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Prindax drug has the main ingredient Metformin hydrochloride and other excipients. Prindax is used to lower high blood sugar levels in people with diabetes.
1. What is Prindax?
Prindax drug belongs to the group of hormones, hormones. Prindax is prepared in the form of film-coated tablets and packaged in boxes of 3 blisters x 10 tablets.
Prindax medicine has the main ingredient Metformin hydrochloride with the content of 850mg and other excipients in the drug.
2. What is the use of Prindax?
Metformin lowers elevated blood sugar levels in people with diabetes, but has no noticeable hypoglycemic effect in people without diabetes. Metformin has a number of theories explaining the mode of action, specifically:
Inhibition of intestinal glucose absorption. Increased use of glucose in cells. Inhibits gluconeogenesis in the liver. Metformin hydrochloride is a hypoglycemic biguanide used for the treatment of non-insulin dependent diabetes when blood glucose cannot be controlled with diet alone.
Metformin may be prescribed in patients who no longer respond to sulfonylureas in addition to the sulfonylurea derivative being used. In obese patients Metformin can induce beneficial weight loss, which is sometimes the rationale for the combination of metformin and insulin in insulin-dependent diabetes.
3. Dosage - how to take Prindax
Prindax is used by mouth with food or milk to minimize stomach upset.
Non-insulin dependent diabetes: The starting dose should be 500mg Metformin per day.
If blood sugar is not controlled, the dose can be gradually increased to a maximum of 5 500mg Metformin tablets or 3 850mg Metformin tablets per day, divided into 2 to 3 doses.
4. Contraindications to the use of Prindax
Prindax is not used in the following cases:
Patients with impaired kidney function, impaired liver function. Thyroid disease Heart failure Pregnant women Respiratory failure.
5. Be careful when using Prindax for treatment
Prindax should not be used in patients with heart failure, dehydration, acute or chronic alcoholism, patients with any condition that could lead to lactic acidosis.
Prindax should not be used in pregnant and lactating women.
6. Prindax drug interactions
There have been reports that the use of metformin with alcohol in large doses has been reported to increase the risk of lactic acidosis.
In addition, to prevent hypoglycemic events, patients should gradually increase the dose of metformin as well as the sulfonylurea in patients receiving combination therapy.
7. What side effects does Prindax cause?
During the use of Prindax, patients may experience some unwanted side effects such as:
Increased lactic acid causing acidosis, nausea, metallic taste in the mouth, Gastrointestinal disorders: Abdominal pain , abdominal distension with diarrhea. This condition can be significantly reduced by taking metformin after meals and increasing the dose gradually. Vitamin B12 deficiency has been reported but is very rare. Prolonged use of Prindax causes anorexia, bitter mouth and weight loss. Patients should inform their doctor or pharmacist of any side effects they experience while taking Prindax.
8. What should I do with an overdose of Prindax?
In case of overdose Prindax will lead to lactic acidosis. Prindax should be discontinued and the acidosis corrected by intravenous injection of 7.5% sodium bicarbonate solution. In patients with severe acidosis, peritoneal dialysis or hemodialysis should be performed.
Note: Prindax is prescribed by a doctor or pharmacist, patients do not arbitrarily use Prindax.
