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Omefort 20 is used in the treatment of gastroesophageal reflux syndrome, gastrointestinal ulcers and Zollinger-Ellison syndrome. To take the medicine safely and effectively, you should take the tablet whole without crushing or chewing it.
1. What is Omefort 20?
Omefort belongs to the group of gastrointestinal drugs, contains the main ingredient Omeprazol 20mg and is made in the form of hard capsules. Packing: 1 box of 3 blisters x 10 tablets; box of 10 blisters x 10 tablets; bottle of 100 tablets.
2. Uses of Omefort 20
Omefort 20 is used in the treatment of the following diseases:
Treatment of gastroesophageal reflux disease; Treatment of gastrointestinal ulcers; Treatment of Zollinger-Ellison syndrome. Omefort 20 is not contraindicated in people with hypersensitivity to the active ingredient Omeprazole, Esomeprazole, other Benzimidazole derivatives or to any of the ingredients.
3. Dosage and how to use Omefort 20
You should take Omefort 20 tablets whole, do not crush or chew.
Dosage of Omefort 20 for symptomatic relief of acid indigestion:
Take 10 or 20 mg/day for 2-4 weeks. Treatment of gastroesophageal reflux syndrome:
Usual dose: Oral dose of 20 mg x 1 time / day for 4 weeks, if not cured, take another 4-8 weeks. In the case of patients with persistent esophagitis, a dose of 40 mg/day can be taken; The maintenance dose after recovering from acid reflux is 10 mg / day and esophagitis is 20 mg x 1 time / day. Treatment of peptic ulcers:
Single dose: 20 mg/day or 40 mg/day in severe cases. Continue treatment for an additional 4 weeks for duodenal ulcers and 8 weeks for gastric ulcers. Maintenance dose: 10-20 mg x 1 time/day. Eradicating Helicobacter pylori in peptic ulcers:
In combination with other antibiotics in dual or triple therapy. Dual dose Omeprazole 20 mg twice daily for 2 weeks; Triple therapy Omeprazole 20 mg twice daily for 1 week. Treatment of gastric ulcers caused by the use of non-steroidal anti-inflammatory drugs:
Use a dose of 20 mg/day. Treatment of Zollinger-Ellison syndrome:
Oral dose of 60 mg x 1 time / day, adjusted as necessary. The majority of patients will be effectively controlled at doses between 20-120 mg/day, but in some cases doses up to 120 mg 3 times/day can also be used. For daily doses above 80 mg should be divided into 2 times. Prevention of acid aspiration during general anaesthesia:
40 mg dose in the evening before surgery and 2-6 hours before the procedure, an additional dose of 40 mg in patients with impaired renal function:
No need The dose of Omefort 20 must be adjusted in patients with impaired renal function. Dosage of Omefort 20 in patients with liver failure:
Oral dose of 10-20 mg/day. Elderly people > 65 years:
No dose adjustment of Omefort 20 is required in the elderly.
4. Side effects of Omefort 20
Common side effects:
Headache, drowsiness and dizziness. Nausea or vomiting, abdominal pain, gastrointestinal disturbances. Rare side effects when using Omefort 20:
Insomnia, dizziness, fatigue, confusion; Urticaria, rash; Reversible increase in transaminases. Rare side effects when taking Omefort 20:
Sweating, peripheral edema and pulse, fever, anaphylaxis; Decrease in white blood cells and platelets, decrease in whole blood cells, agranulocytosis; Confusion, hallucinations, agitation, depression, hearing disturbances; Gynecomastia in men. Gastritis; Candida infection, dry mouth. Yellow or non-jaundice hepatitis, hepatic encephalopathy; Bronchospasm ; Joint and muscle pain; Interstitial nephritis.
5. Note when using Omefort 20mg
If the patient has symptoms such as weight loss, persistent vomiting, difficulty swallowing, suspected or ongoing gastric ulcer, the possibility of malignancy should be excluded; The use of Omefort in combination with a proton pump inhibitor (PPI) and Atazanavir is not recommended. If coadministration is necessary, close clinical monitoring is required; Omefort may decrease the absorption of vitamin B12. Therefore, the use of Omefort should be considered in patients with reduced stores or at risk of reduced vitamin B12 absorption if treated for a long time; Severe hypomagnesaemia has been reported in patients treated with proton pump inhibitors for at least 3 months and in most cases for about 1 year. Symptoms of severe hypomagnesaemia include fatigue, convulsions and muscle spasticity, delirium, dizziness, and ventricular arrhythmias. This condition should improve after magnesium supplementation and discontinuation of proton pump inhibitors; For pregnant women, in experimental studies, Omefort did not show the ability to cause malformations and toxicity to the fetus. However, to ensure safety, Omefort should not be used by pregnant women, especially during the first 3 months of pregnancy. The use of Omefort in breast-feeding is not recommended. Because the drug has the ability to enter the milk ducts and cause toxicity to the nursing infant. Omefort may cause side effects such as dizziness and visual disturbances. Therefore, it is best not to drive or operate machinery after using the drug. In summary, the use of Omefort 20 is to treat gastroesophageal reflux syndrome, gastrointestinal ulcers and Zollinger-Ellison syndrome. To use Omefort safely and effectively, patients should take it as directed by their doctor or pharmacist.
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