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Nimotop belongs to the group of calcium channel blockers containing the active ingredient nimodipine. The drug is used in the prevention and treatment of vasospasm, causing ischemic neuropathy, neurological disorders,... This is a prescription drug, so the patient needs to follow the instructions of the doctor. doctor while taking the drug.
1. Uses of Nimotop
What is Nimotop drug? Nimotop has the main ingredient nimodiphine and inactive ingredients such as: Ethanol 95%, Macrogol 400, Sodium citrate dihydrate, Anhydrous citric acid.
Nimotop drug is indicated in the treatment of the following diseases:
Prophylaxis and treatment of cases of vasospasm causing neurological ischemia after subarachnoid hemorrhage due to rupture of an intracranial aneurysm. Neurological disorders After sequelae with circulatory failure and primary degenerative process Contraindications to the use of Nimotop include:
Hypersensitivity to the components of the drug Patients with severe liver failure
2. Usage and dosage of Nimotop
2.1. How to use Nimotop drug is prepared in the form of film-coated tablets orally and intravenously. For oral form, it is necessary to take the drug with a little water, it should be taken 1 hour before eating or 2 hours after eating.
2.2. Dosage The dosage of Nimotop drug will depend on the disease condition and the patient's age such as:
Treatment of functional decline in the elderly with a dose of 1 tablet/time, 3 times a day Prevention and treatment Neurological defects due to ischemia after subarachnoid hemorrhage take 2 tablets, 6 times a day. If you forget to take a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue taking the medicine as scheduled. Do not arbitrarily use the drug twice the dose more than the treatment regimen. Using an overdose of Nimotop can cause serious symptoms such as nausea, vomiting, abdominal pain, weakness,...
3. Undesirable effects when using Nimotop
Some undesirable effects that may occur when using Nimotop include:
Decreased heart rate Lowering blood pressure Nausea Dizziness Headache Increased liver enzymes Extrasystolic sweating Diarrhea Stomach bloating Constipation Flu face Intestinal obstruction Thrombophlebitis Rash Elevated serum creatinine and blood nitrogen Before prescribing the drug, the physician always considers the benefits and effectiveness of Nimotop more than the risk of side effects. However, some cases when using Nimotop can still occur unwanted effects. In this case, the patient should immediately notify the medical staff for immediate intervention.
4. Some notes when using Nimotop
Some notes when using Nimotop include:
Inform your doctor about a history of allergy to Nimotop or any other allergies. Nimotop may contain ingredients that don't work and could cause an allergic reaction or other serious problems. Nimotop should be used with caution in cases of cerebral edema, increased intracranial pressure, renal failure, cardiovascular failure, low blood pressure, elderly patients with many underlying diseases. Nimodipine can cause premature loss of uterine contractions, but this effect does not affect delivery. Mothers with hypotension due to decreased peripheral blood vessels may be at risk of causing hypoxia of the fetal tissues. Therefore, during pregnancy, Nimotop should only be used when the risk and benefit has been assessed. According to one study, nimodipine or its metabolites were excreted in the milk of rats at much higher concentrations than in maternal plasma. However, there are no data on excretion in human milk. Therefore, it is best not to breastfeed during treatment with Nimotop.
5. Drug interactions
Some drugs that can interact with Nimotop include:
Magnesium salts, tacrolimus, amifostin, phenytoin, rituximab. Calcium channel blockers: Because the cardiovascular effects of these drugs are enhanced by the addition of nimodipine. Cimetidine: care should be taken when calculating the dose for the patient. Ranitidine and Famotidine: No significant effect on drug metabolism. Alpha1 blockers, azole antifungals, calcium channel blockers, cyclosporin, macrolide antibiotics, MAOIs, grapefruit juice: increase the effect of the drug. Rifampicin, carbamazepine, phenobarbital and valproic acid: decreased effect of nimodipine.
6. How to store Nimotop
Store Nimotop at a temperature of 15-30 degrees Celsius, protect from light and avoid humid places. Do not store Nimotop in a humid place or in the freezer. Different medicines will have different storage methods, so read the Nimotop storage instructions carefully on the packaging, or ask your pharmacist. Keep Nimotop out of the reach of children and family pets.
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