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Rotaforte drug has the main ingredients Metronidazole and Spiramycin. Rotaforte is used in the treatment of oral infections such as: gingivitis, stomatitis, submandibular inflammation or crown inflammation,... Here are some useful information about Rotaforte to help patients learn and Use medications safely and effectively.
1. What is Rotaforte?
Rotaforte is a drug belonging to the group of anti-parasitic, anti-infective, anti-viral and anti-fungal drugs. Rotaforte is manufactured in the form of film-coated tablets and is packaged in boxes of 2 blisters x 10 film-coated tablets.
Rotaforte drug has the main ingredients Metronidazole, Spiramycin and some other excipients such as: Amidon, Dicalcium phosphate, PVP, Sodium glycolate starch, Talc, Magnesium stearate, HPMC, Titanium dioxide, PEG, Ponceau and Oxyd Red iron is enough for 1 tablet.
2. What are the uses of Rotaforte?
Rotaforte drug is used in the following cases:
Treatment of acute, chronic or recurrent oral infections such as: tooth abscess, inflammation, cellulitis around the jawbone, parotid gland inflammation, periodontitis, gingivitis, periodontitis, stomatitis and inflammation under the jaw... Rotaforte is used to prevent oral infections after surgery.
3. Dosage - How to use the drug Rotaforte
3.1. How to use Rotaforte Drug Rotaforte is prepared in the form of film-coated tablets, used orally, according to tablets.
3.2. Dosage The dose of Rotaforte drug depends on each subject and the course of the disease, there will be an appropriate dose. Here is the dose of Rotaforte for reference as follows:
For adults: The dose of Rotaforte is 4-6 pills in a day, divided into 2-3 times. For children from 10 years old to 15 years old: The dose is 1 tablet x 3 times/day. For children from 5 years old to 10 years old: Take 1 tablet x 2 times/day.
4. What to do when using an overdose of Rotaforte
In case the patient uses an overdose of Rotaforte, some symptoms will appear such as: Feeling nauseous, vomiting and ataxia. Neurotoxic effects include convulsions, peripheral neuritis. At present, there is no specific antidote, symptomatic treatment and support for the case of overdose of Rotaforte.
5. In which cases should Rotaforte not be used?
Rotaforte drug is not used for patients with hypersensitivity, history of allergy to Metronidazol, Imidazol derivatives or Acetyl Spiramycin along with some other excipients in the drug. Rotaforte is contraindicated for use in women who are breastfeeding. Do not use Rotaforte to treat people with blood clotting disorders. Care should be taken when administering Rotaforte to patients with severe hepatic impairment.
6. Drug interactions of the drug Rotaforte
In Rotaforte contains the ingredient Acetyl Spiramycin, so it should not be used simultaneously with oral contraceptives because it will lose the contraceptive effect. Note that Rotaforte should not be used concurrently with Disulfiram because it will cause neurotoxic effects such as psychosis, confusion. Rotaforte interacts with oral anticoagulants such as Warfarin. Co-administration increases the toxicity of anticoagulants and increases the risk of bleeding by reducing hepatic catabolism. Note, if the patient needs to regularly check the Prothrombin levels in the case of combination use, the dose of anticoagulants must be adjusted. Taking Rotaforte with Vecuronium (a muscle relaxant) will increase the effect of this Vecuronium drug. Rotaforte when used concurrently with Lithium increases the concentration of Lithium in the blood and causes toxicity. Rotaforte will increase the toxicity of Fluorouracil by reducing clearance when co-administered. During treatment with Rotaforte, the patient should not drink alcohol because it will cause the Antabuse effect, which manifests as: body heat, vomiting, vomiting and heart palpitations.
7. What side effects does Rotaforte cause?
During the use of Rotaforte, patients may experience some unwanted side effects such as:
Common:
There are symptoms of gastrointestinal disorders such as: stomach pain, nausea, vomiting vomiting and diarrhea. May cause allergic reactions such as: Hives. Glossitis, stomatitis and a metallic taste in the mouth. Moderate leukopenia. Rarely:
Dizziness, ataxia, loss of coordination. Sensation. Sensory and motor polyneuropathy. Renal-urinary: Urine is reddish brown. Common cases of unwanted effects will recover immediately after taking Rotaforte. In rare cases, prolonged treatment is required. Inform your doctor about other undesirable effects that patients experience while taking Rotaforte.
8. Precautions when using Rotaforte
When using the drug Rotaforte, patients may encounter some of the following attention such as:
Caution must be exercised when used in patients with suspected gastric ulcer disease, ileitis or chronic colitis. Because Rotaforte is prepared in the form of film-coated tablets, it will cause slow release in the body, toxic to the elderly or people with slow intestinal transit. Note that Rotaforte should not be taken while lying down. In pregnant women: Animal studies have shown that metronidazole is not teratogenic and non-toxic to the fetus. Clinical studies on many pregnant women using Metronidazole in the first 3 months of pregnancy, there were no cases of causing malformations to the fetus. Although the component of Spiramycin crosses the placenta, the concentration of the drug in the placental blood is lower than in the mother's blood, so Spiramycin does not cause complications for the pregnant woman. In breast-feeding women: Spiramycin and Metronidazol are both excreted in breast milk, so Rotaforte should be avoided in nursing mothers. Above is all information about Quinacar 5mg, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Note: Rotaforte is prescribed by a doctor or pharmacist, so patients should not self-medicate.
