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Rostor 5 belongs to the group of cardiovascular drugs, used in the treatment of cases of dyslipidemia. Let's learn about drug information Rostor 5 through the article below.1. What are the effects of Rostor 5?
Rostor 5 is prepared in the form of film-coated tablets, with the main ingredient being Rosuvastatin (as Rosuvastatin calcium) with a strength of 5mg. Rosuvastatin has the effect of inhibiting the activity of the enzyme HMG Co-A reductase in the liver, preventing HMG Co-A from converting into mevalonate - a precursor of cholesterol, thereby helping to reduce cholesterol levels produced in the liver. Rosuvastatin lowers levels of LDL-cholesterol (also known as bad cholesterol - the cause of atherosclerotic plaques), total cholesterol, blood triglycerides and increases HDL-cholesterol (also known as good cholesterol - helps reduce cholesterol in tissues and blood vessels, protects the vessel walls).2. What are the uses of Rostor 5?
Rostor 5 is commonly used to treat the following cases:Primary hypercholesterolemia (including heterozygous or homozygous familial hypercholesterolemia) Mixed dyslipidemia (increased cholesterol levels) , blood triglycerides, LDL, VLDL).
3. Dosage - how to take Rostor 5
The dosage of the drug depends on the degree of dyslipidemia, cardiovascular risk as well as the possibility of unwanted effects in each patient.Recommended starting dose is 5mg or 10mg, once a day.
The dose can be adjusted after 4 weeks if needed.
The high dose of 40 mg should only be considered in severely hypercholesterolemic patients at high cardiovascular risk (particularly those with familial hypercholesterolemia), for whom treatment goals are not achieved. 20mg dose and need to closely monitor the disease status in these subjects.
4. Contraindications to the drug Rostor 5
Do not use Rostor 5 in the following cases:People with a history of hypersensitivity to any ingredient in the drug. Advanced liver disease, liver enzyme tests more than 3 times the normal limit. Severe kidney failure. People with muscle diseases (myositis, rhabdomyolysis,...). People who are taking Cyclosporin. Women who are pregnant and breastfeeding.
5. Side effects of the drug Rostor 5
When using Rostor 5 may experience some of the following side effects: when using Rostor 5 may experience some of the following side effects:
Digestive disorders: Nausea, vomiting, abdominal pain, constipation, diarrhea . Nervous disorders: Fatigue, headache, dizziness, dizziness. Skin itching, rash, urticaria. Muscle pain: muscle aches, tendonitis, cramps, in severe cases, myositis, rhabdomyolysis. Acute renal failure due to rhabdomyolysis. Damage to liver cells, increased liver enzymes. Increased blood sugar. In the process of using the drug, if you see any serious abnormal symptoms, you should immediately contact your treating doctor or medical staff for instructions and timely treatment.
6. Interactions with drugs Rostor 5
When using Rostor 5 at the same time can cause interactions with some of the following drugs:Rostor 5 when used with vitamin K anticoagulants (warfarin) may increase the INR value. Co-administration of Rosuvastatin with gastric acid-containing antacids containing aluminum and magnesium hydroxide may reduce plasma concentrations of rosuvastatin, resulting in decreased therapeutic efficacy. Increased muscle toxicity when using Rosuvastatin concomitantly with gemfibrozil, other lipid-lowering drugs, high dose niacin (>1g/day), colchicine.
7. Notes and cautions when using Rostor 5
When using Rostor 5, caution should be exercised in the following cases:Before and during treatment with Rostor 5, patients should combine measures to change a scientific diet, exercise, and exercise control. Treating diseases that can be the cause of hyperlipidemia, helping to increase the effectiveness of disease treatment. Test blood lipid indexes (Cholesterol, Triglyceride, HDL, LDL) periodically to monitor the effectiveness of treatment and adjust the drug dose when necessary. Use with caution in patients with a history of liver disease, renal failure, hypothyroidism, myopathy, alcoholism. Liver function tests should be performed prior to treatment with Rostor 5, with particular caution in patients with symptoms suggestive of impaired liver function such as fatigue, anorexia, weight loss, abdominal pain, jaundice and mucous membranes. , dark urine. Rosuvastatin should not be used when the CK test is more than 5 times the upper limit of normal. However, routine testing of blood CK levels in the absence of clinical symptoms is not recommended. The drug should not be used in patients with severe infections, hypotension, surgery, trauma, electrolyte disturbances, endocrine and metabolic abnormalities, uncontrolled seizures. The drug can cause harm to the fetus and is excreted in breast milk causing serious effects, so it is not recommended for use by pregnant or breastfeeding women. Based on its pharmacological properties, the drug has no influence on the ability to drive or use machines, but the drug can cause dizziness and should be used with caution when this symptom occurs. Above is some information about the use of Rostor 5 medicine, if you need advice or have any questions, please consult a qualified doctor / pharmacist for advice.
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