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Pirolam drug is often used in the treatment of a number of diseases such as scalp fungus, foot fungus, nail fungus, ... So what is the use of Pirolam and how is it used?1. Uses of Pirolam
Pirolam is produced in the form of a topical cream, the main ingredient in each tube is Ciclopirox 10mg. Ciclopirox is a broad-spectrum synthetic antifungal agent. Ciclopirox is effective against both fungi and fungal spores. This effect is attributed to its ability to inhibit uptake (leucin) and prevent the accumulation of substrates in fungal cells that are important in fungal cell growth and metabolism, including inhibition of the calcium and potassium ions into fungal cells.Ciclopirox also forms chelate complexes with multivalent cations (Fe3+, AI3+) and inhibits the activity of some metal-dependent active enzymes, which are involved in fungal cell respiration.
Ciclopirox has a stronger anti-inflammatory effect and better penetration into the keratin layer. The spectrum of action of Ciclopirox includes dermatophytes, yeasts, molds and mixed fungi.
The anti-inflammatory effect of Ciclopirox is due to its ability to inhibit cyclooxygenase and lipoxygenase, which is stronger than ketoconazole, fluconazole, miconazole and naphtyllin.
In addition, Ciclopirox also has effects on Gram-positive, Gram-negative bacteria and inhibits Trichomonas, Mycoplasma, Chlamydia independent of pH.
Pirolam is indicated in the following cases:
Treatment of fungal skin diseases such as tinea capitis, tinea pedis, onychomycosis and tinea pedis caused by: Trichophyton rubrum Trichophyton mentagrophytes Epidermophyton floccosum Microsporum canis Microsporum gypseum Candida albicans Candida tropicalis Candida krusei Candida parapsilosis Cryptococcus neoformans Aspergillus fumigatus Infectious conditions caused by Gram-positive and Gram-negative bacteria, as well as mycoplasma. Pirolam is contraindicated in the following cases:
People with hypersensitivity to Ciclopirox or any of the excipients of the drug. Do not give the medicine to children under 6 years old. Because there are currently no adequate studies evaluating the safety of ciclopirox in children. Do not use Pirolam for fungus in the eye or the tissues around the eye. Use caution when using Pirolam in the following cases:
Pregnant women and lactating women: Use Pirolam only in necessary cases and do not scratch the itch and scratch the lesions caused by pruritus. mushroom. Avoid contact of Pirolam with eyes. Do not use Pirolam vaginally. Avoid wearing clothing and shoes that are impervious to moisture and heat in the affected area. After washing or bathing, the infected areas should be thoroughly dried before applying the medication. Every day, it is necessary to change clothes, towels, bandages in direct contact with infected areas. Wash clothes and towels at 90°C. Pirolam contains propylene alcohol which may cause skin irritation. Pirolam medicine contains methyl parahydroxybenzoate, propyl parahydroxybenzoate which can cause delayed skin allergies and sometimes cause bronchospasm.
2. Dosage and how to use Pirolam cream
Pirolam is a medicine for external use. Dosage should be in accordance with the doctor's instructions, the recommended dose is as follows:Apply Pirolam 2 times a day to the infected skin, gently rub or let the gel dry naturally. Continue using the medicine until the symptoms are gone. The optimal duration of treatment with Pirolam is up to 3 weeks.
In order to prevent recurrence, you should continue treatment for 10 days after the lesions have recovered. Inform your doctor if your condition does not improve after 4 weeks.
Do not use cloths or patches on the infected area, except to treat nail fungus, which can be covered with a bandage on the infected area.
3. Pirolam side effects
When using Pirolam topical cream, you may experience unwanted effects. Side effects include: Burning, skin irritation, pruritus, erythema and edema observed in some patients (1-4%). Inform your doctor about the side effects you experience while using Pirolam.4. Pirolam drug interactions with other drugs
There were no interactions when Pirolam was applied concurrently with 1% hydrocortisone cream.Pirolam has a synergistic effect with itraconazole or terbinafine, so it is necessary to reduce the dose of drugs when used simultaneously.
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