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Paxicox 100 belongs to the group of anti-inflammatory and analgesic drugs with the main active ingredient being Celecoxib 100mg. Knowing enough information about ingredients and uses helps patients to use the drug effectively.
1. What are the uses of Paxicox 100?
1.1. What is Paxicox 100mg? Paxicox 100 belongs to the group of anti-inflammatory and pain relievers including the following ingredients:
Main active ingredient: Celecoxib 100mg. Excipients: Lactose, Sodium starch glycolate, Polyvinyl pyrrolidone PVP K30, sodium lauryl sulfate, magnesium stearate, corn starch. The drug is prepared in the form of 100mg tablets, blisters of 10 tablets, boxes of 3 blisters or 10 blisters. The drug Paxicox 100mg is recommended for use in adults.
1.2. What does Paxicox 100 do? Paxicox 100mg is a non-steroidal anti-inflammatory drug (NSAID) used to treat arthritis. With the effect of reducing inflammation and reducing swelling, redness, pain, and accompanying pain. Paxicox 100mg differs from other NSAIDs in that it is less likely to cause peptic ulcers (at least for short-term treatment) and does not interfere with blood clotting.
Paxicox 100 is prescribed by doctors in the following cases:
Symptomatic treatment of osteoarthritis in adults. Symptomatic treatment of rheumatoid arthritis in adults. Adjuvant therapy to reduce polyp count in conventional therapy for familial adenomatous polyposis. Treatment of acute pain, including pain after surgery, tooth extraction. Treatment of primary dysmenorrhea.
2. Usage of Paxicox 100
2.1. How to take the medicine Paxicox 100 The drug Paxicox 100 is made in the form of convenient tablets for oral administration. The patient should take the medicine with a sufficient amount of filtered water, should be taken during or after a meal
Patients should pay attention not to break, chew, crush but drink the whole pill. Do not mix the medicine with any other mixture, take it as directed by doctor
2.2. Dosage of the drug Paxicox 100 To treat osteoarthritis - joints, the dose must be adjusted according to the needs and response of each patient. Accordingly, look for the lowest effective dose. Reference dosage is as follows:
Osteoarthritis - joint: usual dose: 200mg/day orally or divided into 2 equal doses. Doses higher than 200 mg/day (eg, 200 mg/dose, twice daily) were not more effective. Rheumatoid arthritis in adults: usual dose: 100-200mg/time orally 2 times a day, higher dose (400mg x 2 times/day) has no better effect than dose of 100-200mg x 2 times/day. Colon - rectal polyps: 400mg/time, 2 times a day. According to the manufacturer, the safety and effectiveness of therapy over 6 months have not been studied. Pain and Dysmenorrhea: The usual dose in adults is 400mg orally once, followed by 200mg if needed on the first day. For continued pain relief, a dose of 200mg orally twice a day may be given, if needed. Elderly: No dose adjustment is required, although plasma concentrations are increased. However, for the elderly with a body weight of less than 50 kg, the lowest recommended dose must be used at the start of treatment. Renal impairment: Currently there are no studies and not recommended for people with severe renal impairment. The manufacturer has no special recommendations for dose adjustment in patients with chronic renal failure. Hepatic impairment: Not studied. According to the manufacturer, should not be used in patients with severe liver failure. For moderate hepatic impairment, the manufacturer recommends a dose reduction of approximately 50%. Handling missed dose: Usually, the medicine can be taken within 1-2 hours compared to the prescribed in the prescription. Unless there is a strict rule on how long to use it, it can be taken a few hours after forgetting. However, if the time is too far from the time you need to drink, you should not make up for it, because it can be dangerous to the body. Patients need to strictly follow or consult a doctor before making a decision. Treatment of overdose: Symptoms of possible overdose are coma, nausea, vomiting and epigastric pain, gastrointestinal bleeding. Rarely, hypertension, acute renal failure, respiratory failure have occurred. Overdose treatment: Only symptomatic treatment and supportive treatment in overdose. If symptoms of overdose appear within 4 hours of taking the drug, the patient may be required to induce vomiting or use activated charcoal or use an osmotic enema.
3. Contraindications of the drug Paxicox 100
Patients who are allergic to the main active ingredient Celecoxib or any of the excipients listed above in Paxicox 100 Patients with a history of allergy to sulphonamides, aspirin or other nonsteroidal anti-inflammatory drugs . Patients with asthma, urticaria or allergies when taking the drugs. Treatment of pain during coronary artery bypass graft (CABG) surgery. Inflammatory bowel disease (Crohn's disease, ulcerative colitis). Severe heart failure. Severe renal impairment (creatinine clearance less than 30 ml/min). Severe liver failure.
4. Note when using Paxicox 100
Note when using Paxicox 100 as follows:
Do not arbitrarily reduce the dose, increase the dose or stop using Paxicox 100 while in treatment. Check the expiry date of Paxicox 100 on the package before using the medicine, do not use the medicine that has shown signs of mold or the packaging is open. Do not give Paxicox 100 to children or keep it within the reach of children. The subjects to note before taking Paxicox 100: children under 15 years old, the elderly, pregnant women, lactating women, people with liver failure, kidney failure... Or people with myasthenia gravis, peptic ulcer, hepatic coma. Pregnancy: There are currently no controlled data on the safety of Paxicox 100 in pregnant women. Therefore, only use the drug when the benefits outweigh the risks. In particular, it is necessary to consult a doctor before use. Use with caution in patients with a history of heart disease, hypertension, left ventricular dysfunction, edema, signs of liver dysfunction, or liver abnormalities. Caution should be exercised when using the drug when driving and operating machinery or requiring high concentration, as the drug may cause dizziness. Celecoxib interacts with drugs: drugs that inhibit cytochrome P450 2C9 enzymes, Diuretics, Aspirin, Fluconazole, Lithium, Warfarin should be used with caution. It is better to tell your doctor about all the medications you are taking and your medical history to balance the dosage accordingly.
5. Side effects of the drug Paxicox 100
During the use of Paxicox 100, patients may experience some of the following side effects:
Diarrhea, flatulence, nausea, excessive fatigue, lack of energy, loss of appetite. Sore throat, cold symptoms, flu-like symptoms, fever, Unexplained weight gain Unusual bleeding or bruising, itching. pain in the upper right part of the stomach Yellow skin or eyes, blisters, rash, hives Swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles or legs Hoarseness, trouble swallowing or difficulty breathing, pale skin, fast heartbeat Cloudy, discolored or bloody urine, back pain, difficult or painful urination, frequent urination, especially at night. Usually, side effects or unwanted effects, unwanted effects will go away when the drug is stopped. However, if there are rare side effects that are not mentioned in the leaflet, the patient should immediately inform the doctor or medical person if there is any doubt about the side effects of Paxicox 100.
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6. How to store Paxicox 100
The shelf life of the drug is 36 months from the date of manufacture. Store Paxicox 100 in a dry, cool, clean place, in the original packaging to limit bacterial contamination. Do not keep the medicine in the refrigerator, the best storage conditions are between 25 - 30 degrees Celsius. Do not expose the medicine to direct sunlight. Keep out of reach of children and pets. Paxicox 100 belongs to the group of anti-inflammatory and analgesic drugs with the main active ingredient being Celecoxib 100mg. To ensure the effectiveness of treatment and avoid unwanted side effects, patients need to strictly follow the instructions of the doctor, professional pharmacist.
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