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Retento 800 is prescribed by doctors mainly for cases of neurological impairment, brain damage or sickle cell anemia,... Before and during the course of treatment. Retento 800 drug, patients need to follow the correct dosage and medication instructions as recommended by the doctor.1. What is Retento 800?
Retento 800 belongs to the group of psychotropic drugs, manufactured by XL Laboratories Pvt., Ltd - India. Retento 800 drug is used to treat peripheral and central brain disorders, decline in nerve function, cognitive function,...
Retento 800 drug is prepared in the form of film-coated tablets, Packed in boxes of 10 blisters x 10 tablets. Each Retento tablet contains the main ingredient Piracetam (800mg content) and other excipients just enough.
The main active ingredient Piracetam in the drug is a substance that brings a euphoric effect, helping to improve the metabolism of nerve cells. Piracetam can affect a number of neurotransmitters, such as Dopamine, Noradrenaline and Acetylcholine. In addition, the active ingredient Piracetam of Retento 800 also significantly improves the metabolic environment, helping nerve cells work more efficiently.
According to research, Piracetam has the ability to protect against ischemic metabolic disorders through the mechanism of enhancing the brain's resistance to oxygen deprivation to the brain. Moreover, Piracetam also has the effect of increasing the mobilization and utilization of Glucose without having to depend on the oxygen supply, thereby facilitating the Pentose pathway, while helping to maintain the synthesis process. brain energy. Not only that, the active ingredient Piracetam also helps promote the release of Dopamine, bringing positive effects to memory formation. On the other hand, Piracetam in Retento 800 has the ability to reduce platelet aggregation and restore the ability to deform and pass through the capillaries of red blood cells. The anti-vibration effect of Retento 800 was also noted by the study.
2. Retento 800 uses and contraindications
2.1. Indications for use of the drug Retento 800 Retento 800 is indicated for use in the following cases:
Treatment of symptoms caused by dizziness. Treatment of certain brain damage caused by traumatic brain injury or after brain surgery, including cerebral hematoma, mental disorders, ischemia, hemiplegia. Treatment of a number of central nervous system disorders, including headache, dizziness, alcoholic delirium, disturbances of consciousness. Treatment of attention deficit, learning difficulties in children, memory impairment or dementia in the elderly. Treatment of sickle cell anemia or acute ischemia. Treatment of chronic alcoholism or myoclonic symptoms of cortical origin. 2.2. Contraindications to the use of Retento 800 Do not use Retento 800 for the following cases:
Patients with a history of allergy or hypersensitivity to the active ingredient Piracetam or any other ingredient in the drug. Retento 800 is contraindicated in patients with severe renal impairment and creatinine clearance < 20ml/min. Do not use Retento 800 for people with liver failure or Huntington's disease.
3. Dosage and how to use Retento 800
3.1. Dosage of Retento 800 The following is information about the recommended dosage of Retento 800 specifically for each patient:
The usual dose of Retento 800 is from 30 to 160mg / kg / day, depending on the indications. doctor's decision. Patients can divide the dose of the drug about 2-4 times / day. Long-term treatment dose for the elderly with psychosomatic syndrome: Take from 1.2 to 2.4g / day. The maximum dose can be up to 4.8g/day during the first weeks of treatment. Dose to treat cognitive impairment after traumatic brain injury (with/without dizziness): Take the initial dose from 9-12g/day, maintain the dose of 2.4g/day and take it for a minimum of 3 weeks. Dose to treat alcoholism: Take 12g/day in the first episode of alcohol withdrawal, then maintain 2.4g/day. Treatment dose for sickle cell anemia: Oral 160mg/day, divided dose into 4 times/day. Dosage for treatment of myoclonic tremor: Take 7.2g/day, divided into 2-3 times/day. Depending on the patient's response, increase 4.8 g/day every 3 to 4 days until a maximum dose of 20 g/day is reached. 3.2. Instructions for proper and effective use of the drug Retento 800 Retento 800 medicine is in the form of tablets, so the drug will be taken orally. Patients can take the drug with cooled boiled or filtered water to ensure optimal drug quality.
Avoid taking Retento 800 with alcoholic beverages, carbonated water or other drinks containing stimulants. These beverages may affect the absorption and effectiveness of Retento 800.
4. Possible side effects when using Retento 800
During the use of Retento 800, patients may experience some unwanted side effects, including:
Common side effects (ADR 1/100): Fatigue (systemic), nausea , vomiting, abdominal pain, diarrhea, abdominal distention, restlessness, headache, excitability, drowsiness or insomnia. Uncommon side effects (1/1000 < ADR < 1/100): Dizziness (generalized), sexual arousal or tremor. When noticing any side effects, patients need to contact a doctor or go to a medical facility immediately for treatment. Some reactions can have serious health risks if not detected and corrected early.
5. Important notes when using Retento 800
5.1. What precautions should be taken while using Retento 800? Since the active substance Piracetam is eliminated primarily by the kidneys, the increase in the half-life of the drug is directly related to the creatinine clearance and the degree of renal impairment. As recommended by experts, people with kidney failure need to be careful when using Retento 800 and pay attention to always monitor kidney function in these subjects, especially elderly patients.
Specifically, when the creatinine clearance is < 60ml/min or the serum creatinine level is > 1.25mg/100ml, the dose of Retento 800 for the patient will be considered adjusted as follows:
Creatinine clearance from 60 – 40ml/min and serum creatinine from 1.25 – 1.7mg/100ml: Only half of the normal dose should be taken. Creatinine clearance from 40 - 20ml / min and serum creatinine from 1.7 - 3mg / 100ml: Take 1/4 of the normal dose. The use of Retento 800 during pregnancy can lead to adverse effects on the fetus, such as an increased risk of birth defects, birth defects or miscarriage. This is especially the case if you take Retento 800 during the first 3 months of pregnancy. Therefore, pregnant women are recommended by doctors not to be treated with Retento 800 during this period. If it is necessary to take medicine, the patient should carefully consult and consult with a specialist doctor / pharmacist before making a decision.
Research also shows that Retento 800 can be passed on to infants through breast milk. Therefore, women who are breastfeeding should limit or avoid taking Retento 800 during this period. If medication is required, the patient also needs to talk to the doctor about the benefits and harms that the drug can bring to make the right decision.
5.2. Interactions of Retento 800 with other drugs When concomitantly combining Retento 800 with one or more other drugs may lead to interactions, including synergistic or antagonistic. The following are drugs that may interact with Retento 800:
Patients are at increased risk of confusion, sleep disturbances or nervous irritability when Retento 800 is used in combination with Retento 800. T3 and T4 thyroid extracts. In some patients, when the prothrombin time has been stabilized with Warfarin, the prothrombin time may be increased again when used with Retento 800. During Retento 800, the patient can still continue to apply the method. classic treatment for alcoholism, such as tranquilizers or vitamins if the body is agitated or deficient in vitamins. The article has provided information on what Retento 800 is, dosage and precautions for use. To ensure safety for health and maximize the effectiveness of treatment, you need to use Retento 800 t pig exactly as directed by your doctor.
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