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Opevalsart 40 is used to treat hypertension, heart failure grade II - IV. To ensure the effective treatment of the drug and avoid unwanted side effects, patients need to use Opevalsart 40 as prescribed by the doctor / pharmacist.
1. What is Opevalsart?
Opevalsart is prepared in the form of film-coated tablets, packing specifications: Box of 3 blisters x 10 tablets. The ingredient Valsartan 40mg in Opevalsart acts selectively on the AT1 receptor subtype, which controls the action of angiotensin II. An increase in serum angiotensin II concentrations when the AT1 receptor is inhibited by valsartan leads to the activation of the AT2 receptor, which has a balancing effect with the AT1 receptor.
2. Indications for taking Opevalsart 40
Opevalsart 40 is indicated in the treatment of the following conditions:
Treatment of hypertension. Treatment of heart failure grade II - IV in patients with conventional therapy with diuretics, inotropes as well as ACE inhibitors or beta blockers.
3. Dosage, how to use Opevalsart 40
Dosage for treatment of high blood pressure:
The recommended dose is 80mg once a day. The therapeutic effect of Opevalsart 40 will be evident within 2 weeks and reach a maximum after 4 weeks. For patients whose blood pressure is not adequately controlled, the daily dose may be increased to 160 mg or with additional diuretics. No dose adjustment is required for patients with renal/hepatic impairment not of biliary origin and without cholestasis. Opevalsart 40 can also be used with other antihypertensive agents. Dosage for heart failure:
The recommended initial dose is 40mg twice a day. The highest dose of Opevalsart is 80mg - 160mg twice daily, in tolerable patients. The dose of Opevalsart should be reduced when used in combination with anti-diuretics. The maximum daily dose of Opevalsart is 320mg but must be divided into doses. The safety and effectiveness of Opevalsart have not been established in children.
Dosage of Opevalsart 40 above is for reference only. The specific dose of Opevalsart 40 will depend on the condition and the progression of the disease. To get the right dose of Opevalsart 40, patients need to consult their doctor/pharmacist.
4. Contraindications to taking Opevalsart 40
Opevalsart 40 should not be used in the following cases:
Hypersensitivity to the drug ingredient Opevalsart 40; Pregnant and lactating women; Lower blood pressure; Functional aortic stenosis; Renal artery stenosis ; Lesions that cause renal artery stenosis;
5. Use Opevalsart 40 . with caution
Use Opevalsart 40 with caution in the following cases:
People with kidney failure, salt loss and/or fluid loss; Renal artery stenosis; Liver failure; Heart failure ; Drivers and machine operators.
6. Drug interactions
Concurrent use of Opevalsart 40 with the following drugs may increase the interaction:
Cimetidine; Warfarin ; Furosemide; Digoxin; Atenolol; Indomethacin; Glibenclamide. Potassium-sparing diuretics such as Spironolactone, Triamterene, Amiloride; Potassium supplements; Salt substitutes contain potassium. To avoid unwanted interactions when using Opevalsart 40, patients should inform their doctor/pharmacist of all medicines, dietary supplements and herbs... they are taking.
7. Side effects of the drug Opevalsart 40
Opevalsart 40 can cause some of the following side effects for patients:
Headache; Dizzy; Viral infection; Upper respiratory tract infections; Cough, diarrhea; Tired; Rhinitis; Sinusitis ; Backache; Stomachache; Nausea; Sore throat; Athritis. Other side effects include:
Edema, weakness; Insomnia ; Rash; Physiological weakness; Dizzy. During the course of treatment, if there are any unusual symptoms suspected of using Opevalsart 40, you need to notify your treating doctor for timely treatment.
Above is important information about the drug Opevalsart 40, patients should carefully read the instructions for use and use according to the dose prescribed by the doctor to achieve the best effect.
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