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Nystatin 500,000 IU is a name that appears quite a lot in today's prescriptions. So what is Nystatin 500,000 iu? How to use Nystatin 500,000 and what to pay attention to?
1. What is Nystatin 500,000 iu?
Nystatin 500,000 IU is a drug belonging to the group of drugs used to treat parasites, antifungals, and infections caused by fungal infections. The drug is on the list of prescription drugs.
The drug contains the main ingredient Nystatin 500,000 IU.
Talking about Nystatin, it can be said that this is an antifungal antibiotic that has the ability to inhibit or kill fungi very effectively. The effect of the drug is determined by the concentration factor as well as the susceptibility of the fungus. Nystatin is extracted directly from the culture of Streptomyces Noursei fungus, yellow color, after extracting exists in powder form, slightly soluble in water.
Although considered an antibiotic against fungi, Nystatin drug has no effect on normal bacteria that are mainly sensitive to yeasts, especially Candida.
Nystatin has good antifungal activity thanks to the mechanism of action on sterols that change the permeability of fungal cell membranes. Several studies have concluded that Nystatin is effective against gastrointestinal candidiasis in patients receiving antibiotic therapy. The drug does not cause resistance like conventional antibiotics.
Nystatin is poorly absorbed from the gastrointestinal tract.
2. Uses of the drug Nystatin 500,000 iu
Nystatin drug is mainly used for the prevention and treatment of Candida infections in the gastrointestinal mucosa.
The drug is prepared in the form of sugar coated tablets, smooth and uniform surface. Packing forms:
Box of 2 blisters, each blister of 8 tablets. Box of 10 blisters x 8 tablets. Bottle of 100 tablets. Bottle of 500 tablets. Indications for use:
Treatment and prevention of gastrointestinal candidiasis such as pharyngitis, stomatitis, thrush... or candida disease in the intestines, stomach, esophagus. Vaginitis caused by Candida fungus. Contraindicated to use Nystatin 500,000 IU with:
People with a history of hypersensitivity to any component of the drug. Patients with diabetes because the drug contains lactose, sugar. Nystatin is a drug indicated for treatment of all ages, however, at a concentration of 500,000 IU, it is recommended to be used for fungal infections in adults, not for children and infants. Dosage: Depending on the medical condition, the degree of fungal infection and the clinical symptoms so that the treating doctor can give a reasonable dosage for the patient. Example:
People with esophageal candidiasis but no antibiotic use factor: indicated to take 500,000 to 1000,000 IU/time (1 to 2 tablets/time), 3 to 4 times a day as prescribed. doctor. Prevention of Candida infections in patients being treated with antibiotics: 1,000,000 IU/day.
3. Note when using Nystatin 500,000 VND
Basically, Nystatin is almost non-toxic, does not cause allergies or sensitization, allergies. Some undesirable effects are less common in subjects treated with Nystatin medicine 500,000 IU such as:
Digestive disorders causing nausea, vomiting, and diarrhea. The higher the dose, the greater the risk of side effects. May appear rash, urticaria. Rarely, patients have Steven-Johnson syndrome. To be safe when using Nystatin 500,000 IU, patients need to pay attention to the following basic things:
Use the drug exactly as prescribed by the doctor, do not arbitrarily increase the dose or decrease the dose without consulting the treating doctor. As mentioned above, the drug Nystatin 500,000 IU should only be used to treat adults, not children, infants and young children. When children need to be treated with Nystatin such as thrush ... it is necessary to consult a doctor for a treatment drug with appropriate dosage levels as well as dosage forms. Discontinue the drug as soon as signs of hypersensitivity reactions or other serious side effects appear. Because the drug is poorly absorbed from the gastrointestinal tract, Nystatin 500,000 IU is not indicated in patients with systemic fungal infections. For pregnant and lactating women, caution should be exercised when taking the drug, and should consult a doctor before taking it. Riboflavin phosphate has the ability to cancel the antifungal effect of Nystatin, so it should be avoided. In addition, drugs that cover the digestive mucosa and change intestinal motility also affect the effect of the drug. If you miss a dose, take it as soon as you remember, skip the dose if it's almost time for the next dose. Especially do not take a double dose to make up for the missed dose. In case of overdose of Nystatin, closely monitor the clinical symptoms of the patient. Also contact the nearest specialist or medical facility for timely support. Go to the hospital immediately if you feel severe symptoms. Currently, there is no specific treatment for toxicity caused by Nystatin overdose. Clinical treatment is mainly symptomatic treatment, carrying out intestinal lavage and the use of bleach. Store medications according to the manufacturer's instructions. In general, Nystatin is a very effective antifungal, anti-fungal, with few side effects. However, the use of the drug still requires the prescription and guidance of a specialist. Contact your doctor if you or a loved one is showing signs of a fungal infection for advice on the best treatment.
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