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Pectomucil 20mg drug with the active ingredient isotretinoin is used to treat severe acne and does not respond to treatment when done by other conventional methods. So how should Pectomucil 20mg be used?
1. Uses of Pectomucil 20mg
Pectomucil 20mg has some indications in the treatment as follows:
Patients with severe acne and unresponsive to other conventional treatments. Consequences cause many bad scars and facial disfigurement. Cases of long-term acne have been treated with many methods but not helped.
2. Pharmacodynamics of the drug Pectomucil
The active ingredient Isotretinoin contained in the drug Pectomucil is a stereoisomer of tretinoin in the group of vitamin A derivatives that have anti-acne effects. To date, the mechanism of action of isotretinoin has not been elucidated. However, according to some studies, isotretinoin inhibits the activity of the sebaceous glands to reduce sebum production and reduce the size of this gland. On the other hand, isotretinoin also helps improve the immune system and reduces inflammation by acting on monocytes.3. How to use Pectomucil
Pectomucil is used orally and taken with meals.
For adults, usually start with a dose of 0.5 - 1mg/kg/day, taken twice a day. Use up to 2mg/kg/day. In the case of children over 12 years old can be used from 0.5 to 1mg/kg/day, divided into 2 times (used when very severe acne).
It should be noted that the above dosage is only the recommended dose for reference. Depending on the patient's condition and medical condition, the specialist doctor will make a reasonable prescription.
4. Some notes when using Pectomucil
Pectomucil contains the active ingredient Isotretinoin which is a derivative of vitamin A, so an overdose can cause poisoning due to excess vitamin A. Typical symptoms of vitamin A poisoning include: Itching, discomfort, irritation skin, stomach pain, severe headache, cracked lips, nausea and vomiting. Then it should be handled by:
Stop using the drug immediately. Immediately contact the nearest medical facility for timely emergency treatment. Gastric lavage is the best method to reduce drug absorption and should preferably be performed within the first 2 hours after poisoning. Pectomucil 20mg has some contraindications such as:
Patients with a history of hypersensitivity to any ingredient in the drug. Patients with kidney failure, liver failure, vitamin A poisoning. Use in combination with Tetracycline. Women who are pregnant and lactating or women who are planning to become pregnant. Care should be taken when using the drug in the following cases:
The drug has a teratogenic risk. Therefore, patients need to apply contraceptive measures while using the drug. You should see your doctor to be sure you are pregnant during and after treatment with isotretinoin. Patients should not donate blood during and after 1 month of discontinuing use because isotretinoin can be dangerous to the pregnant woman receiving blood. At the beginning of treatment, acne may increase a lot, but after 7-10 days, it will gradually decrease. Avoid exposure to direct sunlight or UV rays and use sunscreen when going outside. Do not treat the skin with laser or other corrosive chemicals after 5-6 months of isotretinoin treatment, as it may result in keloid scars or hyperpigmentation on the treated area. Topical agents that have a descaling and keratinolytic effect should not be used with isotretinoin, as this may cause increased skin irritation. Additional creams or ointments should be used to keep the skin, lips and eyes moist from the start of isotretinoin treatment, as isotretinoin often dries out the skin and lips. Wear glasses instead of contact lenses. Liver enzyme levels should be checked periodically before taking the drug, 1 month after and every 3 months during treatment. If liver enzyme values increase and are accompanied by other symptoms, the dose should be reduced or discontinued. When symptoms are severe, the drug should be discontinued because the patient may be suffering from hereditary fructose intolerance. The drug has some side effects on the nervous system, hearing and vision, so patients need to be careful when operating machinery or driving. Isotretinoin should not be used by pregnant or nursing women. Above are important information about Pectomucil 20mg that you need to pay attention to in order for the drug to be highly effective in treatment.
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