:
Patients need to wash the intimate area with dilute saline or cleaning solution, then dry with a clean towel; Wash your hands with soap and water before inserting the medicine into the vagina. Note: Cut fingernails to avoid causing damage to the vagina during the insertion of the drug. A condom can be worn on the finger where the medication is inserted to make it easier to put on and to avoid bacterial vaginosis; Lie on your butt on a high pillow, bend your knees and extend your legs. Put the medicine at the vaginal opening, then push the medicine in until about 1 finger is gone, then stop. Close your legs and lie on your side and rest for at least 15 - 30 minutes so that the medicine does not fall out.
5. How to deal with missed dose, overdose of Sadetabs
Missed dose of Sadetabs:
Order Sadetabs as soon as you remember if it's still in the day; If the day has passed, skip the missed dose and take your next dose as usual. Do not take a double dose. Overdose of Sadetabs:
Sadetabs are used vaginally, using 1 tablet per day, so it is very unlikely that an overdose will occur; If you have any unusual symptoms after taking Sadetabs, notify your doctor immediately for prompt treatment.
6. Contraindications to the use of Sadetabs
Do not use Sadetabs drug on the following subjects:
Allergy to any ingredient of Sadetabs drug; Having a history of epilepsy should not use Sadetabs; The patient has severe liver and kidney dysfunction.
7. Note the use of Sadetabs in some subjects
Use of Sadetabs in pregnant women and nursing mothers:
Pregnant women: The Neomycin component in Sadetabs has been shown to cause fetal harm and irreversible congenital deafness. Therefore, do not use for women in the first 3 months of pregnancy. From the 4th month or more, pregnant women need to consult a doctor before use. Lactation: Although low concentrations of Sadetabs are absorbed into the blood and are excreted in human milk, excretion in breast milk is low. However, the drug should only be used in nursing women when prescribed by a doctor. Effects on ability to drive and use machines:
Use of Sadetabs does not affect the ability to use machines or drive.
8. Undesirable effects of the drug Sadetabs
Possible side effects when taking Sadetabs:
Common: Burning at the injection site, stinging sensation, vaginal discomfort, itching or hives; Uncommon: Dark urine, metallic taste in the mouth or nausea, dizziness, epigastric discomfort; Rare: Neomycin is toxic to the auditory nerve and kidney, so it should be used with caution in subjects with diseases related to these two organs. Side effects will vary from person to person depending on the individual case. If you experience any unusual symptoms, contact your doctor or pharmacist immediately for more specific instructions.
9. Sadetabs drug interactions
Medicines that should not be used with Sadetabs include:
Tuberculosis vaccine (BCG), cholera vaccine: Sadetabs will make these two vaccines ineffective; Busulfan, Carbocisteine, Disulfiram : Increases the side effects of the drug when used together; Progesterone: Decreased effect when used with Clotrimazol; Ataluren, Bacitracin, Foscarnet: Increases the harmful effects of Neomycin on the kidney; Mecamylamine: Neomycin may enhance the neuromuscular blocking effects of Mecamylamine. Interaction with food and drink:
Do not drink alcohol while using Sadetabs because it can cause symptoms such as nausea, vomiting, dizziness and abdominal pain. Inform doctors, pharmacists of drugs and functional foods being used for advice and appropriate adjustment.
You should store Sadetabs at room temperature, away from moisture and away from direct light. Do not store in the bathroom or in the freezer. Keep medicine out of reach of children and pets. You should not throw Sadetabs down the toilet or plumbing unless required.
In summary, Sadetabs is a topical treatment for acute or chronic intestinal and extraintestinal amoebic infections; Genital tract infections or prophylaxis in case of nonspecific vaginitis. To use drugs safely and effectively, patients should not self-medicate, but should consult a doctor or pharmacist before using.
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